Výsledky vyhledávání - "Tigran K. Davtyan"

Akademický článek

Development and Validation of Simple RP-HPLC Method for Intracellular Determination of Fluconazole Concentration and Its Application to the Study of Candida albicans Azole Resistance

Autor: Tigran K. Davtyan, Levon A. Melikyan, Nune A. Nikoyan, Hripsime P. Aleksanyan, Nairi G. Grigoryan

Publikováno v: International Journal of Analytical Chemistry, Vol 2015 (2015)

Candida albicans (strains NCTC-885-653 and ATCC-10231) long-term cultivated in the presence of antifungal agent fluconazole (FLC) and classical microbiological methods for determination of minimal inhibitory concentration (MIC) were used in this stud

Externí odkaz: https://doaj.org/article/ddd5af2a5094408591acc420e6dde34a

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Toll like receptors TLR1/2, TLR6 and MUC5B as binding interaction partners with cytostatic proline rich polypeptide 1 in human chondrosarcoma

Autor: Karina Galoian, Inesa Sahakyan, A. A. Galoyan, Narine V. Tumasyan, Gor Chailyan, Tigran K. Davtyan, Amir Qureshi, Silva S. Abrahamyan, Alexandra Moran, Samvel Chailyan, Part Hik Patel, Gil Metser, Albert Lee

Publikováno v: International Journal of Oncology

Metastatic chondrosarcoma is a bone malignancy not responsive to conventional therapies; new approaches and therapies are urgently needed. We have previously reported that mTORC1 inhibitor, antitumorigenic cytostatic proline rich polypeptide 1 (PRP-1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0415e1c41a5a3b148b57495fd8ba2e8b
https://doi.org/10.3892/ijo.2017.4199

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The Effect of Antibiotic-Resistant and Sensitive Escherichia coli on theProduction of Pro-Inflammatory Cytokine Response by Human PeripheralBlood Mononuclear Cells

Autor: Sholpan K. Tursunova, Assima O. Abekova, Sabina G. Murzageldinova, Ilya S. Korotetskiy, Murat E. Kulmanov, Alexander Ilin, Zhansaya S. Abramova, Tigran K. Davtyan, Roza T. Kenzhebekova, Ardak B. Dzhumagazieva, Galina V. Volodina, Indira E. Bishimova

Publikováno v: Journal of Clinical & Cellular Immunology. 8

Purpose: A comparative study of the effect of Escherichia coli, differing in gentamicin sensitivity, on the production of human pro-inflammatory cytokines IL-1β, IL-6, TNF-α by human peripheral blood mononuclear cells (PBMC) was carried out to dete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fde8d7339b3adf3ed94d85eb27fb14f6
https://doi.org/10.4172/2155-9899.1000522

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Mutations in MEFV cause alterations in neutrophil F-actin and phagocytosis dynamics

Autor: Tigran K. Davtyan, Gagik Hakobyan, Samvel A. Avetisyan

Publikováno v: Biopolymers and Cell, Vol 27, Iss 5, Pp 354-358 (2011)

Aim. To examine neutrophil F-actin, phagocytosis and macropinocytosis dymanics in patients with Familial Mediterranean Fever (FMF), in an effort to understand the mechanisms that regulate switch of neutrophil activation program. Methods. Whole blood

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387b8b611a9a84644c5030cc5e1265c0
http://biopolymers.org.ua/archive/2011/05/07.pdf

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Hypothalamic Proline Rich Polypeptide Regulates Hematopoiesis

Autor: Kristina B. Bezirganyan, Tigran K. Davtyan, Armen A. Galoyan

Publikováno v: Neurochemical Research. 35:917-924

The AGAPEPAEPAQPGVY proline-rich polypeptide (PRP-1) was isolated from neurosecretory granules of the bovine neurohypophysis; it is produced by N. supraopticus and N. paraventricularis. It has been shown that PRP-1 has many potentially beneficial bio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54591b220125c4341c675a843ae1a2c4
https://doi.org/10.1007/s11064-009-0109-3

