Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tiffany Hurd"'
Autor:
Guangyi Wang, Marija Prhavc, Jennifer L. Brooks, Tiffany Hurd, P. Dan Cook, Vivek K. Rajwanshi, Patrick Fagan
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 24:179-189
3'-Azido-3',5-dideoxythymidine 5'-phosphonate and 3',5'-dideoxy-5'-difluoromethylenethymidine 5'-phosphonate were prepared by multistep syntheses. The nucleoside 5'-phosphonates were converted to their triphosphates and triphosphate mimics (P3Ms) con
Autor:
Nicholas A. Boyle, Vivek K. Rajwanshi, Fu Chen, P. Dan Cook, Jennifer L. Brooks, Marija Prhavc, Tiffany Hurd, Patrick Fagan, Guangyi Wang, Janet M. Leeds, Gregory Ewing, Thomas W. Bruice
Publikováno v:
Journal of medicinal chemistry. 48(7)
The triphosphates of antiviral 2',3'-dideoxynucleosides (ddNs) are the active chemical species that inhibit viral DNA synthesis. The inhibition involves incorporation of ddNMP into DNA and subsequent chain termination. A conceivable strategy for anti
Autor:
Patrick Fagan, Jennifer L. Brooks, Tiffany Hurd, Vasanthakumar Rajappan, Nicholas A. Boyle, P. Dan Cook, Marija Prhavc, Yi Jin, Thomas W. Bruice, Fu Chen, Vivek K. Rajwanshi, Janet M Leeds, Guangyi Wang
Publikováno v:
Journal of medicinal chemistry. 47(27)
In search of active nucleoside 5'-triphosphate mimics, we have synthesized a series of AZT triphosphate mimics (AZT P3Ms) and evaluated their inhibitory effects on HIV-1 reverse transcriptase as well as their stability in fetal calf serum and in CEM
Autor:
Patrick Fagan, Kandasamy Sakthivel, Tiffany Hurd, Janet M. Leeds, Vasanthakumar Rajappan, Kathleen D. Tucker, Jennifer L. Brooks, Guangyi Wang, P. Dan Cook, Thomas W. Bruice
Publikováno v:
Nucleosides, nucleotidesnucleic acids. 23(1-2)
IMPDH inhibitors have potential antimicrobial, anticancer and immunomodulatory effects. Nucleoside inhibitors of IMPDH exert their inhibitory effects via nucleoside 5′‐MPs. Conversion of nucleoside analogs to NMPs by cellular nucleoside kinases i
Autor:
Rajwanshi, VivekK.1 (AUTHOR), Prhavc, Marija1 (AUTHOR), Fagan, Patrick1 (AUTHOR), Brooks, JenniferL.1 (AUTHOR), Hurd, Tiffany1 (AUTHOR), Cook, P.Dan1 (AUTHOR), Wang, Guangyi1,2 (AUTHOR) g.wang@biota-inc.com
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. Mar2005, Vol. 24 Issue 3, p179-189. 11p. 3 Diagrams.
Autor:
Wang, Guangyi1 (AUTHOR) g.wang@biota-inc.com, Sakthivel, Kandasamy1 (AUTHOR), Rajappan, Vasanthakumar1 (AUTHOR), Bruice, ThomasW.1 (AUTHOR), Tucker, Kathleen1 (AUTHOR), Fagan, Patrick1 (AUTHOR), Brooks, JenniferL.1 (AUTHOR), Hurd, Tiffany1 (AUTHOR), Leeds, JanetM.1 (AUTHOR), Cook, P.Dan1 (AUTHOR)
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. Jan2004, Vol. 23 Issue 1/2, p317-337. 21p. 6 Diagrams, 1 Chart.
Publikováno v:
Wyoming Business Report. 2013 Manufacturers Directory, p13-88. 76p.
Autor:
Gilmore
Publikováno v:
Shooting Industry. Aug2013, Vol. 58 Issue 8, p34-34. 1/2p.
Autor:
Jamie Frater
A collection of crazy-but-true facts, peculiar occurrences, despicable crimes, bizarre records, unbelievable creatures, and many more shocking oddities.Delving into the shocking side of pop culture, science and history, Listverse.com's Epic Book of