Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tiina Raatikainen"'
Autor:
Heidi M. Haikala, Johanna M. Anttila, Elsa Marques, Tiina Raatikainen, Mette Ilander, Henna Hakanen, Hanna Ala-Hongisto, Mariel Savelius, Diego Balboa, Bjoern Von Eyss, Vilja Eskelinen, Pauliina Munne, Anni I. Nieminen, Timo Otonkoski, Julia Schüler, Teemu D. Laajala, Tero Aittokallio, Harri Sihto, Johanna Mattson, Päivi Heikkilä, Marjut Leidenius, Heikki Joensuu, Satu Mustjoki, Panu Kovanen, Martin Eilers, Joel D. Leverson, Juha Klefström
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Elevated MYC levels can sensitize tumor cells to apoptosis. In this study, the authors demonstrate that AMPK activation and BCL-2/BCL-XL inhibition have a synergistic effect on apoptosis, and that together with anti PD-1 therapy they can suppress Myc
Externí odkaz:
https://doaj.org/article/d3f1f919795e44fe8702e5ba84a712b6
Autor:
Heidi M. Haikala, Johanna M. Anttila, Elsa Marques, Tiina Raatikainen, Mette Ilander, Henna Hakanen, Hanna Ala-Hongisto, Mariel Savelius, Diego Balboa, Bjoern Von Eyss, Vilja Eskelinen, Pauliina Munne, Anni I. Nieminen, Timo Otonkoski, Julia Schüler, Teemu D. Laajala, Tero Aittokallio, Harri Sihto, Johanna Mattson, Päivi Heikkilä, Marjut Leidenius, Heikki Joensuu, Satu Mustjoki, Panu Kovanen, Martin Eilers, Joel D. Leverson, Juha Klefström
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article contained an error in Fig. 7. In panel b, the survival curves were shifted relative to the y axis. This error has been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/be938228d9c14a09b1d43012150cc2cd
Autor:
Kati Belitškina, Hanna-Ala Hongisto, Jeroen Pouwels, Olga Klezovitch, Outi Monni, Shishir M. Pant, Pirjo Laakkonen, Topi A. Tervonen, Ilida Suleymanova, Valeri Vasioukhin, Johanna Englund, Tiina Raatikainen, Satu Kuure, Shuo Li, Juha Klefström, Denis Belitskin, Qingyu Wu, Pauliina Munne
Publikováno v:
EMBO Reports
Transforming growth factor‐beta (TGFβ) is a multifunctional cytokine with a well‐established role in mammary gland development and both oncogenic and tumor‐suppressive functions. The extracellular matrix (ECM) indirectly regulates TGFβ activi
Autor:
Martin Eilers, Johanna Mattson, Elsa Marques, Johanna M. Anttila, Joel D. Leverson, Panu E. Kovanen, Juha Klefström, Mariel Savelius, Tiina Raatikainen, Heidi M. Haikala, Satu Mustjoki, Mette Ilander, Marjut Leidenius, Päivi Heikkilä, Henna Hakanen, Heikki Joensuu
Publikováno v:
Cancer Research. 79:LB-189
Elevated MYC levels sensitize tumor cells to apoptosis but the therapeutic potential of this mechanism remains unclear. We find, in a model of MYC-driven breast cancer, that pharmacological activation of AMPK dramatically synergizes with BCL-2/BCL-XL
Autor:
Johanna Mattson, Martin Eilers, Harri Sihto, Henna Hakanen, Heikki Joensuu, Päivi Heikkilä, Mette Ilander, Joel D. Leverson, Timo Otonkoski, Teemu D. Laajala, Panu E. Kovanen, Johanna M. Anttila, Bjoern von Eyss, Vilja Eskelinen, Tiina Raatikainen, Elsa Marques, Julia Schüler, Diego Balboa, Tero Aittokallio, Mariel Savelius, Pauliina Munne, Hanna Ala-Hongisto, Juha Klefström, Marjut Leidenius, Heidi M. Haikala, Anni I. Nieminen, Satu Mustjoki
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
Nature Communications
Nature Communications
The original version of this Article contained an error in Fig. 7. In panel b, the survival curves were shifted relative to the y axis. This error has been corrected in both the PDF and HTML versions of the Article.