Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Tiffany K. Roberts-Wilson"'
Publikováno v:
Journal of Renal Nutrition. 20:S24-S28
Muscle atrophy is a significant consequence of chronic kidney disease that increases a patient's risk of mortality and decreases their quality of life. The loss of lean body mass results, in part, from an increase in the rate of muscle protein degrad
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 423
Secondary amenorrhea in women of reproductive age may be an indication of an undiagnosed, chronic condition and appropriate treatment is dependent upon accurate diagnosis of the underlying etiology. A thorough clinical assessment and a few common lab
Publikováno v:
MLO: medical laboratory observer. 44(6)
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 24(8)
Muscle atrophy is a consequence of chronic diseases (e.g., diabetes) and glucocorticoid-induced insulin resistance that results from enhanced activity of the ubiquitin-proteasome pathway. The PI3K/Akt pathway inhibits the FOXO-mediated transcription
Publikováno v:
The FASEB Journal. 24
Calcineurin signaling and PGC-1alpha expression are suppressed during muscle atrophy due to diabetes
Autor:
Ramesh N. Reddy, Bin Zheng, James L. Bailey, S. Russ Price, Jennifer L. Gooch, Ronald J. Ordas, Tiffany K. Roberts-Wilson
Publikováno v:
Biochimica et biophysica acta. 1803(8)
PGC-1alpha is a transcriptional coactivator that controls energy homeostasis through regulation of glucose and oxidative metabolism. Both PGC-1alpha expression and oxidative capacity are decreased in skeletal muscle of patients and animals undergoing
Publikováno v:
Human Immunology. 74:168
Aim Single antigen beads (SABs) are becoming the preferred, and in some instances the sole, methodology to identify HLA antibodies. The aim of this study was to investigate cases in which SABs did not agree with the FlowPRA® screening assay. Methods
Autor:
Gizem Tumer, Robert A. Bray, Farris B. Alton, Tiffany K. Roberts-Wilson, Howard M. Gebel, Stuart N. Lauren
Publikováno v:
Human Immunology. 74:98
Aim To analyze the relationship between AMR, renal biopsy C4d staining and circulating DSA (MFI) levels. Methods Twenty four patients with confirmed DSAs and allograft biopsies were evaluated. HLA class I and II DSAs in sera collected at the time of
Publikováno v:
Human Immunology. 74:95
Aim Luminex®-based SAB testing is often used as a semi-quantitative assay to monitor HLA antibody levels pre- and post-transplant. However, the SAB assay is predominantly a manual and non-standardized method that exhibits a high degree of variabilit
Publikováno v:
Human Immunology. 74:80
Aim To investigate discrepancies between different solid phase HLA antibody detection platforms. Methods Sera from two patients implanted with a VAD were tested for Class I and II antibodies using FlowPRA screening beads, HLA phenotype beads (flow cy