Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tiffany M. Mott"'
Autor:
Tiffany M. Mott, R. Katie Johnston, Sudhamathi Vijayakumar, D. Mark Estes, Massoud Motamedi, Elena Sbrana, Janice J. Endsley, Alfredo G. Torres
Publikováno v:
Pathogens, Vol 2, Iss 2, Pp 383-401 (2013)
Burkholderia mallei, the etiologic agent of glanders, are Category B select agents with biothreat potential, and yet effective therapeutic treatments are lacking. In this study, we showed that CpG administration increased survival, demonstrating prot
Externí odkaz:
https://doaj.org/article/268097a2cbd14bc39e282a01b1e152bd
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175983 (2017)
Burkholderia pseudomallei (Bpm) is a saprophytic rod-shaped gram-negative bacterium and the causative agent of melioidosis. This disease has previously been described as endemic in areas such as northern Australia and Southeast Asia, but, more recent
Externí odkaz:
https://doaj.org/article/6d0f4964a14145c48e6cb976cc0e71e7
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 6, p e0003863 (2015)
BACKGROUND:In this study, a Burkholderia mallei tonB mutant (TMM001) deficient in iron acquisition was constructed, characterized, and evaluated for its protective properties in acute inhalational infection models of murine glanders and melioidosis.
Externí odkaz:
https://doaj.org/article/1316b74196ec448ba0e334715296578f
Autor:
Sathish Rajamani, Kurt E. Schaecher, Reuel A Sandy, Jennifer N Dootz, Evan M Falcinelli, Allen J. Duplantier, Rekha G. Panchal, Malathy Krishnamurthy, Margaret M. Lemmon, Tiffany M Mott
Publikováno v:
Infection and Drug Resistance. 12:1393-1405
Purpose: The rapid emergence of multidrug-resistant (MDR) bacteria and the lack of new therapies to eliminate them poses a major threat to global health. With the alarming rise in antimicrobial resistance (AMR), focus has now shifted to the use of th
Autor:
Shane eMassey, Katie eJohnston, Tiffany M Mott, Barbara M Judy, Brian H Kvitko, Herbert P Schweizer, D Mark Estes, Alfredo G Torres
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 2 (2011)
Bioluminescent imaging (BLI) technology is a powerful tool for monitoring infectious disease progression and treatment approaches. BLI is particularly useful for tracking fastidious intracellular pathogens that might be difficult to recover from cert
Externí odkaz:
https://doaj.org/article/56b305a3af0741acad502466fe1319fd
Publikováno v:
Current Tropical Medicine Reports. 4:199-207
Burkholderia pseudomallei and B. mallei are the etiological agents of severe diseases melioidosis and glanders, respectively, and are recalcitrant to many antibiotics. This review highlights recent findings on the quorum sensing (QS) systems of these
Autor:
Kamal U. Saikh, Tiffany M. Mott
Publikováno v:
Current Opinion in Infectious Diseases
Purpose of review Burkholderia mallei is a facultative intracellular pathogen that causes the highly contagious and often the fatal disease, glanders. With its high rate of infectivity via aerosol and recalcitrance toward antibiotics, this pathogen i
Publikováno v:
Infection and Immunity. 84:2345-2354
Burkholderia mallei is the causative agent of glanders, an incapacitating disease with high mortality rates in respiratory cases. Its endemicity and ineffective treatment options emphasize its public health threat and highlight the need for a vaccine
Autor:
Susan L. Welkos, Tiffany M. Mott, M. Hunter, J.L. Shoe, K.A. Fritts, Avery V. Quirk, Christopher K. Cote, A.M. Woodson, Christopher P. Klimko
Publikováno v:
Journal of applied microbiology. 122(5)
AIMS In an attempt to devise decontamination methods that are both effective and minimally detrimental to the environment, we evaluated germination induction as an enhancement to strategies for Bacillus anthracis spore decontamination. To determine a
Publikováno v:
Journal of Clinical Microbiology. 48:4186-4192
Patients with cystic fibrosis (CF) are susceptible to chronic respiratory infections with a number of bacterial pathogens. Among them, the Burkholderia cepacia complex (Bcc) bacteria, consisting of nine related species, have emerged as problematic CF