Zobrazeno 1 - 10 of 34 pro vyhledávání: '"Tiffany T Chu"'
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Akademický článek
Protease-activated receptor 4 activity promotes platelet granule release and platelet-leukocyte interactions
Autor: Rachel A. Rigg, Laura D. Healy, Tiffany T. Chu, Anh T. P. Ngo, Annachiara Mitrugno, Jevgenia Zilberman-Rudenko, Joseph E. Aslan, Monica T. Hinds, Lisa Dirling Vecchiarelli, Terry K. Morgan, András Gruber, Kayla J. Temple, Craig W. Lindsley, Matthew T. Duvernay, Heidi E. Hamm, Owen J. T. McCarty
Publikováno v: Platelets, Vol 30, Iss 1, Pp 126-135 (2019)
Human platelets express two protease-activated receptors (PARs), PAR1 (F2R) and PAR4 (F2RL3), which are activated by a number of serine proteases that are generated during pathological events and cause platelet activation. Recent interest has focused
Externí odkaz: https://doaj.org/article/6960b5c705204591a63ac3d50fe5f52c
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2
Activated protein C inhibits neutrophil extracellular trap formation in vitro and activation in vivo
Autor: José A. Fernández, Florea Lupu, Tiffany T. Chu, Laura D. Healy, Nyiawung A. Taku, John H. Griffin, Ravi S. Keshari, Cristina Puy, Andras Gruber, Xiao Xu, Annachiara Mitrugno, Owen J. T. McCarty
Publikováno v: Journal of Biological Chemistry. 292:8616-8629
Activated protein C (APC) is a multifunctional serine protease with anticoagulant, cytoprotective, and anti-inflammatory activities. In addition to the cytoprotective effects of APC on endothelial cells, podocytes, and neurons, APC cleaves and detoxi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::05773b0a926460e6e704431d0e57fdc6
https://doi.org/10.1074/jbc.m116.768309
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5
Activated protein C inhibits neutrophil extracellular trap formation
Autor: Laura D, Healy, Cristina, Puy, José A, Fernández, Annachiara, Mitrugno, Ravi S, Keshari, Nyiawung A, Taku, Tiffany T, Chu, Xiao, Xu, András, Gruber, Florea, Lupu, John H, Griffin, Owen J T, McCarty
Publikováno v: The Journal of biological chemistry. 292(21)
Activated protein C (APC) is a multifunctional serine protease with anticoagulant, cytoprotective, and anti-inflammatory activities. In addition to the cytoprotective effects of APC on endothelial cells, podocytes, and neurons, APC cleaves and detoxi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4f36f35406d6b226ec5ec80ba920bf18
https://pubmed.ncbi.nlm.nih.gov/28408624
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6
Structural characterization of the α-mating factor prepro-peptide for secretion of recombinant proteins in Pichia pastoris
Autor: Jason A. Catolico, Pachai Moua, Yu Fang Tina Tsai, Liang Xue, Janet Kwon, Zill-E-Huma Khan, Nadia Shaheen, Sabreen Chahal, Joan Lin-Cereghino, Geoff P. Lin-Cereghino, Jerry W. Tsai, Hyun Joo, Peter Wei, Vivian Tam, Sung Pil James Park, Anthony T. Vu, Tiffany T. Chu, Arth Patel
Publikováno v: Gene. 598
The methylotrophic yeast Pichia pastoris has been used extensively for expressing recombinant proteins because it combines the ease of genetic manipulation, the ability to provide complex posttranslational modifications and the capacity for efficient
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02949ea0c8eb426fdfaaa47f0954223d
https://pubmed.ncbi.nlm.nih.gov/27984193
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7
Colocalization of neutrophils, extracellular DNA and coagulation factors during NETosis: development and utility of an immunofluorescence-based microscopy platform
Autor: David K. Robinson, Cristina Puy, Tiffany T. Chu, Laura D. Healy, Owen J. T. McCarty, Alan Bylund, Elizabeth E. Gardiner, Kevin G. Phillips, Asako Itakura
Background Neutrophils, the most populous innate immune cell type, are the first responders to sites of infection and inflammation. Neutrophils can release their DNA to form extracellular traps (NETs), webs of DNA and granular proteases that contribu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ad5180ddeec833283e8b64805f2d9c
https://europepmc.org/articles/PMC4935600/
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8
Abstract 592: Rapamycin Increases the Thrombogenic Potential of Neutrophil Extracellular Traps (NETs): Potential Mechanism of Prothrombotic Drug-Eluting Stents
Autor: D. K Robinson, Laura D Healy, Tiffany T Chu, Heidi Oldenkamp, Christina Garcia Puy, András Gruber, Owen J McCarty
Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 35
Background: Neutrophil leukocytes are considered among the first cellular responders to bacterial host tissue infection. At sites of inflammation, neutrophils can undergo activation, releasing their nuclear content by freeing hydrolases from lysosome
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37903adbfe03210e9e025e71812ec2d5
https://doi.org/10.1161/atvb.35.suppl_1.592
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9
Akademický článek
Senolytic therapy preserves blood-brain barrier integrity and promotes microglia homeostasis in a tauopathy model.
