Zobrazeno 1 - 10 of 40 pro vyhledávání: '"Tijen Önkol"'
1
Akademický článek
3-({4-[(2-Methylbenzylidene)amino]-5-sulfanylidene-1H-1,2,4-triazol-3-yl}methyl)-1,3-benzoxazol-2(3H)-one
Autor: Abdullah Aydın, Nuray Hekimoğlu, Mehmet Akkurt, Tijen Önkol, Şölen Urlu Çiçekli, Orhan Büyükgüngör
Publikováno v: Acta Crystallographica Section E, Vol 69, Iss 2, Pp o169-o170 (2013)
In the title compound, C18H15N5O2S, a weak intramolecular C—H...S hydrogen bond results in a small dihedral angle of 3.71 (9)° between the methylphenyl and triazole rings, which, in turn, form dihedral angles of 80.09 (8) and 77.32 (8)°, respecti
Externí odkaz: https://doaj.org/article/2b34eeb7c32b457897054ebe84228706
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2
Akademický článek
2-(6-Benzoyl-2-oxo-1,3-benzothiazol-3-yl)acetic acid
Autor: Abdullah Aydın, Mehmet Akkurt, Tijen Önkol, Orhan Büyükgüngör, M. Fethi Şahin
Publikováno v: Acta Crystallographica Section E, Vol 66, Iss 1, Pp o168-o168 (2010)
In the title compound, C16H11NO4S, the nine-membered fused ring is nearly planar, with maximum deviations from the mean plane of −0.022 (1) Å for the N atom and 0.011 (1) Å for the S atom, and makes a dihedral angle of 53.56 (7)° with the phenyl
Externí odkaz: https://doaj.org/article/92679bca8911464f8312a10c9f5b85f6
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5
Design, Synthesis, and Biological Evaluation of Some Benzothiazolone Derivatives as Cholinesterase Inhibitors
Autor: Mehmet Abdullah Alagöz, Didem Akkaya, Gülnur Arslan, Berk Uludağ, Zeynep Özdemir, Burak Barut, Tijen Önkol, Suat Sari
Publikováno v: ChemistrySelect. 7
© 2022 Wiley-VCH GmbH.In this study, nine new benzothiazolone derivatives (6 a–i) were designed and synthesized to identify potent cholinesterase inhibitors. The compounds were tested in vitro against acetylcholinesterase (AChE) and butyrylcholine
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff04c003407d42537ed7a6d970c542c1
https://doi.org/10.1002/slct.202203250
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6
Inhibition of Cholinesterases by Benzothiazolone Derivatives
Autor: Mehmet Abdullah Alagöz, Seong-Min Kim, Jong Min Oh, Gülnur Arslan, Zeynep Özdemir, Suat Sari, Azime Berna Özçelik, Tijen Önkol, Daniela Trisciuzzi, Orazio Nicolotti, Hoon Kim, Bijo Mathew
Publikováno v: Processes; Volume 10; Issue 9; Pages: 1872
Thirteen benzothiazolone derivatives (M1–M13) were synthesized and evaluated for their inhibitory activity against cholinesterases (ChEs) and monoamine oxidases (MAOs). All the compounds inhibited ChEs more effectively than MAOs. In addition, most
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5359a2e05e97c3fda4bed6dd272136c
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7
Peroxisome Proliferator-Activated Receptors as Superior Targets for Treating Diabetic Disease, Design Strategies - Review Article
Autor: Mohammed T Qaoud, Ihab Al-masri, Tijen Önkol
Publikováno v: Turk J Pharm Sci
Thiazolidinedione (TZD), a class of drugs that are mainly used to control type 2 diabetes mellitus (T2DM), acts fundamentally as a ligand of peroxisome proliferator-activated receptors (PPARs). Besides activating pathways responsible for glycemic con
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20fe555c804e3b27278cd7320c11bb9d
https://europepmc.org/articles/PMC9254082/
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8
Synthesis of New 1-Aryl-2-(3,5-dimethylpyrazol-1-yl)ethanone Oxime Ether Derivatives and Investigation of Their Cytotoxic Effects
Autor: Bijo Mathew, Hoon Kim, Mehmet Abdullah Alagöz, Mohamed A. Abdelgawad, Mohammed M. Ghoneim, Ahmed Khames, Tijen Önkol, Ceylan Hepokur, Arzu Karakurt, Emine Şalva
Publikováno v: Processes, Vol 9, Iss 2019, p 2019 (2021)
Processes
Volume 9
Issue 11
In this study, 12 new 1-aryl-2-(3,5-dimethylpyrazol-1-yl)ethanone oxime ether derivatives were designed and synthesized to investigate their cytotoxic effects. The in vitro cytotoxic activities of the compounds were evaluated against cervix, colon, b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46642c4bd6b0c14be57bb095972dc11
https://hdl.handle.net/20.500.12418/13219
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10
Microwave-assisted synthesis and pharmacological screening of some triazolothiadiazole derivatives
Autor: Kevser Erol, Yeşim Özkan, Tijen Önkol, Bilge Çakir, Engin Yildirim, Ozge Gorgu
Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Vol 56 (2020)
Brazilian Journal of Pharmaceutical Sciences, Volume: 56, Article number: e18111, Published: 16 MAR 2020
Brazilian Journal of Pharmaceutical Sciences; Vol. 56 (2020); e18111
Brazilian Journal of Pharmaceutical Sciences; v. 56 (2020); e18111
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
In this study, twenty-two new [1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles (5a-n, 6a-h) were synthesized under microwave irradiation (MWI). The chemical structures of the compounds were elucidated by their IR, 1 H-NMR, LC-MS, and elemental analysis. The
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6cd1815c1ee68a851e07779b11b6232
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100526&tlng=en
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