Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tiffany A. McLamarrah"'
Autor:
Brian J. Galletta, Carey J. Fagerstrom, Todd A. Schoborg, Tiffany A. McLamarrah, John M. Ryniawec, Daniel W. Buster, Kevin C. Slep, Gregory C. Rogers, Nasser M. Rusan
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
The centrosome is a large intracellular structure that serves as the microtubule-organising center, but how it is accurately assembled is not known. Here the authors generate a ‘domain-level’ centrosome interactome and show that Plk4 positions th
Externí odkaz:
https://doaj.org/article/bd602ba043d3456eb55d85545a7af134
Autor:
Gregory C. Rogers, Tiffany A. McLamarrah, Cody J. Boese, Kevin C. Slep, Nasser M. Rusan, Jonathan Nye, Daniel W. Buster, Amy E. Byrnes
Publikováno v:
Molecular Biology of the Cell
Centriole assembly initiates when Polo-like kinase 4 (Plk4) interacts with a centriole “targeting-factor.” In Drosophila, Asterless/Asl (Cep152 in humans) fulfills the targeting role. Interestingly, Asl also regulates Plk4 levels. The N-terminus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beafa3eb046e6042f5b9b6ee22879a2a
https://doi.org/10.1091/mbc.e18-07-0445
https://doi.org/10.1091/mbc.e18-07-0445
Autor:
Benjamin J. Nichols, Gregory C. Rogers, Steven H Caplan, Kriti Bahl, Trey Farmer, Shuwei Xie, Ivana Yeow, Naava Naslavsky, Tiffany A. McLamarrah, James B. Reinecke
Publikováno v:
Molecular Biology of the Cell
Centrosomes are the major microtubule-nucleating and microtubule-organizing centers of cells and play crucial roles in microtubule anchoring, organelle positioning, and ciliogenesis. At the centrosome core lies a tightly associated or “engaged” m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d71a6d9bcf254591adaf8674fc3c11cb
https://doi.org/10.1091/mbc.e18-04-0241
https://doi.org/10.1091/mbc.e18-04-0241
Autor:
Nasser M. Rusan, Gregory C. Rogers, Tiffany A. McLamarrah, Daniel W. Buster, Sarah K. Speed, Carey J. Fagerstrom, Brian J. Galletta
Centriole duplication begins with the assembly of a pre-procentriole at a single site on a mother centriole and proceeds with the hierarchical recruitment of a conserved set of proteins, including Polo-like kinase 4 (Plk4)/ZYG-1, Ana2/SAS-5/STIL, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9864e36ceb68752f1ad3c4b7503f597d
Autor:
Daniel W. Buster, Cody J. Boese, Natalie A. Hollingsworth, Kevin C. Slep, John M. Ryniawec, Amy E. Byrnes, Gregory C. Rogers, Christopher W. Brownlee, Brian J. Galletta, Tiffany A. McLamarrah, Nasser M. Rusan
Publikováno v:
The Journal of Cell Biology
Centriole duplication is tightly regulated throughout the cell cycle to ensure one duplication event per centriole. McLamarrah et al. show that a stepwise pattern of Ana2 phosphorylation by Plk4 facilitates proper centriole duplication.
Polo-lik
Polo-lik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97db2e34e63568e08259d73af6a42f6
Autor:
John M. Ryniawec, Daniel W. Buster, Tiffany A. McLamarrah, Gregory C. Rogers, Nasser M. Rusan, Carey J. Fagerstrom, Kevin C. Slep, Brian J. Galletta, Todd A. Schoborg
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
The centrosome is the major microtubule-organizing centre of many cells, best known for its role in mitotic spindle organization. How the proteins of the centrosome are accurately assembled to carry out its many functions remains poorly understood. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718aba7b3b770768603cf8ff2bfa6c0b
https://doi.org/10.1038/ncomms12476
https://doi.org/10.1038/ncomms12476
Autor:
Nasser M. Rusan, Tiffany A. McLamarrah, Joseph E. Klebba, Gregory C. Rogers, Daniel W. Buster
Publikováno v:
Proceedings of the National Academy of Sciences. 112
Polo-like kinase 4 (Plk4) is a master regulator of centriole duplication, and its hyperactivity induces centriole amplification. Homodimeric Plk4 has been shown to be ubiquitinated as a result of autophosphorylation, thus promoting its own degradatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc3441807d908f0ddb785df0d359b25
https://doi.org/10.1073/pnas.1417967112
https://doi.org/10.1073/pnas.1417967112