Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tiffany V Lin"'
Autor:
Antonia L Dow, Tiffany V Lin, Elena H Chartoff, David Potter, Donna L McPhie, Ashlee V Van't Veer, Allison T Knoll, Kristen N Lee, Rachael L Neve, Tarun B Patel, Dost Ongur, Bruce M Cohen, William A Carlezon
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120693 (2015)
Both the development and relief of stress-related psychiatric conditions such as major depression (MD) and post-traumatic stress disorder (PTSD) have been linked to neuroplastic changes in the brain. One such change involves the birth of new neurons
Externí odkaz:
https://doaj.org/article/fdc7b7c3b91f4cca82e12fe6c3b536f8
Autor:
Manavendra Pathania, Juan Torres-Reveron, Lily Yan, Tomoki Kimura, Tiffany V Lin, Valerie Gordon, Zhao-Qian Teng, Xinyu Zhao, Tudor A Fulga, David Van Vactor, Angélique Bordey
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e38174 (2012)
An array of signals regulating the early stages of postnatal subventricular zone (SVZ) neurogenesis has been identified, but much less is known regarding the molecules controlling late stages. Here, we investigated the function of the activity-depend
Externí odkaz:
https://doaj.org/article/a26b8ddce4cd42a796ec90b57fecf1b5
Publikováno v:
Cells, Vol 10, Iss 3, p 622 (2021)
Rab27a is an evolutionarily conserved small GTPase that regulates vesicle trafficking, and copy number variants of RAB27a are associated with increased risk of autism. However, the function of Rab27a on brain development is unknown. Here, we identifi
Externí odkaz:
https://doaj.org/article/ad696f955a3d42bc9cb290e8534378e2
Autor:
Heather A. Born, Lena H. Nguyen, Youfen Xu, Travorn Mahadeo, Angélique Bordey, Tiffany V. Lin, Anne E. Anderson, Longbo Zhang
Publikováno v:
Brain
Hyperactivation of the mTOR pathway during foetal neurodevelopment alters neuron structure and function, leading to focal malformation of cortical development and intractable epilepsy. Recent evidence suggests a role for dysregulated cap-dependent tr
Publikováno v:
J Neurosci
The release of small extracellular vesicles (sEVs) has recently been reported, but knowledge of their function in neuron development remains limited. Using LC-MS/MS, we found that sEVs released from developing cortical neuronsin vitroobtained from mi
Autor:
Anne E. Anderson, Lena H. Nguyen, Heather A. Born, Youfen Xu, Angélique Bordey, Longbo Zhang, Travorn Mahadeo, Tiffany V. Lin
SUMMARYHyperactivation of mTOR signaling during fetal neurodevelopment alters neuron structure and function, leading to focal malformation of cortical development (FMCD) and intractable epilepsy. Recent evidence suggests increased cap-dependent trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a83f14f81da71f9fe3125bff379ad72
https://doi.org/10.1101/2021.06.04.445850
https://doi.org/10.1101/2021.06.04.445850
Autor:
Tianxiang Huang, Angélique Bordey, Tiffany V. Lin, Matthew R. Sarkisian, Longbo Zhang, Xuan Gong, Lena H. Nguyen, Joshua J. Breunig, Gi Bum Kim
Publikováno v:
Neurosci Res
We combined translating ribosome affinity purification (TRAP) with in utero electroporation (IUE), called iTRAP to identify the molecular profile of specific neuronal populations during neonatal development without the need for viral approaches and F
Publikováno v:
Cells
Volume 10
Issue 3
Cells, Vol 10, Iss 622, p 622 (2021)
Volume 10
Issue 3
Cells, Vol 10, Iss 622, p 622 (2021)
Rab27a is an evolutionarily conserved small GTPase that regulates vesicle trafficking, and copy number variants of RAB27a are associated with increased risk of autism. However, the function of Rab27a on brain development is unknown. Here, we identifi
Autor:
John H. Wen, Angélique Bordey, Tiffany V. Lin, Longbo Zhang, Xuan Gong, Lawrence S. Hsieh, Laura Miyares, Tianxiang Huang
Publikováno v:
Human Molecular Genetics. 24:5746-5758
Abnormal axonal connectivity and hyperactive mTOR complex 1 (mTORC1) are shared features of several neurological disorders. Hyperactive mTORC1 alters axon length and polarity of hippocampal neurons in vitro, but the impact of hyperactive mTORC1 on ax
Autor:
David M. Feliciano, Longbo Zhang, Angélique Bordey, Nathaniel W. Hartman, Tiffany V. Lin, Grace E. Paquelet
Publikováno v:
Cell Reports, Vol 5, Iss 2, Pp 433-444 (2013)
SummaryThe mammalian target of rapamycin complex 1 (mTORC1) integrates signals important for cell growth, and its dysregulation in neural stem cells (NSCs) is implicated in several neurological disorders associated with abnormal neurogenesis and brai