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Autor:
Tiffany W. Grooms-Williams, Krystal Teasley Hamorsky, Nobuyuki Matoba, Lauren J. Bennett, Kenneth E. Palmer, Adam S. Husk
Publikováno v:
Antimicrobial Agents and Chemotherapy. 57:2076-2086
Broadly neutralizing monoclonal antibodies (bnMAbs) may offer powerful tools for HIV-1 preexposure prophylaxis, such as topical microbicides. However, this option is hampered due to expensive MAb biomanufacturing based on mammalian cell culture. To a