CRISPR based editing of SIV proviral DNA in ART treated non-human primates

Autor: Pietro Mancuso, Chen Chen, Rafal Kaminski, Jennifer Gordon, Shuren Liao, Jake A. Robinson, Mandy D. Smith, Hong Liu, Ilker K. Sariyer, Rahsan Sariyer, Tiffany A. Peterson, Martina Donadoni, Jaclyn B. Williams, Summer Siddiqui, Bruce A. Bunnell, Binhua Ling, Andrew G. MacLean, Tricia H. Burdo, Kamel Khalili

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)

Removal of integrated HIV DNA remains a roadblock for HIV cure. Here, Mancuso et al. show that intravenous administration of an adeno-associated virus-based CRISPR/Cas9 gene editing construct to SIV-infected macaques results in excision of integrated

Externí odkaz: https://doaj.org/article/8cbe71bbcb2e47d19d5219446802dbe4

Immediate effect of the COVID-19 pandemic on patient health, health-care use, and behaviours: results from an international survey of people with rheumatic diseases

Autor: Jonathan S Hausmann, Kevin Kennedy, Julia F Simard, Jean W Liew, Jeffrey A Sparks, Tarin T Moni, Carly Harrison, Maggie J Larché, Mitchell Levine, Sebastian E Sattui, Teresa Semalulu, Gary Foster, Salman Surangiwala, Lehana Thabane, Richard P Beesley, Karen L Durrant, Elsa F Mateus, Serena Mingolla, Michal Nudel, Candace A Palmerlee, Dawn P Richards, David F L Liew, Catherine L Hill, Suleman Bhana, Wendy Costello, Rebecca Grainger, Pedro M Machado, Philip C Robinson, Paul Sufka, Zachary S Wallace, Jinoos Yazdany, Emily Sirotich, Philip C. Robinson, Jean W. Liew, Paul H. Sufka, Namrata Singh, Richard A. Howard, Alfred H.J. Kim, Tiffany Westrich-Robertson, Edmund Tsui, Ali Duarte-Garcia, Jeffrey A. Sparks, Herman Tam, Arundathi Jayatilleke, Maximilian F. Konig, Elizabeth R. Graef, Michael S. Putman, Reema H. Syed, Peter Korsten, Elsa Mateus, Sebastian E. Sattui, Zachary S. Wallace, Upton A. Laura, Kilian Adam, Yu Pei Eugenia Chock, Douglas W. White, Geraldine T. Zamora, Lisa S. Traboco, Aarat M. Patel, Manuel F. Ugarte-Gil, Milena A. Gianfrancesco, Isabelle Amigues, Catalina Sanchez-Alvarez, Laura Trupin, Lindsay R. Jacobsohn, Richard P. Beesley, Bimba F. Hoyer, Pedro M. Machado, Kavita Makan, Laure Gossec, Chaudhary Priyank, Jan Leipe, Beth Wallace, Sheila T. Angeles-Han, Ibrahim A. Almaghlouth, Wysham D. Katherine, Anthony S. Padula, Francis Berenbaum, Erin M. Treemarcki, Rashmi Sinha, Laura B. Lewandowski, Kate Webb, Kristen J. Young, Inita Bulina, Sebastian Herrera Uribe, Tamar B. Rubinstein, Marc W. Nolan, Elizabeth Y. Ang, Swamy R. Venuturupalli, Jonathan S. Hausmann, Maureen Dubreuil, Cecilia N. Pisoni, Micaela A. Cosatti, Jose Campos, Julia F. Simard, Richard Conway, Tiffany M. Peterson, Carly O. Harrison, Christele Felix, Dawn P. Richards, Laurie Proulx, Akpabio A. Akpabio, Angus B. Worthing, Lynn R. Laidlaw, Pankti Reid, Candace A. Palmerlee, Maria I. Danila, Lotfi-Emran Sahar, Ngo Q. Linh, Arnav Agarwal, Paul Studenic, David F.L. Liew, Maggie J. Larche, Serena A.M. Mingolla, Erick A. Zamora, Saskya S. Angevare, Rashmi R. Sinha, Karen L.W. Durrant, Andrea Peirce, Emily C. Somers, Laura C. Cappelli, Brittany A. Frankel, Bharat Kumar, Sonia D. Silinsky Krupnikova, Jorge A. Rosario Vega, Jourdan Frankovich, Ruth Fernandez-Ruiz, Marcela Posada Velásquez, Su-Ann Yeoh, Maria Marino, Chrisiaan Scott, Cecilia Rodríguez, Ana I. Martín Mancheño, Philip Seo, Rocío V. Gamboa-Cárdenas, Victor R. Pimentel-Quiroz, Cristina Reátegui-Sokolova, Mari Kihara, Chung M.A. Lin, Dheera Kattula, Girgis Laila, Loreto Carmona, John Wallace, Monique C. Gore-massy, Laura-Ann Tomasella, Moré A. Kodek

Publikováno v: The Lancet. Rheumatology

Background: The impact and consequences of the COVID-19 pandemic on people with rheumatic disease are unclear. We developed the COVID-19 Global Rheumatology Alliance Patient Experience Survey to assess the effects of the COVID-19 pandemic on people w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::448fed1950a8b73e8aa3446bf6c5eeb4
http://europepmc.org/articles/PMC8298011

