Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tiffany Telarico"'
Autor:
Andras Perl, Igor Dozmorov, Henry V. Baker, Daniel J. Perry, Laurence Morel, Tiffany Telarico, Yiming Yin
Publikováno v:
The Journal of Immunology. 189:793-803
Sle1c is a sublocus of the NZM2410-derived Sle1 major lupus susceptibility locus. We have shown previously that Sle1c contributes to lupus pathogenesis by conferring increased CD4+ T cell activation and increased susceptibility to chronic graft-versu
Publikováno v:
Current Opinion in Rheumatology. 22:483-492
Purpose of review Genetic and environmental factors influence the development of systemic lupus erythematosus (SLE). Endogenous retroviruses (ERVs) are proposed as a molecular link between the human genome and environmental factors, such as viruses,
Autor:
Werner Müller-Esterl, Andras Perl, Eduardo Bonilla, Stefanie Oess, David Fernandez, Paul E. Phillips, Frank A. Middleton, Mary K. Crow, Sanjay K. Banerjee, Tiffany Telarico, Qing Li
Publikováno v:
The Journal of Immunology. 182:2063-2073
Persistent mitochondrial hyperpolarization (MHP) and enhanced calcium fluxing underlie aberrant T cell activation and death pathway selection in systemic lupus erythematosus. Treatment with rapamycin, which effectively controls disease activity, norm
Autor:
David Fernandez, György Nagy, Tiffany Telarico, Agnes Koncz, Paul E. Phillips, Péter Gergely, Eduardo Bonilla, Edward Doherty, Andras Perl
Publikováno v:
Autoimmunity. 41:287-297
Genetic and environmental factors are believed to influence development of systemic lupus erythematosus (SLE). Endogenous retroviruses (ERV) correspond to the integrated proviral form of infectious retroviruses, which are trapped within the genome du
Autor:
Katalin Banki, Andras Perl, Yueming Qian, Dick D. Mosser, Péter Gergely, Agnes Koncz, Jeffrey P. Ward, Brian Niland, David Fernandez, Craig E. Grossman, György Nagy, Tiffany Telarico, Christina Stancato
Publikováno v:
Journal of Biological Chemistry. 281:34574-34591
A novel 2986-base transcript encoded by the antisense strand of the HRES-1 human endogenous retrovirus was isolated from peripheral blood lymphocytes. This transcript codes for a 218-amino acid protein, termed HRES-1/Rab4, based on homology to the Ra
Autor:
Tiffany, Telarico, Andras, Perl
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 900
Abnormalities in T cell signal transduction underlie pathology in systemic lupus erythematosus. Lupus T cells are more sensitive to stimulation, yet have reduced expression of T cell antigen receptor (TCR) at the surface. The amount of TCR expressed
Autor:
Andras Perl, Tiffany Telarico
Publikováno v:
Methods in Molecular Biology ISBN: 9781607617198
Abnormalities in T cell signal transduction underlie pathology in systemic lupus erythematosus. Lupus T cells are more sensitive to stimulation, yet have reduced expression of T cell antigen receptor (TCR) at the surface. The amount of TCR expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::116d24786c5c94c2a8ebe0b8fd84e97d
https://doi.org/10.1007/978-1-60761-720-4_5
https://doi.org/10.1007/978-1-60761-720-4_5
Publikováno v:
Trends in molecular medicine. 17(7)
Metabolism of glucose through the pentose phosphate pathway (PPP) influences the development of diverse pathologies. Hemolytic anemia due to deficiency of PPP enzyme glucose 6-phosphate dehydrogenase is the most common genetic disease in humans. Rece
Autor:
David Fernandez, Edit I. Buzás, Agnes Koncz, György Nagy, Tiffany Telarico, Barbara Érsek, Andras Perl
Publikováno v:
Arthritis Research & Therapy
Nitric oxide (NO) has been shown to regulate T cell functions under physiological conditions, but overproduction of NO may contribute to T lymphocyte dysfunction. NO-dependent tissue injury has been implicated in a variety of rheumatic diseases, incl
Autor:
David Fernandez, Edward Doherty, Tiffany Telarico, Lisa Francis, Paul E. Phillips, Andras Perl
Systemic lupus erythematosus is characterized by the production of antinuclear autoantibodies and dysfunction of T-cells, B-cells, and dendritic cells. Here, we review newly recognized genetic factors and mechanisms that underlie abnormal intracellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1bb8023a7e61f5bb185f9edc2eb6405
https://europepmc.org/articles/PMC4047522/
https://europepmc.org/articles/PMC4047522/