Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tiffany Scully"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Expression of the low-density lipoprotein receptor (LDLR) has been shown to play a critical role in hypercholesterolemia-associated breast cancer growth and is associated with shorter recurrence-free survival in human breast cancer studies.
Externí odkaz:
https://doaj.org/article/4637f21548d947e5b1af8ade15841430
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Obesity and type 2 diabetes have both been associated with increased cancer risk and are becoming increasingly prevalent. Metabolic abnormalities such as insulin resistance and dyslipidemia are associated with both obesity and type 2 diabetes and hav
Externí odkaz:
https://doaj.org/article/0937af9bbfda43bdbf2d23f3c2d04153
Publikováno v:
Endocrine-Related Cancer. 30
Tumor uptake of exogenous cholesterol has been associated with the proliferation of various cancers. Previously, we and others have shown that hypercholesterolemia promotes tumor growth and silencing of the LDL receptor (LDLR) in high LDLR-expressing
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Expression of the low-density lipoprotein receptor (LDLR) has been shown to play a critical role in hypercholesterolemia-associated breast cancer growth and is associated with shorter recurrence-free survival in human breast cancer studies. We sought
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 10 (2021)
Frontiers in Oncology, Vol 10 (2021)
Obesity and type 2 diabetes have both been associated with increased cancer risk and are becoming increasingly prevalent. Metabolic abnormalities such as insulin resistance and dyslipidemia are associated with both obesity and type 2 diabetes and hav
Autor:
Abora Ettela, Irwin J. Kurland, Nathan Kase, Yunping Qiu, Annie James, Chifei Kang, Tiffany Scully, Irini Markella Antoniou, Evren U. Azeloglu, Emily J. Gallagher, Nicholas J. Wong
Publikováno v:
Journal of the Endocrine Society
Obesity is associated with increased cancer risk and cancer-associated mortality1,2. Hypertriglyceridemia (HTG), a component of the metabolic syndrome which frequently co-exists with obesity, has been associated with increased breast cancer risk and
Autor:
Derek LeRoith, Irini Markella Antoniou, Nathan Kase, Tiffany Scully, Emily J. Gallagher, Chifei Kang, Gadi Shlomai, Abora Ettela, Annie James, Teresa L. Wood
Publikováno v:
Journal of the Endocrine Society
Systemic hyperinsulinemia is believed to be an important factor in the progression of a number of cancers, including breast cancer by activating the insulin receptor (IR) signaling cascade in the tumor cells. The IR is expressed in two isoforms, IR-A
Publikováno v:
Journal of the Endocrine Society
Preclinical models and clinical studies suggest that hypercholesterolemia promotes breast cancer progression 1,2. The expression of the low-density lipoprotein receptor (LDLR) has been positively associated with poorer recurrence-free survival in hum
Autor:
Robert C. Baxter, John E. Pintar, Sue M. Firth, Tiffany Scully, Tailoi Chan-Ling, Carolyn D. Scott, Stephen M. Twigg, Hasanthi C. de Silva
Publikováno v:
Oncotarget
// Tiffany Scully 1 , Sue M. Firth 1 , Carolyn D. Scott 1 , Hasanthi C. de Silva 1 , John E. Pintar 2 , Tailoi Chan-Ling 3 , Stephen M. Twigg 4 , Robert C. Baxter 1 1 Hormones and Cancer Laboratories, Kolling Institute, University of Sydney, Royal No
Autor:
Robert C. Baxter, Carolyn D. Scott, Sue M. Firth, Stephen M. Twigg, Tiffany Scully, John E. Pintar
Publikováno v:
Experimental cell research. 374(1)
IGFBP-3 has both stimulatory and inhibitory effects on cancer progression. The growth of EO771 mammary carcinoma cells as syngeneic tumors in C57BL/6 mice is reduced in Igfbp3-null (BP3KO) mice, suggesting that systemic IGFBP-3 enhances tumor progres