Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Tiffany-Jayne Allen"'
Autor:
Erika Harno, Charlotte Sefton, Jonathan R. Wray, Tiffany-Jayne Allen, Alison Davies, Anthony P. Coll, Anne White
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Glucocorticoids (GCs) are widely prescribed anti-inflammatory medicines, but their use can lead to metabolic side-effects. These may occur through direct actions of GCs on peripheral organs, but could also be mediated by the hypothalamic AgR
Externí odkaz:
https://doaj.org/article/454fb846197a4d86a1ee9dc8b94bc978
Autor:
Jonathan R. Wray, Alison Davies, Charlotte Sefton, Tiffany-Jayne Allen, Antony Adamson, Philip Chapman, Brian Y.H. Lam, Giles S.H. Yeo, Anthony P. Coll, Erika Harno, Anne White
Publikováno v:
Molecular Metabolism, Vol 26, Iss , Pp 5-17 (2019)
Objective: Glucocorticoids (GCs) are widely prescribed medications that are well recognized to cause adverse metabolic effects including hyperphagia, obesity, and hyperglycemia. These effects have been recapitulated in a murine model of GC excess, an
Externí odkaz:
https://doaj.org/article/15bf380476bb40b2a665b989ba63e358
Autor:
Jonathan R Wray, Anthony P. Coll, Alison Davies, Anne White, Tiffany-Jayne Allen, Erika Harno, Charlotte Sefton
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Funder: Mawer-Fitzgerald Endowment Fund
Glucocorticoids (GCs) are widely prescribed anti-inflammatory medicines, but their use can lead to metabolic side-effects. These may occur through direct actions of GCs on peripheral organs, but could also
Glucocorticoids (GCs) are widely prescribed anti-inflammatory medicines, but their use can lead to metabolic side-effects. These may occur through direct actions of GCs on peripheral organs, but could also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05273b92ec74ca2d8510d000326c8f90
Autor:
Rosemary Shoop, Neil E. Humphreys, Charlotte Sefton, Anne White, Tiffany-Jayne Allen, Alison Davies, Antony Adamson, Erika Harno, Jonathan R Wray, Anthony P. Coll
Publikováno v:
Endocrinology
Glucocorticoids are potent and widely used medicines but often cause metabolic side effects. A murine model of corticosterone treatment resulted in increased hypothalamic expression of the melanocortin antagonist AgRP in parallel with obesity and hyp
Autor:
Roben G. Gieling, Tiffany-Jayne Allen, Claudiu T. Supuran, Suzanne Meredith, Jennifer L. Bryant, Brian A. Telfer, Kaye J. Williams, Leanne Walker, Anne White
Publikováno v:
International Journal of Cancer. 142:191-201
Small cell lung cancer (SCLC) has an extremely poor prognosis and methods of improving chemotherapeutic intervention are much sought after. A promising approach lies in inhibiting the tumour-associated enzyme, carbonic anhydrase IX (CA IX), which sup
Autor:
Anthony P. Coll, Erika Harno, Charlotte Sefton, Jonathan R Wray, Anne White, Tiffany-Jayne Allen, Alison Davies
Publikováno v:
Endocrine Abstracts.
Autor:
Jonathan R Wray, Anthony P. Coll, Alison Davies, Anne White, Erika Harno, Tiffany-Jayne Allen, Charlotte Sefton
Publikováno v:
Endocrine Abstracts.
Autor:
Anne White, Alison Davies, Tiffany-Jayne Allen, Charlotte Sefton, Thanuja Gali Ramamoorthy, Erika Harno, Chris Murgatroyd
Publikováno v:
Gali Ramamoorthy, T, Allen, T-J, Davies, A, Harno, E, Sefton, C, Murgatroyd, C & White, A 2018, ' Maternal overnutrition programs epigenetic changes in the regulatory regions of hypothalamic Pomc in the offspring of rats ', International Journal of Obesity . https://doi.org/10.1038/s41366-018-0094-1
International Journal of Obesity (2005)
International Journal of Obesity (2005)
Background and objectiveMaternal overnutrition has been implicated in affecting the offspring by programming metabolic disorders such as obesity and diabetes, by mechanisms that are not clearly understood. This study aimed to determine the long-term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e760889999988b2e0d619ab16ef2a68
https://www.research.manchester.ac.uk/portal/en/publications/maternal-overnutrition-programs-epigenetic-changes-in-the-regulatory-regions-of-hypothalamic-pomc-in-the-offspring-of-rats(fcc0aced-b917-414b-aaf7-a9edfad65b39).html
https://www.research.manchester.ac.uk/portal/en/publications/maternal-overnutrition-programs-epigenetic-changes-in-the-regulatory-regions-of-hypothalamic-pomc-in-the-offspring-of-rats(fcc0aced-b917-414b-aaf7-a9edfad65b39).html
Autor:
Jennifer L, Bryant, Roben G, Gieling, Suzanne L, Meredith, Tiffany-Jayne, Allen, Leanne, Walker, Brian A, Telfer, Claudiu T, Supuran, Kaye J, Williams, Anne, White
Publikováno v:
International journal of cancer. 142(1)
Small cell lung cancer (SCLC) has an extremely poor prognosis and methods of improving chemotherapeutic intervention are much sought after. A promising approach lies in inhibiting the tumour-associated enzyme, carbonic anhydrase IX (CA IX), which sup
Elevated Hypothalamic Glucocorticoid Levels Are Associated With Obesity and Hyperphagia in Male Mice
Autor:
Jonathan R Wray, Helen Small, Erika Harno, Anthony P. Coll, Catherine B. Lawrence, Charlotte Sefton, Anne White, Alison Davies, Tiffany-Jayne Allen
Publikováno v:
Sefton, C, Harno, E, Davies, A, Small, H, Allen, T-J, Wray, J, Lawrence, C, Coll, A P & White, A 2016, ' Elevated hypothalamic glucocorticoid levels are associated with obesity and hyperphagia in male mice. ', Endocrinology, vol. 157, no. 11, pp. 4257-4265 . https://doi.org/10.1210/en.2016-1571
Endocrinology
Endocrinology
Glucocorticoid (Gc) excess, from endogenous overproduction in disorders of the hypothalamic-pituitary-adrenal axis or exogenous medical therapy, is recognized to cause adverse metabolic side effects. The Gc receptor (GR) is widely expressed throughou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96bacc5ac5376b513b1343fdc815e5d