Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Tiia, Snäkä"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Preclinical mouse models are critical for understanding the pathophysiological response to infections and developing treatment strategies for sepsis. In keeping with ethical values, researchers follow guidelines to minimize the suffering of
Externí odkaz:
https://doaj.org/article/29691237f9334e90a6f4d31ecf388e54
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/f29a16b67e354099b5b9e6344e5a8f50
Autor:
Amel Bekkar, Nathalie Isorce, Tiia Snäkä, Stéphanie Claudinot, Chantal Desponds, Dmitry Kopelyanskiy, Florence Prével, Marta Reverte, Ioannis Xenarios, Nicolas Fasel, Filipa Teixeira
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Leishmania RNA virus 1 (LRV1) is a double-stranded RNA virus found in some strains of the human protozoan parasite Leishmania, the causative agent of leishmaniasis, a neglected tropical disease. Interestingly, the presence of LRV1 inside Leishmania c
Externí odkaz:
https://doaj.org/article/181dfcd665c34ebf9676af69b98fa31b
Autor:
Dmitry Kopelyanskiy, Chantal Desponds, Florence Prevel, Matteo Rossi, Romain Migliorini, Tiia Snäkä, Remzi Onur Eren, Stéphanie Claudinot, Lon-Fye Lye, Manolis Pasparakis, Stephen M. Beverley, Nicolas Fasel
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Inducible nitric oxide synthase (iNOS) is essential to the production of nitric oxide (NO), an efficient effector molecule against intracellular human pathogens such as Leishmania protozoan parasites. Some strains of Leishmania are known to bear a vi
Externí odkaz:
https://doaj.org/article/c151bad224a24fb88b5d3c55d3e1da06
Autor:
Tiia Snäkä, Amel Bekkar, Chantal Desponds, Florence Prével, Stéphanie Claudinot, Nathalie Isorce, Filipa Teixeira, Coline Grasset, Ioannis Xenarios, Isabel C. Lopez-Mejia, Lluis Fajas, Nicolas Fasel
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Mitochondria regulate steroid hormone synthesis, and in turn sex hormones regulate mitochondrial function for maintaining cellular homeostasis and controlling inflammation. This crosstalk can explain sex differences observed in several pathologies su
Externí odkaz:
https://doaj.org/article/e3a5b453039340959dab9e3dc28b1dd5
Autor:
Marta Reverte, Remzi Onur Eren, Baijayanti Jha, Chantal Desponds, Tiia Snäkä, Florence Prevel, Nathalie Isorce, Lon-Fye Lye, Katherine L Owens, Ulisses Gazos Lopes, Stephen M Beverley, Nicolas Fasel
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009422 (2021)
The oxidative burst generated by the host immune system can restrict intracellular parasite entry and growth. While this burst leads to the induction of antioxidative enzymes, the molecular mechanisms and the consequences of this counter-response on
Externí odkaz:
https://doaj.org/article/0afbb9684d2240dd949e1accd28bc3af
Autor:
Tiia Snäkä, Nicolas Fasel
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Regulatory Nod-like receptors (NLRs) are a subgroup of the cytosolic NLR family of pathogen recognition receptors (PRRs). These receptors can tune the innate immune responses triggered by the activation of other PRRs by either augmenting or attenuati
Externí odkaz:
https://doaj.org/article/0dd9a93d40c14706b22b1cd650636073
Publikováno v:
Pathogens, Vol 11, Iss 4, p 409 (2022)
Leishmania parasites preferentially invade macrophages, the professional phagocytic cells, at the site of infection. Macrophages play conflicting roles in Leishmania infection either by the destruction of internalized parasites or by providing a safe
Externí odkaz:
https://doaj.org/article/5624272d767a4ca89f7a9dbc18cdfa0e
Publikováno v:
Pathogens. 11:409
Leishmania parasites preferentially invade macrophages, the professional phagocytic cells, at the site of infection. Macrophages play conflicting roles in Leishmania infection either by the destruction of internalized parasites or by providing a safe
Autor:
Marta Reverte, Remzi Onur Eren, Baijayanti Jha, Chantal Desponds, Tiia Snäkä, Florence Prevel, Nathalie Isorce, Lon-Fye Lye, Katherine L Owens, Ulisses Gazos Lopes, Stephen M Beverley, Nicolas Fasel
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 3, p e1009422 (2021)
PLoS Pathogens, Vol 17, Iss 3, p e1009422 (2021)
The oxidative burst generated by the host immune system can restrict intracellular parasite entry and growth. While this burst leads to the induction of antioxidative enzymes, the molecular mechanisms and the consequences of this counter-response on