Determinants of heritable gene silencing for KRAB-dCas9 + DNMT3 and Ezh2-dCas9 + DNMT3 hit-and-run epigenome editing.

Autor: O'Geen H; Genome Center, University of California, Davis, CA 95616, USA., Tomkova M; Genome Center, University of California, Davis, CA 95616, USA., Combs JA; Genome Center, University of California, Davis, CA 95616, USA., Tilley EK; Genome Center, University of California, Davis, CA 95616, USA., Segal DJ; Genome Center, University of California, Davis, CA 95616, USA.; Department of Biochemistry and Molecular Medicine, University of California, Davis, CA 95616, USA.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2022 Apr 08; Vol. 50 (6), pp. 3239-3253.