Identification of pharmacological inducers of a reversible hypometabolic state for whole organ preservation

Autor: Megan M Sperry, Berenice Charrez, Haleh Fotowat, Erica Gardner, Kanoelani Pilobello, Zohreh Izadifar, Tiffany Lin, Abigail Kuelker, Sahith Kaki, Michael Lewandowski, Shanda Lightbown, Ramses Martinez, Susan Marquez, Joel Moore, Maria Plaza-Oliver, Adama M Sesay, Kostyantyn Shcherbina, Katherine Sheehan, Takako Takeda, Daniela Del Campo, Kristina Andrijauskaite, Exal Cisneros, Riley Lopez, Isabella Cano, Zachary Maxwell, Israel Jessop, Rafa Veraza, Leon Bunegin, Thomas J Percival, Jaclyn Yracheta, Jorge J Pena, Diandra M Wood, Zachary T Homas, Cody J Hinshaw, Jennifer Cox-Hinshaw, Olivia G Parry, Justin J Sleeter, Erik K Weitzel, Michael Levin, Michael Super, Richard Novak, Donald E Ingber

Publikováno v: eLife, Vol 13 (2024)

Drugs that induce reversible slowing of metabolic and physiological processes would have great value for organ preservation, especially for organs with high susceptibility to hypoxia-reperfusion injury, such as the heart. Using whole-organism screeni

Externí odkaz: https://doaj.org/article/095738c148254bf3aca1f94a4c99d2bb

Lung nodule malignancy classification with associated pulmonary fibrosis using 3D attention-gated convolutional network with CT scans

Autor: Yucheng Liu, Hao Yun Hsu, Tiffany Lin, Boyu Peng, Anjali Saqi, Mary M. Salvatore, Sachin Jambawalikar

Publikováno v: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-12 (2024)

Abstract Background Chest Computed tomography (CT) scans detect lung nodules and assess pulmonary fibrosis. While pulmonary fibrosis indicates increased lung cancer risk, current clinical practice characterizes nodule risk of malignancy based on nodu

Externí odkaz: https://doaj.org/article/39ff6bbfb97640db82ad596582b1f6c6

Influenza associated pulmonary aspergillosis in california: A case series

Autor: John Z. Deng, Karlyn D. Beer, Mitsuru Toda, Brendan Jackson, Tiffany Lin, Marjan Javanbakht, Chrysovalantis Stafylis, Tom Chiller, Jeffrey D. Klausner

Publikováno v: Clinical Infection in Practice, Vol 13, Iss , Pp 100123- (2022)

Introduction: Invasive pulmonary aspergillosis has been reported to occur in patients who are critically ill with severe influenza. The mortality rate is high. Methods: We reviewed electronic medical records from University of California at Los Angel

Externí odkaz: https://doaj.org/article/76224d8a36b64d29a4694c3f44b27a61

Expression-Based Cell Lineage Analysis in Drosophila Through a Course-Based Research Experience for Early Undergraduates

