Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Tilman D, Rachner"'
Autor:
Nikolai P. Jaschke, Sophie Pählig, Anupam Sinha, Timon E. Adolph, Maria Ledesma Colunga, Maura Hofmann, Andrew Wang, Sylvia Thiele, Julian Schwärzler, Alexander Kleymann, Marc Gentzel, Herbert Tilg, Ben Wielockx, Lorenz C. Hofbauer, Martina Rauner, Andy Göbel, Tilman D. Rachner
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
A combination of cell line, transgenic mouse and human genetic data implicates a proinflammatory function of Dickkopf1 across malignant and non-malignant cells.
Externí odkaz:
https://doaj.org/article/08ca554bb4284badb614763c54f2ed47
Autor:
Daniel Martin Klotz, Jan Dominik Kuhlmann, Theresa Link, Maren Goeckenjan, Lorenz C. Hofbauer, Andy Göbel, Tilman D. Rachner, Pauline Wimberger
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundNeuropilin (NRP) is a transmembrane protein, which has been shown to be a pro-angiogenic mediator and implicated as a potential driver of cancer progression. NRP-1 up-regulation in ovarian cancer tissue predicts poor prognosis. However, the
Externí odkaz:
https://doaj.org/article/03ee71a135cd4b958849b2d257f515b6
Publikováno v:
Bone Research, Vol 9, Iss 1, Pp 1-10 (2021)
Abstract The regulation of whole-body homeostasis by the skeleton is mediated by its capacity to secrete endocrine signaling molecules. Although bone-derived hormones confer several adaptive benefits, their physiological functions also involve trade-
Externí odkaz:
https://doaj.org/article/23d2c4654cac4f21ad1a394be5314a7f
Autor:
Andy Göbel, Valentina M. Zinna, Stefania Dell’Endice, Nikolai Jaschke, Jan Dominik Kuhlmann, Pauline Wimberger, Tilman D. Rachner
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-17 (2020)
Abstract Background Ovarian cancer remains the most fatal gynecological malignancy. Current therapeutic options are limited due to late diagnosis in the majority of the cases, metastatic spread to the peritoneal cavity and the onset of chemo-resistan
Externí odkaz:
https://doaj.org/article/9646a631756b47db9076b98eec6dd654
Autor:
Juliane Lehmann, Sylvia Thiele, Ulrike Baschant, Tilman D. Rachner, Christof Niehrs, Lorenz C. Hofbauer, Martina Rauner
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102224- (2021)
Summary: The Wnt inhibitor Dickkopf-1 (DKK1) is a negative regulator of bone formation and bone mass and is dysregulated in various bone diseases. How DKK1 contributes to postmenopausal osteoporosis, however, remains poorly understood. Here, we show
Externí odkaz:
https://doaj.org/article/b49a9a7229e1475da4e88646176b9934
Autor:
Andrew J. Browne, Marie L. Kubasch, Andy Göbel, Peyman Hadji, David Chen, Martina Rauner, Friedrich Stölzel, Lorenz C. Hofbauer, Tilman D. Rachner
Publikováno v:
Breast Cancer Research, Vol 19, Iss 1, Pp 1-15 (2017)
Abstract Background The mammalian target of rapamycin inhibitor everolimus is approved as an antitumor agent in advanced estrogen receptor-positive breast cancer. Surrogate bone marker data from clinical trials suggest effects on bone metabolism, but
Externí odkaz:
https://doaj.org/article/444b18b9589b483c89b20d8fb31ffd36
Autor:
Andy Göbel, Jan D. Kuhlmann, Theresa Link, Pauline Wimberger, Cornelia Link-Rachner, Stefanie Thiele, Stefania Dell'Endice, Giulia Furesi, Dorit Breining, Martina Rauner, Lorenz C. Hofbauer, Tilman D. Rachner
Publikováno v:
Journal of Bone Oncology, Vol 16, Iss , Pp - (2019)
Background: Semaphorin 4D (Sema4D) is a glycoprotein that inhibits bone formation and has been associated with cancer progression and the occurrence of bone metastases. Recently, Sema4D expression has been linked to estrogen signaling in breast cance
Externí odkaz:
https://doaj.org/article/cd0e1a00e9d747cba09000e5c9236658
Autor:
Nikolai P. Jaschke, Tilman D. Rachner
Publikováno v:
Trends in Endocrinology & Metabolism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb254bdf4fc3ab816cd1806600d7eb60
https://doi.org/10.1016/j.tem.2023.04.001
https://doi.org/10.1016/j.tem.2023.04.001
Autor:
Charlotte Steenblock, Carlotta Hoffmann, Tilman D. Rachner, Florian Guggenbichler, Ermal Tahirukaj, Sacipi Bejtullah, Vsevolod A. Zinserling, Zsuzanna Varga, Stefan R. Bornstein, Nikolaos Perakakis
Publikováno v:
Diabetes aktuell. 20:43-50
ZUSAMMENFASSUNGÜber 10 % der deutschen Bevölkerung leiden an metabolischen Krankheiten wie Diabetes, Adipositas, oder nicht alkoholischer Steatohepatitis. Betroffene sind während der COVID-19-Pandemie einem besonderen Risiko ausgesetzt, gibt es do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be6d4ed30a72d923078ab4554de85e41
https://doi.org/10.1055/a-1754-9194
https://doi.org/10.1055/a-1754-9194
Autor:
Ann-Kathrin Bittner, Rainer Kimmig, Lorenz C. Hofbauer, Martina Rauner, Pauline Wimberger, Andrew Browne, Oliver Hoffmann, Kati Erdmann, Andy Göbel, Sabine Kasimir-Bauer, Tilman D. Rachner
Purpose:We assessed serum concentrations of the receptor activator of NFκB ligand (RANKL) and its decoy receptor, osteoprotegerin (OPG), two proteins implicated in the development and progression of breast cancer, in 509 patients with primary, nonme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472e23160ad5a32a18bbd11835bf45af
https://doi.org/10.1158/1078-0432.c.6526871.v1
https://doi.org/10.1158/1078-0432.c.6526871.v1
