Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tiffany A. Wilke"'
Autor:
Todd A. Alonzo, Robert B. Gerbing, Stella M. Davies, Parinda A. Mehta, John P. Perentesis, Beverly J. Lange, Julie A. Ross, James Elliott, R.J. Kennedy, Tiffany A. Wilke
Publikováno v:
Blood. 107(1)
Genetic polymorphisms result in interindividual variation in DNA repair capacity and may, in part, account for susceptibility of a cell to genotoxic agents and to malignancy. Polymorphisms in XPD, a member of the nucleotide excision repair pathway, h
Autor:
Stella M. Davies, Susan Lee, Joyce Villanueva, Yetnayet Zewge, Ashok Kumar, Tiffany A. Wilke, Jeanette Pullen, Parinda A. Mehta, Alexandra H. Filipovich, Meenakshi Devidas, James Elliott
Publikováno v:
Blood. 106:1453-1453
Perforin plays a key role in the cytotoxicity of NK cells and cytotoxic T lymphocytes. Genetic mutations in perforin gene (PRF1) give rise to 30–40% of cases of familial hemophagocytic lymphohistiocytosis. We recently studied two boys who had been
Autor:
Stella M. Davies, Parinda A. Mehta, James Elliott, Daniel J. Weisdorf, Effie W. Petersdorf, Michelle D. Combs, Tiffany A. Wilke, Richard Aplenc, Mary Eapen, Sharavi Gandham, John P. Klein, Margaret L. MacMillan
Publikováno v:
Blood. 106:2057-2057
IL-1α is a pro-inflammatory cytokine implicated in initiation and maintenance of graft versus host disease (GVHD) and the immune response to infection. A cytosine (C) to thymine (T) transition at codon -889 is believed to influence gene transcriptio
Autor:
Todd A. Alonzo, James S. Elliot, John P. Perentesis, Stella M. Davies, Robert B. Gerbing, Tiffany A. Wilke, Parinda A. Mehta, Beverly J. Lange
Publikováno v:
Blood. 104:3011-3011
FAS (TNFRSF6/CD95/APO-1) is a cell surface receptor involved in apoptotic signal transmission. Dysregulation of this pathway is believed to result in down regulation of apoptosis and subsequent persistence of a malignant clone. A single nucleotide po