Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Till F, Schäberle"'
Autor:
Katherine L. Fenn, Jim E. Horne, Joel A. Crossley, Nils Böhringer, Romany J. Horne, Till F. Schäberle, Antonio N. Calabrese, Sheena E. Radford, Neil A. Ranson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The outer membrane is a formidable barrier that protects Gram-negative bacteria against environmental threats. Its integrity requires the correct folding and insertion of outer membrane proteins (OMPs) by the membrane-embedded β-barrel asse
Externí odkaz:
https://doaj.org/article/e2d6b62a22094d6bb6804c36a81d4e8a
Autor:
Felix Getzke, Lei Wang, Guillaume Chesneau, Nils Böhringer, Fantin Mesny, Nienke Denissen, Hidde Wesseler, Priscilla Tijesuni Adisa, Michael Marner, Paul Schulze-Lefert, Till F. Schäberle, Stéphane Hacquard
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Various microbes isolated from healthy plants are detrimental under laboratory conditions, indicating the existence of molecular mechanisms preventing disease in nature. Here, we demonstrated that application of sodium chloride (NaCl) in nat
Externí odkaz:
https://doaj.org/article/edbb13a8a72c4e9aa3c88154de8aa4e6
Autor:
Pelin Erkoc, Susanne Schiffmann, Thomas Ulshöfer, Marina Henke, Michael Marner, Jonas Krämer, Reinhard Predel, Till F. Schäberle, Sabine Hurka, Ludwig Dersch, Andreas Vilcinskas, Robert Fürst, Tim Lüddecke
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110209- (2024)
Summary: Arthropod venoms contain bioactive molecules attractive for biomedical applications. However, few of these have been isolated, and only a tiny number has been characterized. Pseudoscorpions are small arachnids whose venom has been largely ov
Externí odkaz:
https://doaj.org/article/c364243d69cf4cc2a8185b42cf657cc3
Functional in vitro and in vivo analysis of biosynthetic genes by heterologous expression in E. coli
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102531- (2023)
Summary: Biosynthetic gene clusters of natural products often harbor genes of unknown function, which are difficult to characterize. Here, we present a protocol for the functional analysis in vitro and in vivo of these biosynthetic genes by heterolog
Externí odkaz:
https://doaj.org/article/51124c51be8c44bdb94e5941c61d5a2f
Autor:
Markus Oberpaul, Stephan Brinkmann, Michael Marner, Sanja Mihajlovic, Benedikt Leis, Maria A. Patras, Christoph Hartwig, Andreas Vilcinskas, Peter E. Hammann, Till F. Schäberle, Marius Spohn, Jens Glaeser
Publikováno v:
Microbial Biotechnology, Vol 15, Iss 2, Pp 415-430 (2022)
Summary High‐throughput platforms facilitating screening campaigns of environmental samples are needed to discover new products of natural origin counteracting the spreading of antimicrobial resistances constantly threatening human and agricultural
Externí odkaz:
https://doaj.org/article/92d50823088e47c7a9ae8b55a5988d82
Autor:
Michael Marner, Laura Kolberg, Julia Horst, Nils Böhringer, Johannes Hübner, I Dewa M. Kresna, Yang Liu, Ute Mettal, Lei Wang, Melanie Meyer-Bühn, Sanja Mihajlovic, Matthias Kappler, Till F. Schäberle, Ulrich von Both
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT The emergence and spread of antimicrobial resistance (AMR) in Gram-negative pathogens, such as carbapenem-resistant Pseudomonas aeruginosa, pose an increasing threat to health care. Patients with immunodeficiencies or chronic pulmonary disea
Externí odkaz:
https://doaj.org/article/33dc2de94e8a4e6fb2ddc2de32f8329d
Autor:
Katerina Vocadlova, Tim Lüddecke, Maria A. Patras, Michael Marner, Christoph Hartwig, Karel Benes, Vladimir Matha, Petr Mraz, Till F. Schäberle, Andreas Vilcinskas
Publikováno v:
Microorganisms, Vol 11, Iss 8, p 2067 (2023)
Honey bees coexist with fungi that colonize hive surfaces and pollen. Some of these fungi are opportunistic pathogens, but many are beneficial species that produce antimicrobial compounds for pollen conservation and the regulation of pathogen populat
Externí odkaz:
https://doaj.org/article/fd9db4e4adff434cb7f51d64026b1144
Autor:
Stephan Brinkmann, Michael Kurz, Maria A. Patras, Christoph Hartwig, Michael Marner, Benedikt Leis, André Billion, Yolanda Kleiner, Armin Bauer, Luigi Toti, Christoph Pöverlein, Peter E. Hammann, Andreas Vilcinskas, Jens Glaeser, Marius Spohn, Till F. Schäberle
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT With progress in genome sequencing and data sharing, 1,000s of bacterial genomes are publicly available. Genome mining—using bioinformatics tools in terms of biosynthetic gene cluster (BGC) identification, analysis, and rating—has become
Externí odkaz:
https://doaj.org/article/b00be26548a845d2bde59a806ef3a821
Autor:
Cora Hertzer, Stefan Kehraus, Nils Böhringer, Fontje Kaligis, Robert Bara, Dirk Erpenbeck, Gert Wörheide, Till F. Schäberle, Heike Wägele, Gabriele M. König
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 1596-1605 (2020)
Investigations on the biochemical relationship between Doriprismatica stellata (Chromodorididae, Doridoidea) nudibranchs, their egg ribbons, and the associated dietary sponge Spongia cf. agaricina (Demospongiae, Porifera) led to the isolation of the
Externí odkaz:
https://doaj.org/article/cd68ba7be878403191815957dc90020c
Autor:
Cora Hertzer, Nani Ingrid Jacquline Undap, Adelfia Papu, Dhaka Ram Bhandari, Stefan Aatz, Stefan Kehraus, Fontje Kaligis, Robert Bara, Till F. Schäberle, Heike Wägele, Gabriele M. König
Publikováno v:
Diversity, Vol 15, Iss 2, p 304 (2023)
Five Chromodoris species from North Sulawesi, Indonesia, were investigated for their sequestration of marine natural products. The cytotoxic 2-thiazolidinone macrolide latrunculin A (LatA) was the major metabolite in all examined Chromodoris species,
Externí odkaz:
https://doaj.org/article/311e9b5cea7c4d7c8d661618df594ec4