Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Tijda Argun"'
Autor:
Sanchari Bhattacharyya, Shimon Bershtein, Jin Yan, Tijda Argun, Amy I Gilson, Sunia A Trauger, Eugene I Shakhnovich
Publikováno v:
eLife, Vol 5 (2016)
Gene dosage toxicity (GDT) is an important factor that determines optimal levels of protein abundances, yet its molecular underpinnings remain unknown. Here, we demonstrate that overexpression of DHFR in E. coli causes a toxic metabolic imbalance tri
Externí odkaz:
https://doaj.org/article/3c5237d307ba4c0cb4d775dbc0e60882
Autor:
Sunia A. Trauger, Eugene I. Shakhnovich, Amy I. Gilson, Jin Yan, Sanchari Bhattacharyya, Tijda Argun, Shimon Bershtein
Publikováno v:
eLife, Vol 5 (2016)
eLife
eLife
Several genes exhibit gene dosage toxicity yet its molecular underpinnings remain unknown. Here we demonstrate that overexpression of DHFR inE. colicauses toxic metabolic imbalance triggered by interactions with several enzymes involved in 1-carbon m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e9efabb7b3d61525f5f7bb669ee90f
https://doi.org/10.1101/066373
https://doi.org/10.1101/066373
