Výsledky vyhledávání - "Tiffany L. Wilson"

Enaminones: Exploring Additional Therapeutic Activities

Autor: Noha N. Salama, Natalie D. Eddington, Ivan O. Edafiogho, Kethireddy V.V. Ananthalakshmi, Samuel B. Kombian, Patrice L. Jackson, K. R. Scott, Mariano S. Alexander, Tiffany L. Wilson, Clive D. Hanson

Publikováno v: Journal of Pharmaceutical Sciences. 96:2509-2531

Enaminones, enamines of beta-dicarbonyl compounds, have been known for many years. Their early use has been relegated to serving as synthetic intermediates in organic synthesis and of late, in pharmaceutical development. Recently, the therapeutic pot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23838db88d4d3899c10282d6f25ffe1d
https://doi.org/10.1002/jps.20967

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Enaminones 9. Further studies on the anticonvulsant activity and potential type IV phosphodiesterase inhibitory activity of substituted vinylic benzamides

Autor: Ray J. Butcher, Alan J. Anderson, Jesse M. Nicholson, Tiffany L. Wilson, Kenneth R. Scott, Oladapo Bakare

Publikováno v: Bioorganic & Medicinal Chemistry. 14:997-1006

Structure-activity relationship studies were employed to synthesize a series of 3- and 3,4-substituted benzamides from 3-amino-2-cyclohexenones. An improved method for the synthesis of benzamides from 3-amino-2-cyclohexenones is presented which provi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec4b40204b1a76520ae06c54927a58b4
https://doi.org/10.1016/j.bmc.2005.09.023

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Conformational Analysis and Molecular Properties of N-(Substituted Phenylcarbonylamino)- 4-(1-Hydroxymethylphenyl)-1,2,3,6-Tetrahydropyridines

Autor: Kinfe K. Redda, Cosmas O. Okoro, Tiffany L. Wilson

Publikováno v: Current Medicinal Chemistry. 10:313-320

The three-dimensional structures of active derivatives of N-(substitutedphenylcarbonylamino)-4-(1-hydroxymethylphenyl)-1,2,3,6-tetrahydropyri-dines, which have previously been shown to possess anti-inflammatory activities, were built using BIOMEDCAch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a91cb5be074b54cff4b72cbed29f3de5
https://doi.org/10.2174/0929867033368303

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The Synthesis Of Several N-(Substituted Phenylcarbonylamino)-4-(3-cyclohexenyl)-1,2,3,6-tetrahydropyridines as Potential Anti-Inflam-Matory Agents

Autor: Udobi C. Onubogu, Kyoung-Jin Yoon, Cosmas O. Okoro, Kinfe K. Redda, Tiffany L. Wilson, Clanicia J. Pelle

Publikováno v: Synthetic Communications. 26:2703-2714

Several N-(substituted phenylcarbonylamino)-4-cyclohexenyl-1,2,3,6-tetrahydropyridines 7 were synthesized via sodium borohydride reduction of the corresponding N-(substituted phenylcarbonylimino)-4...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c75d87a7a526083449857a922541b2a
https://doi.org/10.1080/00397919608004587

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Multidrug resistance and anticonvulsants: new studies with some enaminones

Autor: Debra Payne, Tiffany L. Wilson, Noha N. Salama, Natalie D. Eddington, Kenneth R. Scott

Publikováno v: Current medicinal chemistry. 11(15)

The multidrug resistance (MDR), often conferred by the active extrusion of drugs from the cell, is a phenomenon often seen in cancer cells that may become resistant to a wide spectrum of drugs with varying chemical structures or cellular targets. Thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f1ca0213ea049f31c6b8c5eef9396a
https://pubmed.ncbi.nlm.nih.gov/15279569

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