Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Tiffany R. Emmons"'
Publikováno v:
Molecular & Cellular Oncology, Vol 9, Iss 1 (2022)
Inducing immunogenic tumor cell death to stimulate the response to immune checkpoint blockade has not yet been effectively translated into clinical practice. We recently discovered that stressed/injured but still viable tumor cells are critical for T
Externí odkaz:
https://doaj.org/article/16b9badbd14c48bc8d2facda7cd7ee42
Autor:
Emad Y. Alqassim, Shraddha Sharma, A. N. M. Nazmul H. Khan, Tiffany R. Emmons, Eduardo Cortes Gomez, Abdulrahman Alahmari, Kelly L. Singel, Jaron Mark, Bruce A. Davidson, A. J. Robert McGray, Qian Liu, Brian D. Lichty, Kirsten B. Moysich, Jianmin Wang, Kunle Odunsi, Brahm H. Segal, Bora E. Baysal
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Alqassim et al find that RNA editing, known to be induced by IFN-1 in macrophages by the enzyme APOBEC3A, is required for the transcriptional, pro-inflammatory and metabolic responses that drive M1 macrophage polarization. APOBEC3A-mediated editing i
Externí odkaz:
https://doaj.org/article/8289df36f80e4288872e7c05d2e770f3
Autor:
Ingred Goretti Riça, Brian A. Joughin, Martha E. Teke, Tiffany R. Emmons, Alec M. Griffith, Laura A. Cahill, Valerie M. Banner-Goodspeed, Simon C. Robson, Jonathan M. Hernandez, Brahm H. Segal, Leo E. Otterbein, Carl J. Hauser, James A. Lederer, Michael B. Yaffe
Publikováno v:
Journal of Trauma and Acute Care Surgery. 94:187-196
Autor:
Brahm H. Segal, Emese Zsiros, Michael B. Yaffe, Kunle Odunsi, Kirsten B. Moysich, Kevin H. Eng, James A. Lederer, Sanjay Ram, Steven M. Holland, Jörg Eder, Holger Sellner, Anna Schubart, Viviana P. Ferreira, Lee-Ann H. Allen, Ilse Jongerius, Taco W. Kuijpers, Sora Suzuki, Mieke C. Brouwer, Cathelijn E.M. Aarts, Ivy L. Debreceni, Stephanie L. Silva-Del Toro, Kaitlyn Howard, Jason Ricciuti, ANM Nazmul H. Khan, Kelly L. Singel, Thejaswini Giridharan, Tiffany R. Emmons
Supplementary Tables 1-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a13f6bea6ac0d91539043db8f72237
https://doi.org/10.1158/2326-6066.22543195
https://doi.org/10.1158/2326-6066.22543195
Autor:
Brahm H. Segal, Emese Zsiros, Michael B. Yaffe, Kunle Odunsi, Kirsten B. Moysich, Kevin H. Eng, James A. Lederer, Sanjay Ram, Steven M. Holland, Jörg Eder, Holger Sellner, Anna Schubart, Viviana P. Ferreira, Lee-Ann H. Allen, Ilse Jongerius, Taco W. Kuijpers, Sora Suzuki, Mieke C. Brouwer, Cathelijn E.M. Aarts, Ivy L. Debreceni, Stephanie L. Silva-Del Toro, Kaitlyn Howard, Jason Ricciuti, ANM Nazmul H. Khan, Kelly L. Singel, Thejaswini Giridharan, Tiffany R. Emmons
Supplementary Figure S3: OC ascites fluid activates the classical and alternative pathways.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e9d0756f962f510cedda4ba0a9a0f6
https://doi.org/10.1158/2326-6066.22543210.v1
https://doi.org/10.1158/2326-6066.22543210.v1
Autor:
Brahm H. Segal, Scott I. Abrams, Kunle Odunsi, Kirsten B. Moysich, Kevin H. Eng, Joseph D. Tario, Brandon E. Smith, Jaron Mark, Kelly L. Singel, Emad Alqassim, Jerry T. Wong, Tiffany R. Emmons, ANM Nazmul H. Khan
