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Autor:
Jan Grünewald, Qian Fan, David H. Jones, Ansgar Brock, Linda Okach, Scott A. Lesley, Tiffany Crossgrove, Lisa Quinn, Weijia Ou, Hsien-Po Chiu, Tetsuo Uno, Susan E. Cellitti, Bernhard H. Geierstanger, Paula Patterson, Xueshi Hao
Publikováno v:
Proceedings of the National Academy of Sciences. 108:10437-10442
Pyrroline-carboxy-lysine (Pcl) is a demethylated form of pyrrolysine that is generated by the pyrrolysine biosynthetic enzymes when the growth media is supplemented with D-ornithine . Pcl is readily incorporated by the unmodified pyrrolysyl-tRNA/tRNA