Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Tiina Keisala"'
Autor:
Sami Purmonen, Helle-Evi Simovart, Marianne Kuuslahti, Tiina Keisala, Antti Kaipia, Teuvo L.J. Tammela, Pasi Pöllanen, Helen Orro, Kersti Kokk
Publikováno v:
Journal of Andrology. 32:49-54
The role of luteinizing hormone (LH) in the regulation of normal reproductive functions in males and females is quite well established. Besides the expression of LH receptors in the target cells in gonads, it has been found in several extragonadal or
Autor:
M. Käenmäki, Heikki Rauvala, Oleg Kambur, Natalia Kulesskaya, J. Arturo García-Horsman, Pekka T. Männistö, Anne Tammimäki, Eeva Karvonen, Tiina Keisala
Publikováno v:
Psychopharmacology. 211:389-401
Catechol-O-methyltransferase (COMT) has soluble (S-COMT) and membrane bound (MB-COMT) isoforms. Our aims were to assess the behavioral phenotype of S-COMT mutant mice and to clarify the role of MB-COMT in dopamine metabolism in different brain areas.
Autor:
Allan V. Kalueff, Tiina Keisala, Pentti Tuohimaa, Jing Zou, Anna Minasyan, Ilmari Pyykkö, Yan-Ru Lou
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 115:91-97
Hypervitaminosis vitamin D(3) has been recently implicated in premature aging through the regulation of 1alpha hydroxylase expression by klotho and fibroblast growth factor-23 (Fgf-23). Here we examined whether the lack of hormonal function of vitami
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 104:274-280
Vitamin D is a seco-steroid hormone with multiple actions in the brain, mediated through the nuclear vitamin D receptor (VDR). We have recently shown that mutant mice lacking functional VDR demonstrate altered emotional behavior and specific motor de
Publikováno v:
Psychoneuroendocrinology. 34
This is a mini-review of vitamin D(3), its active metabolites and their functioning in the central nervous system (CNS), especially in relation to nervous system pathologies and aging. The vitamin D(3) endocrine system consists of 3 active calciphero
Autor:
Ilmari Pyykkö, Allan V. Kalueff, Esko Toppila, Jing Zou, Heimo Syvälä, Anna Minasyan, Yan-Ru Lou, Tiina Keisala, Pentti Tuohimaa, Ya Zhang
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 114(3-5)
The vitamin D endocrine system is essential for calcium and bone homeostasis. Vitamin D deficits are associated with muscle weakness and osteoporosis, whereas vitamin D supplementation may improve muscle function, body sway and frequency of falls, gr
Autor:
Allan V. Kalueff, Tiina Keisala, Anna Minasyan, Jing-Huan Wang, Pentti Tuohimaa, Tiina Solakivi
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 113(3-5)
Vitamin D insufficiency has been reported to be associated with increased blood cholesterol concentrations. Here we used two strains of VDR knock-out (VDR-KO) mice to study whether a lack of vitamin D action has any effect on cholesterol metabolism.
Autor:
Anna Minasyan, Pentti Tuohimaa, Senthil R Kumar, Justin L. LaPorte, Dennis L. Murphy, Tiina Keisala, Allan V. Kalueff
Publikováno v:
Nature protocols. 3(1)
Animal behavioral models are crucial for neurobiological research, allowing for the thorough investigation of brain pathogenesis to be performed. In both animals and humans, anxiety has long been linked to vestibular disorders. However, although ther
Autor:
Anna Minasyan, Jing-Huan Wang, Ya Zhang, Jing Zou, Pentti Tuohimaa, Tiina Keisala, Yan-Ru Lou, Ilmari Pyykkö, Alan Kalueff
Publikováno v:
Audiologyneuro-otology. 13(4)
Background: Both hypo- and hypervitaminosis D can cause sensorineural hearing loss, and aural symptoms due to vitamin D insufficiency are especially common during gravidity. Hormonal forms of vitamin D regulate transcription by binding with the high-
Autor:
Anna Minasyan, Jing-Huan Wang, Ulla Järvelin, Allan V. Kalueff, Tuula Hämäläinen, Tiina Keisala, Pentti Tuohimaa
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 104(3-5)
1Alpha,25(OH)2D3, the hormonal form of vitamin D, is a neuroactive seco-steroid hormone with multiple functions in the brain. Most of these effects are mediated through the nuclear vitamin D receptor (VDR), widely distributed in the central nervous s