Anti-human mAb used in flow cytometry analysis and cell sorting for this study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa5196431f5505a1127d1005d5a5b12
https://doi.org/10.1158/2326-6066.22543876
https://doi.org/10.1158/2326-6066.22543876
Autor:
Brahm H. Segal, Scott I. Abrams, Kunle Odunsi, Kirsten B. Moysich, Kevin H. Eng, Joseph D. Tario, Brandon E. Smith, Jaron Mark, Kelly L. Singel, Emad Alqassim, Jerry T. Wong, Tiffany R. Emmons, ANM Nazmul H. Khan
CD33+CD11b+CD14-CD15- fraction of OC ascites cells contains variable proportions of HLA-DR+CD123mid dendritic cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034db8b27066c011ffd9acab3c2e2027
https://doi.org/10.1158/2326-6066.22543879
https://doi.org/10.1158/2326-6066.22543879
Autor:
Brahm H. Segal, Scott I. Abrams, Kunle Odunsi, Kirsten B. Moysich, Kevin H. Eng, Joseph D. Tario, Brandon E. Smith, Jaron Mark, Kelly L. Singel, Emad Alqassim, Jerry T. Wong, Tiffany R. Emmons, ANM Nazmul H. Khan
Myeloid derived suppressor cells (MDSC) are a heterogeneous group of immature cells that accumulate in the peripheral blood and tumor microenvironment and are barriers to cancer therapy. MDSCs serve as prognostic biomarkers and are targets for therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b9e356f13231f058217c5858429e71
https://doi.org/10.1158/2326-6066.c.6550441.v1
https://doi.org/10.1158/2326-6066.c.6550441.v1
Autor:
Brahm H. Segal, Emese Zsiros, Michael B. Yaffe, Kunle Odunsi, Kirsten B. Moysich, Kevin H. Eng, James A. Lederer, Sanjay Ram, Steven M. Holland, Jörg Eder, Holger Sellner, Anna Schubart, Viviana P. Ferreira, Lee-Ann H. Allen, Ilse Jongerius, Taco W. Kuijpers, Sora Suzuki, Mieke C. Brouwer, Cathelijn E.M. Aarts, Ivy L. Debreceni, Stephanie L. Silva-Del Toro, Kaitlyn Howard, Jason Ricciuti, ANM Nazmul H. Khan, Kelly L. Singel, Thejaswini Giridharan, Tiffany R. Emmons
T-cell activation and expansion in the tumor microenvironment (TME) are critical for antitumor immunity. Neutrophils in the TME acquire a complement-dependent T-cell suppressor phenotype that is characterized by inhibition of T-cell proliferation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d4f40cc451070fd401b4b199f38dd0
https://doi.org/10.1158/2326-6066.c.6550174
https://doi.org/10.1158/2326-6066.c.6550174
Autor:
Viviana P. Ferreira, Ilse Jongerius, Kelly L. Singel, Kunle Odunsi, Stephanie L. Silva-Del Toro, Thejaswini Giridharan, Anm Nazmul H. Khan, Jason Ricciuti, Kirsten B. Moysich, Kaitlyn Howard, Emese Zsiros, Kevin H. Eng, Tiffany R. Emmons, Brahm H. Segal, James A. Lederer, Sora Suzuki, Cathelijn E.M. Aarts, Holger Sellner, Taco W. Kuijpers, Mieke C. Brouwer, Steven M. Holland, Joerg Eder, Michael B. Yaffe, Ivy L. Debreceni, Anna Schubart, Sanjay Ram, Lee-Ann H. Allen
Publikováno v:
Cancer immunology research, 9(7), 790-810. American Association for Cancer Research Inc.
T-cell activation and expansion in the tumor microenvironment (TME) are critical for antitumor immunity. Neutrophils in the TME acquire a complement-dependent T-cell suppressor phenotype that is characterized by inhibition of T-cell proliferation and