Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Tiina Heliö"'
Publikováno v:
BMC Cardiovascular Disorders, Vol 23, Iss 1, Pp 1-5 (2023)
Abstract Background Primary tumors of the heart are a rare phenomenon. Lymphatic malformations are congenital anomalies of the lymphatic system that tend to grow progressively. Lymphatic malformations are typically found in the cervical and axillary
Externí odkaz:
https://doaj.org/article/c2fbee5bfb42480abbc6ade4f760b9f7
Autor:
Krista Heliö, Marcos Cicerchia, Julie Hathaway, Johanna Tommiska, Johanna Huusko, Inka Saarinen, Lotta Koskinen, Mikko Muona, Ville Kytölä, Janica Djupsjöbacka, Massimiliano Gentile, Pertteli Salmenperä, Tero-Pekka Alastalo, Christian Steinberg, Tiina Heliö, Jussi Paananen, Samuel Myllykangas, Juha Koskenvuo
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundFamilial dilated cardiomyopathy (DCM) causes heart failure and may lead to heart transplantation. DCM is typically a monogenic disorder with autosomal dominant inheritance. Currently disease-causing variants have been reported in over 60 ge
Externí odkaz:
https://doaj.org/article/ff822a1fa0e341c99b73042e74defdfd
Autor:
Caroline Le Dour, Maria Chatzifrangkeskou, Coline Macquart, Maria M. Magiera, Cécile Peccate, Charlène Jouve, Laura Virtanen, Tiina Heliö, Katriina Aalto-Setälä, Silvia Crasto, Bruno Cadot, Déborah Cardoso, Nathalie Mougenot, Daniel Adesse, Elisa Di Pasquale, Jean-Sébastien Hulot, Pekka Taimen, Carsten Janke, Antoine Muchir
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Lamin A/C gene mutations cause dilated cardiomyopathy associated with cofilin-1 phosphorylation and actin destabilization. Here, the authors show that phosphorylated cofilin-1 blunts the MRTF-A/SRF axis, leading to decreased tubulin acetylation and a
Externí odkaz:
https://doaj.org/article/ef932080f9164edd9c93891a4153a646
Autor:
Øystein Karlstad, Lars Køber, Tommi Härkänen, Anders Husby, Jørgen Vinsløv Hansen, Anders Hviid, Rickard Ljung, Jesper Dahl, Hanne Løvdal Gulseth, Tiina Heliö, Nina Gunnes, Petteri Hovi, Nicklas Pihlström
Publikováno v:
BMJ Medicine, Vol 2, Iss 1 (2023)
Objective To investigate the clinical outcomes of myocarditis associated with mRNA vaccines against the SARS-CoV-2 virus compared with other types of myocarditis.Design Population based cohort study.Setting Nationwide register data from four Nordic c
Externí odkaz:
https://doaj.org/article/61916c663ccb4983bfcc43f2423256de
Autor:
Krista Heliö, Eveliina Brandt, Satu Vaara, Sini Weckström, Liisa Harjama, Riina Kandolin, Johanna Järviö, Katariina Hannula-Jouppi, Tiina Heliö, Miia Holmström, Juha W. Koskenvuo
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundPathogenic variants in DSP associate with cardiac and cutaneous manifestations including arrhythmogenic right ventricular cardiomyopathy, dilated cardiomyopathy, curly or wavy hair, and palmoplantar keratoderma (PPK). Episodes of myocardial
Externí odkaz:
https://doaj.org/article/acb68496b6f44932b464562c1ecf086a
Autor:
Teemu Vepsäläinen, Tiina Heliö, Catalina Vasilescu, Laura Martelius, Sini Weckström, Juha Koskenvuo, Anita Hiippala, Tiina Ojala
Publikováno v:
Cardiogenetics, Vol 12, Iss 1, Pp 122-132 (2022)
Cardiomyopathies (CMPs) are a heterogeneous group of diseases, frequently genetic, affecting the heart muscle. The symptoms range from asymptomatic to dyspnea, arrhythmias, syncope, and sudden cardiac death. This study is focused on MYH7 (beta-myosin
Externí odkaz:
https://doaj.org/article/ed1a1519b31247ce813bde2d4c974c45
Autor:
Aria Yar, Valtteri Uusitalo, Satu M Vaara, Miia Holmström, Aino-Maija Vuorinen, Tiina Heliö, Riitta Paakkanen, Sari Kivistö, Suvi Syväranta, Johanna Hästbacka
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0282394 (2023)
BackgroundLong-term symptoms are frequent after coronavirus disease 2019 (COVID-19). We studied the prevalence of post-acute myocardial scar on cardiac magnetic resonance imaging (CMR) in patients hospitalized due to COVID-19 and its association with
Externí odkaz:
https://doaj.org/article/620fe932f760472fa9b196527ec4234d
Autor:
Gun West, Minttu Turunen, Anna Aalto, Laura Virtanen, Song-Ping Li, Tiina Heliö, Annika Meinander, Pekka Taimen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Lamins A and C are nuclear intermediate filament proteins that form a proteinaceous meshwork called lamina beneath the inner nuclear membrane. Mutations in the LMNA gene encoding lamins A and C cause a heterogenous group of inherited degenerative dis
Externí odkaz:
https://doaj.org/article/36547d1f42a541a680ba43e8f60e69a4
Autor:
Julie Hathaway, Krista Heliö, Inka Saarinen, Jonna Tallila, Eija H. Seppälä, Sari Tuupanen, Hannu Turpeinen, Tiia Kangas-Kontio, Jennifer Schleit, Johanna Tommiska, Ville Kytölä, Miko Valori, Mikko Muona, Johanna Sistonen, Massimiliano Gentile, Pertteli Salmenperä, Samuel Myllykangas, Jussi Paananen, Tero-Pekka Alastalo, Tiina Heliö, Juha Koskenvuo
Publikováno v:
BMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Genetic testing in hypertrophic cardiomyopathy (HCM) is a published guideline-based recommendation. The diagnostic yield of genetic testing and corresponding HCM-associated genes have been largely documented by single center studi
Externí odkaz:
https://doaj.org/article/1a8328a56c1a4010ae5eb9b873a650f5
Autor:
Joona Valtonen, Chandra Prajapati, Reeja Maria Cherian, Sari Vanninen, Marisa Ojala, Krista Leivo, Tiina Heliö, Juha Koskenvuo, Katriina Aalto-Setälä
Publikováno v:
Biomedicines, Vol 11, Iss 6, p 1558 (2023)
Hypertrophic cardiomyopathy (HCM) is one of the most common genetic cardiac diseases; it is primarily caused by mutations in sarcomeric genes. However, HCM is also associated with mutations in non-sarcomeric proteins and a Finnish founder mutation fo
Externí odkaz:
https://doaj.org/article/345ec3896cab48608d201fb61509446e