Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Tiina, Nieminen"'
Autor:
Niko Järveläinen, Paavo J. Halonen, Jussi Nurro, Antti Kuivanen, Juho Pajula, Miikka Tarkia, Maria Grönman, Antti Saraste, Johanna Laakkonen, Pyry Toivanen, Tiina Nieminen, Tuomas T. Rissanen, Juhani Knuuti, Seppo Ylä-Herttuala
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract This preliminary study investigated if VEGFR-2 selective adenoviral Vammin (AdVammin) gene therapy could induce angiogenesis and increase perfusion in the healthy porcine myocardium. Also, we determined using a clinically relevant large anim
Externí odkaz:
https://doaj.org/article/1dbb7bbfe5c546bdb83e1bdc390a088d
Autor:
Sharada Mokkapati, Vikram M. Narayan, Ganiraju C. Manyam, Amy H. Lim, Jonathan J. Duplisea, Andrea Kokorovic, Tanner S. Miest, Anirban P. Mitra, Devin Plote, Selvalakshmi Selvaraj Anand, Michael J. Metcalfe, Kenneth Dunner, Jr., Burles A. Johnson, Bogdan A. Czerniak, Tiina Nieminen, Tommi Heikura, Seppo Yla-Herttuala, Nigel R. Parker, Kimberley S. Schluns, David J. McConkey, Colin P. Dinney
Publikováno v:
Molecular Therapy: Oncolytics, Vol 26, Iss , Pp 141-157 (2022)
Interferon alpha (IFNα) gene therapy is emerging as a new treatment option for patients with non-muscle invasive bladder cancer (NMIBC). Adenoviral vectors expressing IFNα have shown clinical efficacy treating bacillus Calmette-Guerin (BCG)-unrespo
Externí odkaz:
https://doaj.org/article/5de742af926648bcab7840c44c6fac3e
Autor:
Reetta A. E. Eriksson, Tiina Nieminen, Lionel Galibert, Sanna K. Peltola, Petra Tikkanen, Piia Käyhty, Hanna M. Leinonen, Igor Oruetxebarria, Saana Lepola, Anniina J. Valkama, Eevi M. Lipponen, Hanna P. Lesch, Seppo Ylä-Herttuala, Kari J. Airenne
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/577226a018c4442398fc2f758afd0a1c
Autor:
Lionel Galibert, Amira Hyvönen, Reetta A. E. Eriksson, Salla Mattola, Vesa Aho, Sami Salminen, Justin D. Albers, Sanna K. Peltola, Saija Weman, Tiina Nieminen, Seppo Ylä-Herttuala, Hanna P. Lesch, Maija Vihinen-Ranta, Kari J. Airenne
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract With a limited coding capacity of 4.7 kb, adeno-associated virus (AAV) genome has evolved over-lapping genes to maximise the usage of its genome. An example is the recently found ORF in the cap gene, encoding membrane-associated accessory pr
Externí odkaz:
https://doaj.org/article/cfb778447b9c4cc69e2061b9fd481166
Autor:
Reetta A. E. Eriksson, Tiina Nieminen, Lionel Galibert, Sanna K. Peltola, Petra Tikkanen, Piia Käyhty, Hanna M. Leinonen, Igor Oruetxebarria, Saana Lepola, Anniina J. Valkama, Eevi M. Lipponen, Hanna P. Lesch, Seppo Ylä-Herttuala, Kari J. Airenne
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Gene therapy would greatly benefit from a method to regulate therapeutic gene expression temporally. Riboswitches are small RNA elements that have been studied for their potential use in turning transgene expression on or off by ligand binding. We co
Externí odkaz:
https://doaj.org/article/bac6cbe4bcff4b7981f043f3a2f22c28
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Graphical Abstract
Externí odkaz:
https://doaj.org/article/f86914d9ec104ff798544c8450dc46ba
Autor:
Henna Korpela, Olli-Pekka Hätinen, Tiina Nieminen, Rahul Mallick, Pyry Toivanen, Jonna Airaksinen, Kaisa Valli, Mikko Hakulinen, Pekka Poutiainen, Jussi Nurro, Seppo Ylä-Herttuala
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103533- (2021)
Summary: Vascular endothelial growth factor B (VEGF-B) is an interesting therapeutic candidate for coronary artery disease. However, it can also cause ventricular arrhythmias, potentially preventing its use in clinics. We cloned VEGF-B isoforms with
Externí odkaz:
https://doaj.org/article/b15e0250c9894d889ee8b3933a4498ad
Autor:
Juha Tiainen, Terho Hyvönen, Marleena Hagner, Erja Huusela-Veistola, Pauliina Louhi, Antti Miettinen, Tiina Nieminen, Ansa Palojärvi, Tuomas Seimola, Pauliina Taimisto, Perttu Virkajärvi
Publikováno v:
Agricultural and Food Science, Vol 29, Iss 2 (2020)
Biodiversity degradation is a national and global problem which is interconnected with land use and climate change. All these are major unsolved questions and their interactions are only partly understood. Agriculture and especially cattle farming is
Externí odkaz:
https://doaj.org/article/70ace77e5e4c4691ad305731f9cba58a
Autor:
Pyry I. Toivanen, Tiina Nieminen, Johanna P. Laakkonen, Tommi Heikura, Minna U. Kaikkonen, Seppo Ylä-Herttuala
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Vascular Endothelial Growth Factors (VEGFs) are promising molecules for the treatment of ischemic diseases by pro-angiogenic therapy. Snake venom VEGFs are a novel subgroup with unique receptor binding profiles and as such are potential new
Externí odkaz:
https://doaj.org/article/027dea479a8e4616b514504c345ea716
Autor:
Suvi Jauhiainen, Johanna P. Laakkonen, Kirsi Ketola, Pyry I. Toivanen, Tiina Nieminen, Takeshi Ninchoji, Anna-Liisa Levonen, Minna U. Kaikkonen, Seppo Ylä-Herttuala
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Vascular endothelial growth factors (VEGFs) are key mediators of endothelial cell (EC) function in angiogenesis. Emerging knowledge also supports the involvement of axon guidance-related factors in the regulation of angiogenesis and vascular patterni
Externí odkaz:
https://doaj.org/article/f2c61d3554834120acd95abb744ff1d3