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Design of Iodine-Lithium-α-Dextrin Liquid Crystal with Potent Antimicrobial and Anti-Inflammatory Properties

Autor: Emil S. Gabrielyan, Tigran K. Davtyan, Levon M. Mkhitaryan

Publikováno v: Current Pharmaceutical Design. 15:1172-1186

An ideal antimicrobial should be not toxic and possess board spectrum antiviral, antibacterial, antifungal activity, excluding resistance and should affect pathogen-mediated damage of host physiology including immune, nervous and endocrine systems. W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3105f89b5ac9564d144fbabd3acc1b12
https://doi.org/10.2174/138161209787846829

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The 1F7 idiotype is selectively expressed on CD5 + B cells and elevated in chronic hepatitis C virus infection

Autor: Aiden Brazil, Geri Hirsch, Marine P Hovsepyan, Michael D. Grant, Kevork M. Peltekian, Tigran K. Davtyan, Gagik Hakobyan, Levon M. Mkhitaryan, Lisa Barrett

Publikováno v: Immunology & Cell Biology. 87:457-463

Antibodies against different chronic viruses, including hepatitis C virus (HCV), express a public cross-reactive idiotype (Id) designated as 1F7. The prominence of this Id may reflect selective engagement of B1 B cells by chronic pathogens. We invest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f13c7f4a5c623d2f108520bbac441187
https://doi.org/10.1038/icb.2009.18

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Effect of Hypothalamic Proline-Rich Peptide (PRP-1) on Neuronal and Bone Marrow Cell Apoptosis

Autor: Armen A. Galoyan, Susanne Klumpp, Josef Krieglstein, Wolfram Kremers, Kristina E. Danielian, Tigran K. Davtyan, Karine A. Galoian, Kristina B. Bezirganyan

Publikováno v: Neurochemical Research. 32:1898-1905

The AGAPEPAEPAQPGVY proline-rich peptide (PRP-1) was isolated from neurosecretory granules of the bovine neurohypophysis; it is produced by N. supraopticus and N. paraventricularis. It has been shown that PRP-1 has many potentially beneficial biologi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f219abd86d2133f5751eeecef5fb477
https://doi.org/10.1007/s11064-007-9379-9

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Evaluation of amino acids as mediators for the antibacterial activity of iodine-lithium-α-dextrin in vitro and in vivo

Autor: Isabelle S. Hakobyan, Hrachya Hovhannisyan, Rafael E. Muradyan, Emil S. Gabrielyan, Tigran K. Davtyan

Publikováno v: Journal of Antimicrobial Chemotherapy. 59:1114-1122

Objectives: The systemic therapeutic application of iodophores has not yet been accepted due to limited availability of safe and effective ionized iodine preparations. Here we evaluated the antibacterial activity of iodine-lithium-a-dextrin (ILaD) bo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18014a10e3e2b129313cf1b797cf5662
https://doi.org/10.1093/jac/dkm094

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Accelerated Apoptosis of Neutrophils in Familial Mediterranean Fever

Autor: Gagik Hakobyan, Gayane Manukyan, Tigran K. Davtyan, Rustam Aminov

Publikováno v: Frontiers in Immunology, Vol 6 (2015)
Frontiers in Immunology
Manukyan, G, Aminov, R, Hakobyan, G & Davtyan, T 2015, ' Accelerated apoptosis of neutrophils in familial Mediterranean fever ', Frontiers in Immunology, no. 6, 239 . https://doi.org/10.3389/fimmu.2015.00239

The causative mutations for familial Mediterranean fever (FMF) are located in the MEFV gene, which encodes pyrin. Pyrin modulates the susceptibility to apoptosis via its PYD domain but how the mutated versions of pyrin affect apoptotic processes is p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18eb33ecbfb2e48b4f97e8d82c2ef365
https://doi.org/10.3389/fimmu.2015.00239

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