Výsledky vyhledávání - "Tiffany C. Y. Tan"

Investigation of refractive index dynamics during embryo development using digital holographic microscopy

Autor: George O. Dwapanyin, Darren J. X. Chow, Tiffany C. Y. Tan, Nicolas S. Dubost, Josephine M. Morizet, Kylie R. Dunning, Kishan Dholakia

Embryo quality is a crucial factor affecting live birth outcomes. However, an accurate diagnostic for embryo quality remains elusive in thein vitrofertilization clinic. Determining physical parameters of the embryo may offer key information for this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::499f760841c3456c7dc926dd8851b297
https://doi.org/10.1101/2023.04.17.537152

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Non-invasive, label-free optical analysis to detect aneuploidy within the inner cell mass of the preimplantation embryo

Autor: Jared M. Campbell, Carl A. Campugan, Ryan D Rose, Ewa M. Goldys, Abbas Habibalahi, Sanam Mustafa, Saabah B. Mahbub, Tiffany C. Y. Tan, Kylie R. Dunning, Darren J X Chow

Publikováno v: Human Reproduction. 37:14-29

STUDY QUESTION Can label-free, non-invasive optical imaging by hyperspectral autofluorescence microscopy discern between euploid and aneuploid cells within the inner cell mass (ICM) of the mouse preimplantation embryo? SUMMARY ANSWER Hyperspectral au

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7329c27451babc0214efa0a22e15c9ba
https://doi.org/10.1093/humrep/deab233

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Vitrification within a nanoliter volume: oocyte and embryo cryopreservation within a 3D photopolymerized device

Autor: Suliman H. Yagoub, Megan Lim, Tiffany C. Y. Tan, Darren J. X. Chow, Kishan Dholakia, Brant C. Gibson, Jeremy G. Thompson, Kylie R. Dunning

Publikováno v: Journal of Assisted Reproduction and Genetics.

Purpose Vitrification permits long-term banking of oocytes and embryos. It is a technically challenging procedure requiring direct handling and movement of cells between potentially cytotoxic cryoprotectant solutions. Variation in adherence to timing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f93b08523f909604db318869a333c18f
https://doi.org/10.1007/s10815-022-02589-8

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Optical imaging detects metabolic signatures associated with oocyte quality

Autor: Tiffany C Y Tan, Hannah M Brown, Jeremy G Thompson, Sanam Mustafa, Kylie R Dunning

Publikováno v: Biology of Reproduction.

Oocyte developmental potential is intimately linked to metabolism. Existing approaches to measure metabolism in the cumulus oocyte complex (COC) do not provide information on the separate cumulus and oocyte compartments. Development of an assay that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8cfbc4f064296768d5fb51e6ea2ac80
https://doi.org/10.1093/biolre/ioac145

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Optical imaging of cleavage stage bovine embryos using hyperspectral and confocal approaches reveals metabolic differences between on-time and fast-developing embryos

Autor: Ana Maria Reis Ferreira, Tiffany C. Y. Tan, Jeremy G. Thompson, Kylie R. Dunning, Clara Ana Santos Monteiro, Darren J X Chow, Gabriela Ramos Leal

Publikováno v: Theriogenology. 159:60-68

The assessment of embryo quality aims to enhance subsequent pregnancy and live birth outcomes. Metabolic analysis of embryos has immense potential in this regard. As a step towards this goal, here we assess the metabolism of bovine embryos using labe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ffb7d7fcdc9d399776228554868cddb
https://doi.org/10.1016/j.theriogenology.2020.10.012

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The effect of discrete wavelengths of visible light on the developing murine embryo

Autor: Carl A. Campugan, Megan Lim, Darren J. X. Chow, Tiffany C. Y. Tan, Tong Li, Avishkar A. Saini, Antony Orth, Philipp Reineck, Erik P. Schartner, Jeremy G. Thompson, Kishan Dholakia, Kylie R. Dunning

Publikováno v: Journal of assisted reproduction and genetics. 39(8)

Open Access funding enabled and organized by CAUL and its Member Institutions KRD is supported by a Mid-Career Fellowship from the Hospital Research Foundation (C-MCF-58–2019). KD is supported by funding from the UK Engineering and Physical Science

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff264be865b58dbae753d95dd9b2747
https://pubmed.ncbi.nlm.nih.gov/35737174

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Label-free multispectral identification of native fluorophores to assess embryo and oocyte quality

Autor: Michael J. Bertoldo, Dale M. Goss, Kylie R. Dunning, Ewa M. Goldys, Tiffany C. Y. Tan, Abbas Habibalahi, Kirsty Walter, Lindsay E. Wu, Saabah B. Mahbub, Jared M. Campbell

Publikováno v: Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XIX.

Our approach to multispectral fluorescence microscopy can non-invasively identify the biomolecular composition of cells and capture complex biological heterogeneity which is fundamentally important for biological research and medical diagnostics. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fdf60ec7133c3b1ca9f1094b89e1ff54
https://doi.org/10.1117/12.2579141

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