Výsledky vyhledávání - "Tilly Fleckenstein"

Abstract 3588: Identification of a potent, orally bioavailable and selective MCT4 Inhibitor for the treatment of solid Warburg tumors

Autor: Aurélie Mallinger, Anette Funk, Nina Hambruch, Yansong Wang, Michael Albers, Olaf Kinzel, Christian Gege, Annika Bittman-Waetzig, Johannes Fabian, Barbara Herkert, Floriane Braun, Tilly Fleckenstein, Gero Fink, Claus Kremoser

Publikováno v: Cancer Research. 79:3588-3588

A key metabolic alteration in tumor cells is an elevated glycolysis rate, resulting in the production of increased amounts of protons and lactate leading to lactic acidosis within the tumor microenvironment. The tumor-promoting effects of lactic acid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::90641642e336b17a41fd2450b09e119f
https://doi.org/10.1158/1538-7445.am2019-3588

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Pichia pastoris-produced mucin-type fusion proteins with multivalent O-glycan substitution as targeting molecules for mannose-specific receptors of the immune system

Autor: Linda Lindberg, Magnus Sjöblom, Anki Gustafsson, Thomas Johansson, Ulrika Rova, Nathalie Chatzissavidou, Lena Strindelius, Jonas Ångström, Jan Holgersson, Tilly Fleckenstein

Publikováno v: Glycobiology. 21:1071-1086

Mannose-binding proteins like the macrophage mannose receptor (MR), the dendritic cell-specific intercellular adhesion molecule-3 grabbing non-integrin (DC-SIGN) and mannose-binding lectin (MBL) play crucial roles in both innate and adaptive immune r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a3487fe7ae8597fd376a53e1a3c1a3
https://doi.org/10.1093/glycob/cwr046

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