Contributors

Autor: Angela Marie Abbatecola, Ahmed Abdellatif, Shameemah Abrahams, Anne Almey, Sevilhan Artan, Hamdino Attia, Karina Ausin, Soraya Bardien, Martin Bareš, Minke Bekker, Amogh Belagodu, Antonello Bellomo, Olga A. Belova, Sebastián Beltrán-Castillo, Agata Białecka-De¸bek, Karina Henrique Binda, Daniel M. Blumberger, Mariangela Boccardi, Virginia Boccardi, Benjamin D. Boros, Luca Anna Bors, Alessandro Bortolami, Daniel C. Bowie, Francesca Bruno, Paulo Caramelli, G.P. Cardona-Gómez, Jonathan Carr, Paz Cartas-Cejudo, Gemma Casadesus, Grace M. Clements, Katelyn Cuttler, Antonio Daniele, Zafiris J. Daskalakis, Vittorio Dibello, Michelino Di Rosa, Velia D’Agata, Agata Grazia D’Amico, Andre du Toit, Mehrangiz Ebrahimi-Mameghani, B.J.L. Eggen, Okobi Ekpo, Franciska Erdő, Kirk I. Erickson, Ebru Erzurumluoglu Gokalp, Kurt A. Escobar, Jaime Eugenín, Monica Fabiani, Mahitab Farghali, Concetta Federico, Joaquín Fernández-Irigoyen, Federica Ferrari, Isidro Ferrer, Pavel Filip, Vanêssa Gomes Fraga, Mitsuhiro Furuse, Roberto Galvez, Samantha L. Gardener, Nicole J. Gervais, Gianluigi Giannelli, Laura Gil, Karina Braga Gomes, Andrea González-Morales, Stuart L. Graham, Gabriele Gratton, Antonio Greco, Andrey Grigoriev, Yian Gu, Lingyu Guan, Joshua M. Gulley, Vivek K. Gupta, Jeremy H. Herskowitz, Shozo Jinno, Lars Stiernman Jonasson, Mariona Jové, Shuo Kang, Michy P. Kelly, Ryuta Kinno, Maria G. Knyazeva, Joanne Koh, Marisa Koini, Yulia K. Komleva, Mercedes Lachén-Montes, Maddalena La Montagna, Anne Marlene Landau, Fulvio Lauretani, Ran Li, Yuandong Li, Xuan Li, Jennifer I. Lissemore, Ben Loos, Olga L. Lopatina, Madia Lozupone, Andrew G. MacLean, Tando Maduna, Marcello Maggio, Alireza Majdi, Hanani Abdul Manan, Raffaele Marfella, Grazia Maugeri, Naroa Mendizuri, Megan Mey, Kiyohito Mizutani, Claudio Molinari, Vera Morsanuto, Natalia Mota-Martorell, Sheeja Navakkode, Gina Nicoll, Kenjiro Ono, Demet Ozbabalik Adapinar, Reinald Pamplona, Francesco Panza, Tiffany A. Peterson, Irene Pradas, Victor R. Preedy, Stephanie R. Rainey-Smith, Caroline Cristiano Real, Catarina Rendeiro, Justin S. Rhodes, Georgia A.F. Rogerson, Sara Ruga, Salvatore Saccone, Saeed Sadigh-Eteghad, Vladimir V. Salmin, Alla B. Salmina, Mahzad Sanayei, Cristina Sanfilippo, Enrique Santamaría, Rodolfo Sardone, Heide Schatten, Davide Seripa, Federico Sesti, Ting Shen, Vincenzo Solfrizzi, Tuck Wah Soong, Anna Starnawska, Nicklas Heine Staunstrup, Chelsea Stillman, Valentina Sturiale, Yoshimi Takai, Dennis A. Turner, Francesca Uberti, Elnaz Vaghef-Mehrabany, Leila Vaghef-Mehrabany, Trisha A. VanDusseldorp, Roberto Federico Villa, J. Villamil-Ortiz, Rommy von Bernhardi, Ruikang K. Wang, Lauren Wengle, Yu-Chien Wu, Noorazrul Azmie Yahya, Jun Yamada, Wei Yang, Yuyi You, Ahmad Nazlim Yusoff, Jing Zhai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1708180369e2d2c0a4f369e659f8ea54
https://doi.org/10.1016/b978-0-12-817990-1.01002-7

CRISPR based editing of SIV proviral DNA in ART treated non-human primates

Autor: Kamel Khalili, Mandy D. Smith, Rahsan Sariyer, Pietro Mancuso, Jennifer Gordon, Bruce A. Bunnell, Hong Liu, Rafal Kaminski, Tricia H. Burdo, Ilker Kudret Sariyer, Jake A. Robinson, Tiffany A. Peterson, Andrew G. MacLean, Martina Donadoni, Binhua Ling, Summer Siddiqui, Shuren Liao, Chen Chen, Jaclyn B. Williams

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications

Elimination of HIV DNA from infected individuals remains a challenge in medicine. Here, we demonstrate that intravenous inoculation of SIV-infected macaques, a well-accepted non-human primate model of HIV infection, with adeno-associated virus 9 (AAV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff0bd71330bda63430b939d74e604d9
https://doi.org/10.1038/s41467-020-19821-7

Adverse event following live attenuated chikungunya vaccine in a cynomolgus macaque with pre‐existing chronic hydrocephalus

Autor: Tiffany A. Peterson, Scott C. Weaver, Kasi E. Russell-Lodrigue, Peter J. Didier, Chad J. Roy, Andrew G. MacLean

Publikováno v: Journal of Medical Primatology. 48:257-259

A cynomolgus macaque (Macaca fascicularis) with a pre-existing, undiagnosed, subclinical but severe cerebral hydrocephalus was enrolled in a study of long-term immunogenicity of the IRES/CHIK vaccine. The animal began showing signs of neurological dy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab366045b835ca65bdb965b38c3bab6d
https://doi.org/10.1111/jmp.12414