Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Tiffany A Heanue"'
Autor:
Sarah McCallum, Yuuki Obata, Evangelia Fourli, Stefan Boeing, Christopher J Peddie, Qiling Xu, Stuart Horswell, Robert N Kelsh, Lucy Collinson, David Wilkinson, Carmen Pin, Vassilis Pachnis, Tiffany A Heanue
Publikováno v:
eLife, Vol 9 (2020)
The presence and identity of neural progenitors in the enteric nervous system (ENS) of vertebrates is a matter of intense debate. Here, we demonstrate that the non-neuronal ENS cell compartment of teleosts shares molecular and morphological character
Externí odkaz:
https://doaj.org/article/2e57d2f002cf475ba4153d7c9abee0b6
Autor:
Tiffany A Heanue, Werend Boesmans, Donald M Bell, Koichi Kawakami, Pieter Vanden Berghe, Vassilis Pachnis
Publikováno v:
PLoS Genetics, Vol 12, Iss 11, p e1006439 (2016)
Hirschsprung disease (HSCR) is characterized by absence of enteric neurons from the distal colon and severe intestinal dysmotility. To understand the pathophysiology and genetics of HSCR we developed a unique zebrafish model that allows combined gene
Externí odkaz:
https://doaj.org/article/1fb37f9316e949369f6a56a009dfa865
Autor:
Yuuki Obata, Álvaro Castaño, Todd L. Fallesen, Ana Carina Bon-Frauches, Stefan Boeing, Almaz Huseynova, Sarah McCallum, Reena Lasrado, Tiffany A. Heanue, Vassilis Pachnis
Publikováno v:
Nature protocols. 17(8)
The enteric nervous system (ENS) is an extensive network of enteric neurons and glial cells that is intrinsic to the gut wall and regulates almost all aspects of intestinal physiology. While considerable advancement has been made in understanding the
Autor:
David G. Wilkinson, Christopher J. Peddie, Sarah McCallum, Stefan Boeing, Vassilis Pachnis, Yuuki Obata, Lucy M. Collinson, Stuart Horswell, Qiling Xu, Carmen Pin, Robert N. Kelsh, Tiffany A. Heanue, Evangelia Fourli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25cee60eab45b99b742df3c2203d2d2c
https://doi.org/10.7554/elife.56086.sa2
https://doi.org/10.7554/elife.56086.sa2
Autor:
Robert N. Kelsh, Yuuki Obata, Stuart Horswell, Lucy M. Collinson, Qiling Xu, Stefan Boeing, Tiffany A. Heanue, Vassilis Pachnis, Evangelia Fourli, Sarah McCallum, David G. Wilkinson, Christopher J. Peddie, Carmen Pin
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
The presence and identity of neural progenitors in the enteric nervous system (ENS) of vertebrates is a matter of intense debate. Here we demonstrate that the non-neuronal ENS cell compartment of teleosts shares molecular and morphological characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efe39c9a6c356655bb9b274fa1503c4b
Autor:
Alan J. Burns, Tiffany A. Heanue
Publikováno v:
Pediatric Neurogastroenterology ISBN: 9783319432663
Pediatric Neurogastroenterology ISBN: 9781607617082
Pediatric Neurogastroenterology ISBN: 9781607617082
In order for the gut to perform essential functions, including moving contents along its length via the organized movement of peristalsis, as well as absorption of water and electrolytes, secretion from glands, and regulation of blood flow, the integ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62313bf2a2d9cf32dc4dc29e7a264f2
https://doi.org/10.1007/978-3-319-43268-7_2
https://doi.org/10.1007/978-3-319-43268-7_2
Autor:
Tiffany A. Heanue, Vassilis Pachnis
Publikováno v:
Stem Cells (Dayton, Ohio)
The capacity to identify and isolate lineage-specific progenitor cells from developing and mature tissues would enable the development of cell replacement therapies for disease treatment. The enteric nervous system (ENS) regulates important gut funct
Autor:
Tiffany A. Heanue, Vassilis Pachnis
Publikováno v:
Mechanisms of Development. 125(8):687-699
The enteric nervous system (ENS) derives from migratory neural crest cells that colonize the developing gut tube, giving rise to an integrated network of neurons and glial cells, which together regulate important aspects of gut function, including co
Autor:
Raquel M. Fernández, Seneca L. Bessling, Grzegorz M. Burzynski, Albee Y. Ling, Salud Borrego, Isabella Ceccherini, Andrew S. McCallion, Aravinda Chakravarti, Moltu Guy, Robert M.W. Hofstra, Qian Jiang, Stacey Arnold, Jeffrey J. Gray, Jeanne Amiel, Krishna Praneeth Kilambi, Maria X. Sosa, Vassilis Pachnis, Betty Q. Doan, Ashish Kapoor, Stanislas Lyonnet, Qingguang Jiang, Tiffany A. Heanue, Kristen West, Joke B. G. M. Verheij, Paola Griseri
Publikováno v:
American Journal of Human Genetics, 96(4), 581-596. Cell Press
American Journal of Human Genetics, 96(4), 581-596. CELL PRESS
American Journal of Human Genetics, 96(4), 581-596. CELL PRESS
Innervation of the gut is segmentally lost in Hirschsprung disease (HSCR), a consequence of cell-autonomous and non-autonomous defects in enteric neuronal cell differentiation, proliferation, migration, or survival. Rare, high-penetrance coding varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd2d4cf6a8b58b92cd0ab303717bf29
https://pure.eur.nl/en/publications/c46aadce-e454-4bda-9baf-da43fde81518
https://pure.eur.nl/en/publications/c46aadce-e454-4bda-9baf-da43fde81518
Autor:
Graeme Mardon, Sumihare Noji, Yohei Shinmyo, Taro Mito, Katsuyuki Miyawaki, Kyoko Matsushima, Tiffany A. Heanue, Hideyo Ohuchi, Yoshiko Inoue
Publikováno v:
Mechanisms of Development. 113:141-148
We describe the expression pattern of Gryllus homothorax (Gbhth) and dachshund (Gbdac), a cricket homologue of Drosophila homothorax and dachshund, together with localization of Distal-less or Extradenticle protein during leg development. We correlat