Autor: Yao M; Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of medicine, Baltimore, MD, USA., Wei Z; The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Nielsen JS; The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Ouyang Y; Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of medicine, Baltimore, MD, USA., Kakazu A; Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of medicine, Baltimore, MD, USA., Wang H; Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of medicine, Baltimore, MD, USA., Du L; Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of medicine, Baltimore, MD, USA., Li R; Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of medicine, Baltimore, MD, USA., Chu T; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Scafidi S; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Lu H; The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Aggarwal M; The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Duan W; Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of medicine, Baltimore, MD, USA; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: wduan2@jhmi.edu.
Publikováno v: Neurobiology of disease [Neurobiol Dis] 2024 Nov; Vol. 202, pp. 106711. Date of Electronic Publication: 2024 Oct 21.
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10
Publisher Correction: Generation of 'semi-guided' cortical organoids with complex neural oscillations.
Autor: Fitzgerald MQ; Department of Bioengineering, University of California San Diego, San Diego, CA, USA.; Department of Pediatrics, University of California San Diego, San Diego, CA, USA., Chu T; Department of Pediatrics, University of California San Diego, San Diego, CA, USA.; Department of Cellular and Molecular Medicine, University of California San Diego, San Diego, CA, USA., Puppo F; Department of Pediatrics, University of California San Diego, San Diego, CA, USA.; Department of Cellular and Molecular Medicine, University of California San Diego, San Diego, CA, USA., Blanch R; Department of Pediatrics, University of California San Diego, San Diego, CA, USA.; Institut de Recerca Vall d'Hebron and Institut de Neurociències, Biochemistry and Molecular Biology Department, Universitat Autònoma de Barcelona, Barcelona, Spain., Chillón M; Institut de Recerca Vall d'Hebron and Institut de Neurociències, Biochemistry and Molecular Biology Department, Universitat Autònoma de Barcelona, Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats, Barcelona, Spain., Subramaniam S; Department of Bioengineering, University of California San Diego, San Diego, CA, USA.; Department of Cellular and Molecular Medicine, University of California San Diego, San Diego, CA, USA.; Department of Computer Science and Engineering, University of California San Diego, San Diego, CA, USA., Muotri AR; Department of Pediatrics, University of California San Diego, San Diego, CA, USA. muotri@ucsd.edu.; Department of Cellular and Molecular Medicine, University of California San Diego, San Diego, CA, USA. muotri@ucsd.edu.; Center for Academic Research and Training in Anthropogeny and Archealization, University of California San Diego, La Jolla, CA, USA. muotri@ucsd.edu.; Sanford Stem Cell Education and Integrated Space Stem Cell Orbital Research Center, Sanford Stem Cell Institute, University of California San Diego, La Jolla, CA, USA. muotri@ucsd.edu.
Publikováno v: Nature protocols [Nat Protoc] 2024 Oct 15. Date of Electronic Publication: 2024 Oct 15.
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