Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tiffini Brabham"'
Autor:
J.-P. Valentin, William S. Redfern, Hugo M. Vargas, Michael K. Pugsley, Andrea Greiter-Wilke, Maxim Soloviev, Simon Authier, Tiffini Brabham, J.E. Koerner, Derek J. Leishman, Krystle Correll, Mike Engwall, Carrie Markgraf, Tomas Mow, Alfred Botchway, Martin Traebert
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 93:35-45
Safety Pharmacology studies are conducted to characterize the confidence by which biologically active new chemical entities (NCE) may be anticipated as safe. Non-clinical safety pharmacology studies aim to detect and characterize potentially undesira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7a6be467c3064fe91360a2aa6c71bf3
https://doi.org/10.1016/j.vascn.2018.01.001
https://doi.org/10.1016/j.vascn.2018.01.001
Autor:
Alfred Botchway, Simon Authier, Hugo M. Vargas, Derek J. Leishman, Andrea Greiter-Wilke, Maxim Soloviev, Michael J. Curtis, Michael K. Pugsley, Carrie G. Markgraf, Jean-Pierre Valentin, Tiffini Brabham, Krystle Correll, Martin Traebert
Publikováno v:
Journal of pharmacological and toxicological methods. 88(Pt 1)
Introduction Safety pharmacology is a growing discipline with scientists broadly distributed across international geographical regions. This electronic salary survey is the first to be distributed amongst the entire Safety Pharmacology Society (SPS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49183b524511943866e19df4ad3fe2fc
https://pubmed.ncbi.nlm.nih.gov/28797763
https://pubmed.ncbi.nlm.nih.gov/28797763
Autor:
Michael K. Pugsley, Simon Authier, William S. Redfern, Martin Traebert, Alfred Botchway, Derek J. Leishman, Tomas Mow, Tiffini Brabham, J.E. Koerner, Maxim Soloviev, J.-P. Valentin, Krystle Correll, Mike Engwall, Hugo M. Vargas, Andrea Greiter-Wilke, Carrie Markgraf
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 95:1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::add4e974e41dca7dce74703ca2d4a9bc
https://doi.org/10.1016/j.vascn.2018.09.003
https://doi.org/10.1016/j.vascn.2018.09.003
Autor:
Donald Hodges, Alfred W. Botchway, Martin Traebert, Tiffini Brabham, Malar Pannirselvam, Michael K. Pugsley
Publikováno v:
Journal of pharmacological and toxicological methods. 85
The Safety Pharmacology Society (SPS) held a Northeast (NE) regional meeting in Boston, MA on May 13, 2016 at the Vertex Pharmaceuticals Incorporated site. There were 103 attendees from the pharmaceutical industry, contract research organizations (CR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d99d3084d7b1b6ed6bda3b23192ae376
https://pubmed.ncbi.nlm.nih.gov/27913272
https://pubmed.ncbi.nlm.nih.gov/27913272
Autor:
Paul Brennan, Dominique Westbrook, Colleen P. Gibbons, Robin Ward, Carly L. Nichols, Michael R. Sutton, Mark Holbrook, Julian Blagg, Nicholas J. Edmunds, Alison Bridgeland, Tiffini Brabham, Kelly Conlon, Andrews Mark David, Peter J. Bungay, Gavin A. Whitlock, Alan S. Jessiman, Karin McIntosh, James Root, Martin P. Green, Gordon McMurray, R. Ian Storer, Paul V. Fish, Alan Daniel Brown, Giles Hanton, Kerry af Forselles
New pyrimido[4,5-d]azepines 7 are disclosed as potent 5-HT2C receptor agonists. A preferred example, 7b had minimal activation at either the 5-HT2A or 5-HT2B receptors combined with robust efficacy in a preclinical canine model of stress urinary inco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05dc5f0ff0edfc935edd8d293ee1e0da
https://doi.org/10.1016/j.bmcl.2010.11.120
https://doi.org/10.1016/j.bmcl.2010.11.120
Autor:
Tiffini Brabham, Derek J. Leishman, Alfred Botchway, Maxim Soloviev, Tomas Mow, Hugo M. Vargas, Simon Authier, Helen Prior, Carrie G. Markgraf, Krystle Correll, Michael K. Pugsley, Andrea Greiter-Wilke, Jean-Pierre Valentin, John Koerner, Michael J. Engwall, Martin Traebert, Will S. Redfern
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 88:246
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e3e67bbe896c72a8c2bf39f42f22f8e
https://doi.org/10.1016/j.vascn.2017.09.252
https://doi.org/10.1016/j.vascn.2017.09.252
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 279:R1899-R1909
The present study investigated the effect of prenatal dexamethasone (Dex) exposure on early perinatal events, hippocampal function, and response to stress. Pregnant rats received Dex in the evening water (2.5 μg/ml) or tap water (Veh) from gestation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a122ca099e14a0882db35da6636183ac
https://doi.org/10.1152/ajpregu.2000.279.5.r1899
https://doi.org/10.1152/ajpregu.2000.279.5.r1899
Autor:
Keri E. Cannon, Tiffini Brabham
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 64:e25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa1d7e5ba301f8ad2f3b4c3417dec82f
https://doi.org/10.1016/j.vascn.2011.03.091
https://doi.org/10.1016/j.vascn.2011.03.091
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 58:158
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f21b675ff19029fe32e837d84dcb757
https://doi.org/10.1016/j.vascn.2008.05.054
https://doi.org/10.1016/j.vascn.2008.05.054
Autor:
Jaime Monsere, Tiffini Brabham, Lonnie E. Grantham, Deborah Robinson, Terri Banchero, Genevieve Gagnon, Pedro Tan
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 56:e3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0f608ae3d78de8ba78033eb88005ce2
https://doi.org/10.1016/j.vascn.2007.02.007
https://doi.org/10.1016/j.vascn.2007.02.007