Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tiffany C. Taylor"'
Autor:
Felix E.Y. Aggor, Martinna Bertolini, Chunsheng Zhou, Tiffany C. Taylor, Darryl A. Abbott, Javonn Musgrove, Vincent M. Bruno, Timothy W. Hand, Sarah L. Gaffen
Publikováno v:
JCI Insight, Vol 7, Iss 18 (2022)
A side effect of antibiotics is outgrowth of the opportunistic fungus Candida albicans in the oropharynx (oropharyngeal candidiasis, OPC). IL-17 signaling is vital for immunity to OPC, but how the microbiome impacts antifungal immunity is not well un
Externí odkaz:
https://doaj.org/article/3e7129f8a12d4d8baf5f4651693398d2
Autor:
Tiffany C. Taylor, Yang Li, De-Dong Li, Saikat Majumder, Mandy J. McGeachy, Partha S. Biswas, Sebastien Gingras, Sarah L. Gaffen
IL-17 contributes to the pathogenesis of certain autoimmune diseases, but conversely is essential for host defense against fungi. Antibody-based biologic drugs that neutralize IL-17 are effective in autoimmunity but can be accompanied by adverse side
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1c114166101b1cffa1589a194a494f
https://doi.org/10.1101/2022.02.14.480386
https://doi.org/10.1101/2022.02.14.480386
Autor:
Nandan S. Gokhale, Sarah L. Gaffen, Rami Bechara, Nilesh Amatya, Stacy M. Horner, Yang Li, Rachel D. Bailey, Bianca M. Coleman, Partha S. Biswas, Felix E. Y. Aggor, Chetan V. Jawale, Ning Dai, Anita Bansal, Tiffany C. Taylor, Amanda C. Poholek, De-Dong Li
Publikováno v:
Science Immunology. 6
Excessive cytokine activity underlies many autoimmune conditions, particularly through the interleukin-17 (IL-17) and tumor necrosis factor-α (TNFα) signaling axis. Both cytokines activate nuclear factor κB, but appropriate induction of downstream
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19e442551eb979d8552cfac874280490
https://doi.org/10.1126/sciimmunol.abd1287
https://doi.org/10.1126/sciimmunol.abd1287
Autor:
Rami, Bechara, Nilesh, Amatya, Rachel D, Bailey, Yang, Li, Felix E Y, Aggor, De-Dong, Li, Chetan V, Jawale, Bianca M, Coleman, Ning, Dai, Nandan S, Gokhale, Tiffany C, Taylor, Stacy M, Horner, Amanda C, Poholek, Anita, Bansal, Partha S, Biswas, Sarah L, Gaffen
Publikováno v:
Sci Immunol
Excessive cytokine activity underlies many autoimmune conditions, particularly through the IL-17 and TNFα signaling axes. Both cytokines activate NF-κB, but appropriate induction of downstream effector genes requires coordinated activation of other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::97866a26698a56b15207a65324e939d8
https://pubmed.ncbi.nlm.nih.gov/34215679
https://pubmed.ncbi.nlm.nih.gov/34215679
Autor:
Rami Bechara, Nilesh Amatya, Rachel D. Bailey, Yang Li, Felix EY Aggor, De-Dong Li, Chetan V. Jawale, Bianca M. Coleman, Ning Dai, Nandan S. Gokhale, Tiffany C. Taylor, Stacy M. Horner, Amanda C. Poholek, Partha S. Biswas, Sarah L. Gaffen
Publikováno v:
The Journal of Immunology. 206:22.06-22.06
Dysregulated activity of IL-17 underlies many autoimmune conditions, but the molecular mechanisms by which IL-17 mediates pathogenic inflammation remain poorly understood. IL-17 regulates pathogenic inflammatory genes by two key transcription factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c09da5d17c638187a91e7f6ea32c93e5
https://doi.org/10.4049/jimmunol.206.supp.22.06
https://doi.org/10.4049/jimmunol.206.supp.22.06
Autor:
Felix E Y Aggor, Martinna Bertolini, Bianca M Coleman, Tiffany C Taylor, Nicole O Ponde, Sarah L Gaffen
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012302 (2024)
Oropharyngeal candidiasis (OPC) is the most common human fungal infection, arising typically from T cell immune impairments. IL-17 and IL-22 contribute individually to OPC responses, but here we demonstrate that the combined actions of both cytokines
Externí odkaz:
https://doaj.org/article/00057ee8a517475cb226bbae4236d470