Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Tiffany Zhang"'
Autor:
Abdelfattah Faouzi, Haoqing Wang, Saheem A. Zaidi, Jeffrey F. DiBerto, Tao Che, Qianhui Qu, Michael J. Robertson, Manish K. Madasu, Amal El Daibani, Balazs R. Varga, Tiffany Zhang, Claudia Ruiz, Shan Liu, Jin Xu, Kevin Appourchaux, Samuel T. Slocum, Shainnel O. Eans, Michael D. Cameron, Ream Al-Hasani, Ying Xian Pan, Bryan L. Roth, Jay P. McLaughlin, Georgios Skiniotis, Vsevolod Katritch, Brian K. Kobilka, Susruta Majumdar
Publikováno v:
Nature.
Mu opioid receptor (µOR) agonists like fentanyl have long been used for pain management, but are considered a major public health concern due to their adverse side effects, including lethal overdose.
Publikováno v:
Journal of Student Research. 11
Dilated cardiomyopathy (DCM), the most common cardiomyopathy, is characterized by ventricular dilation and impaired heart contractility. Past studies found that the inhibition of the ubiquitin-proteasome system (UPS), a crucial protein degradation sy
Autor:
Bing Xie, Valerie P. Le Rouzic, Alexander Goldberg, Meng-Hua M. Tsai, Li Chen, Tiffany Zhang, Antara Sinha, Ying-Xian Pan, Michael H. Baumann, Lei Shi
Publikováno v:
Neuropharmacology. 227:109442
Autor:
Abdelfattah Faouzi, Hye Jean Yoon, Rajendra Uprety, John M. Streicher, Lakshmi A. Devi, Susruta Majumdar, Michael Ansonoff, Ivone Gomes, Nicolas Massaly, Tiffany Zhang, Valerie Le Rouzic, Attila Keresztes, Jose A. Morón, Ying-Xian Pan, Achla Gupta, Abdullah Allaoa, John E. Pintar
Publikováno v:
J Med Chem
In this work, we studied a series of carfentanyl amide-based opioid derivatives targeting the mu opioid receptor (μOR) and the delta opioid receptor (δOR) heteromer as a credible novel target in pain management therapy. We identified a lead compoun
Publikováno v:
Mol Pharmacol
The μ-opioid receptor gene undergoes extensive alternative splicing to generate an array of splice variants. One group of splice variants excludes the first transmembrane (TM) domain and contains six TM domains. These 6TM variants are essential for
Autor:
Tiffany Zhang, Teng, Abdoul Habib, Beavogui, Bassirou, Diarra, Alexandre, Delamou, Jane, Holl, Almoustapha Issiaka, Maiga, Yeya Dit, Sadio Sarro, Amadou, Kone, Bourahima, Kone, Djeneba Bocar, Fofana, Etienne, Dembele, Mamadou Saliou, Sow, Moussa, Seydi, Aboubacar Alassane, Oumar, Mahamadou, Diakité, Souleymane, Diallo, Seydou, Doumbia, Sounkalo, Dao, Robert L, Murphy, Mamoudou, Maiga
Publikováno v:
Infect Dis Diagn Treat
The 2014-2016 Ebola epidemic in Guinea highlighted the need for more extensive evaluation of laboratories diagnostic capacities and preparedness in anticipation of future emerging viral disease outbreaks. We developed a questionnaire to assess the di
Autor:
Pathiraja A. Gunatillake, Katherine E. S. Locock, Lewis D. Blackman, Peter Cass, Yue Qu, Tiffany Zhang
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Inspired by the interesting natural antimicrobial properties of honey, biohybrid composite materials containing a low-fouling polymer hydrogel network and an encapsulated antimicrobial peroxide-producing enzyme have been developed. These synergistica
Publikováno v:
Journal of Applied Toxicology. 38:968-977
The kidney plays a major part in the elimination of many drugs and their metabolites, and drug-induced kidney injury commonly alters either glomerular filtration or tubular transport, or both. However, the renal excretion pathway of drugs has not bee
Publikováno v:
Biopharmaceutics & Drug Disposition. 37:511-521
Drug interactions are one of the commonest causes of side effects, particularly in long-term therapy. The aim of the current study was to investigate the possible effects of metoprolol on the pharmacokinetics of metformin in rats and to clarify the m
Autor:
Tao Che, Saheem A. Zaidi, Jay P. McLaughlin, Chloe A. Simons, Abdelfattah Faouzi, Susruta Majumdar, Ivy F Carroll, Manish K. Madasu, Ying-Xian Pan, Tiffany Zhang, Vsevolod Katritch, Chad Kormos, Bryan L. Roth, Shainnel O. Eans, Ream Al Hassani
Publikováno v:
The FASEB Journal. 34:1-1