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nor-1 Regulates Hippocampal Axon Guidance, Pyramidal Cell Survival, and Seizure Susceptibility

Publikováno v: Molecular and Cellular Biology. 24:9070-9078

nor-1 (NR4A3) is a member of the nuclear receptor family of transcription factors, whose developmental and physiological functions are poorly understood. nor-1 (NR4A3) and two highly homologous transcription factors, nurr1 (NR4A2) and nur77 (NR4A1),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e876857e75578521d6c9ece7fe65e22e
https://doi.org/10.1128/mcb.24.20.9070-9078.2004

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The Nuclear Receptor Nor-1 Is Essential for Proliferation of the Semicircular Canals of the Mouse Inner Ear

Autor: Quiana Burton, Tiia Ponnio, Orla M. Conneely, Doris K. Wu, Fred A. Pereira

Publikováno v: Molecular and Cellular Biology. 22:935-945

Nor-1 belongs to the nur subfamily of nuclear receptor transcription factors. The precise role of Nor-1 in mammalian development has not been established. However, recent studies indicate a function for this transcription factor in oncogenesis and ap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a88f8cbf99f44dd7120b59f09f0c31
https://doi.org/10.1128/mcb.22.3.935-945.2002

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Involvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neurons

Autor: Tiia Ponnio, J. Peter H. Burbach, Orla M. Conneely, Marten P. Smidt, Simone M. Smits

Publikováno v: The European journal of neuroscience. 18(7)

The mesencephalic dopaminergic (mesDA) system is involved in many brain functions including motor control and motivated behaviour, and is of clinical importance because of its implication in psychiatric disorders and Parkinson's disease. Nurr1, a mem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::675816e23d2a9a5e6603f32e16041950
https://pubmed.ncbi.nlm.nih.gov/14622207

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Activation of nuclear orphan receptor NURR1 transcription by NF-kappa B and cyclic adenosine 5'-monophosphate response element-binding protein in rheumatoid arthritis synovial tissue

Autor: Alice N. McEvoy, Orla M. Conneely, Tiia Ponnio, Barry Bresnihan, Oliver FitzGerald, Evelyn P. Murphy, E. Murphy

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 168(6)

Modulation of the NURR subfamily of nuclear receptors may be an important mechanism regulating pathways associated with inflammatory joint disease. We examined the signaling mechanisms through which inflammatory mediators, produced by rheumatoid arth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42248c76a1ac208c7e122809b66a5116
https://pubmed.ncbi.nlm.nih.gov/11884470

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