Autor: John M. Olson, Cory J. Evans, Kathy T. Ngo, Hee Jong Kim, Joseph Duy Nguyen, Kayla G. H. Gurley, Truc Ta, Vijay Patel, Lisa Han, Khoa T. Truong-N, Letty Liang, Maggie K. Chu, Hiu Lam, Hannah G. Ahn, Abhik Kumar Banerjee, In Young Choi, Ross G. Kelley, Naseem Moridzadeh, Awais M. Khan, Omair Khan, Szuyao Lee, Elizabeth B. Johnson, Annie Tigranyan, Jay Wang, Anand D. Gandhi, Manish M. Padhiar, Joseph Hargan Calvopina, Kirandeep Sumra, Kristy Ou, Jessie C. Wu, Joseph N. Dickan, Sabrena M. Ahmadi, Donald N. Allen, Van Thanh Mai, Saif Ansari, George Yeh, Earl Yoon, Kimberly Gon, John Y. Yu, Johnny He, Jesse M. Zaretsky, Noemi E. Lee, Edward Kuoy, Alexander N. Patananan, Daniel Sitz, PhuongThao Tran, Minh-Tu Do, Samira J. Akhave, Silverio D. Alvarez, Bobby Asem, Neda Asem, Nicole A. Azarian, Arezou Babaesfahani, Ahmad Bahrami, Manjeet Bhamra, Ragini Bhargava, Rakesh Bhatia, Subir Bhatia, Nicholas Bumacod, Jonathan J. Caine, Thomas A. Caldwell, Nicole A. Calica, Elise M. Calonico, Carman Chan, Helen H.-L. Chan, Albert Chang, Chiaen Chang, Daniel Chang, Jennifer S. Chang, Nauman Charania, Jasmine Y. Chen, Kevin Chen, Lu Chen, Yuyu Chen, Derek J. Cheung, Jesse J. Cheung, Jessica J. Chew, Nicole B. Chew, Cheng-An Tony Chien, Alana M. Chin, Chee Jia Chin, Youngho Cho, Man Ting Chou, Ke-Huan K. Chow, Carolyn Chu, Derrick M. Chu, Virginia Chu, Katherine Chuang, Arunit Singh Chugh, Mark R. Cubberly, Michael Guillermo Daniel, Sangita Datta, Raj Dhaliwal, Jenny Dinh, Dhaval Dixit, Emmylou Dowling, Melinda Feng, Christopher M. From, Daisuke Furukawa, Himaja Gaddipati, Lilit Gevorgyan, Zunera Ghaznavi, Tulika Ghosh, Jaskaran Gill, David J. Groves, Kalkidan K. Gurara, Ali R. Haghighi, Alexandra L. Havard, Nasser Heyrani, Tanya Hioe, Kirim Hong, Justin J. Houman, Molly Howland, Elaine L. Hsia, Justin Hsueh, Stacy Hu, Andrew J. Huang, Jasmine C. Huynh, Jenny Huynh, Chris Iwuchukwu, Michael J. Jang, An An Jiang, Simran Kahlon, Pei-Yun Kao, Manpreet Kaur, Matthew G. Keehn, Elizabeth J. Kim, Hannah Kim, Michelle J. Kim, Shawn J. Kim, Aleksandar Kitich, Ross A. Kornberg, Nicholas G. Kouzelos, Jane Kuon, Bryan Lau, Roger K. Lau, Rona Law, Huy D. Le, Rachael Le, Carrou Lee, Christina Lee, Grace E. Lee, Kenny Lee, Michelle J. Lee, Regina V. Lee, Sean H. K. Lee, Sung Kyu Lee, Sung-Ling D. Lee, Yong Jun Lee, Megan J. Leong, David M. Li, Hao Li, Xingfu Liang, Eric Lin, Michelle M. Lin, Peter Lin, Tiffany Lin, Stacey Lu, Serena S. Luong, Jessica S. Ma, Li Ma, Justin N. Maghen, Sravya Mallam, Shivtaj Mann, Jason H. Melehani, Ryan C. Miller, Nitish Mittal, Carmel M. Moazez, Susie Moon, Rameen Moridzadeh, Kaley Ngo, Hanh H. Nguyen, Kambria Nguyen, Thien H. Nguyen, Angela W. Nieh, Isabella Niu, Seo-Kyung Oh, Jessica R. Ong, Randi K. Oyama, Joseph Park, Yaelim A. Park, Kimberly A. Passmore, Ami Patel, Amy A. Patel, Dhruv Patel, Tirth Patel, Katherine E. Peterson, An Huynh Pham, Steven V. Pham, Melissa E. Phuphanich, Neil D. Poria, Alexandra Pourzia, Victoria Ragland, Riki D. Ranat, Cameron M. Rice, David Roh, Solomon Rojhani, Lili Sadri, Agafe Saguros, Zainab Saifee, Manjot Sandhu, Brooke Scruggs, Lisa M. Scully, Vanessa Shih, Brian A. Shin, Tamir Sholklapper, Harnek Singh, Sumedha Singh, Sondra L. Snyder, Katelyn F. Sobotka, Sae Ho Song, Siddharth Sukumar, Halley C. Sullivan, Mark Sy, Hande Tan, Sara K. Taylor, Shivani K. Thaker, Tulsi Thakore, Gregory E. Tong, Jacinda N. Tran, Jonathan Tran, Tuan D. Tran, Vivi Tran, Cindy L. Trang, Hung G. Trinh, Peter Trinh, Han-Ching H. Tseng, Ted T. Uotani, Akram V. Uraizee, Kent K. T. Vu, Kevin K. T. Vu, Komal Wadhwani, Paluk K. Walia, Rebecca S. Wang, Shuo Wang, Stephanie J. Wang, Danica D. Wiredja, Andrew L. Wong, Daniel Wu, Xi Xue, Griselda Yanez, Yung-Hsuan Yang, Zhong Ye, Victor W. Yee, Cynthia Yeh, Yue Zhao, Xin Zheng, Anke Ziegenbalg, Jon Alkali, Ida Azizkhanian, Akash Bhakta, Luke Berry, Ryen Castillo, Sonja Darwish, Holly Dickinson, Ritika Dutta, Rahul Kumar Ghosh, Riley Guerin, Jonathan Hofman, Garrick Iwamoto, Sarah Kang, Andrew Kim, Brian Kim, Hanwool Kim, Kristine Kim, Suji Kim, Julie Ko, Michael Koenig, Alejandro LaRiviere, Clifton Lee, Jiwon Lee, Brandon Lung, Max Mittelman, Mark Murata, Yujin Park, Daniel Rothberg, Ben Sprung-Keyser, Kunal Thaker, Vivian Yip, Paul Picard, Francie Diep, Nikki Villarasa, Volker Hartenstein, Casey Shapiro, Marc Levis-Fitzgerald, Leslie Jaworski, David Loppato, Ira E. Clark, Utpal Banerjee

Publikováno v: G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3791-3800 (2019)

A variety of genetic techniques have been devised to determine cell lineage relationships during tissue development. Some of these systems monitor cell lineages spatially and/or temporally without regard to gene expression by the cells, whereas other

Externí odkaz: https://doaj.org/article/873517b69ed547f291031d338d321d26

Pseudomonas aeruginosa-induced nociceptor activation increases susceptibility to infection.

Autor: Tiffany Lin, Daisy Quellier, Jeffrey Lamb, Tiphaine Voisin, Pankaj Baral, Felix Bock, Alfrun Schönberg, Rossen Mirchev, Gerald Pier, Isaac Chiu, Mihaela Gadjeva

Publikováno v: PLoS Pathogens, Vol 17, Iss 5, p e1009557 (2021)

We report a rapid reduction in blink reflexes during in vivo ocular Pseudomonas aeruginosa infection, which is commonly attributed and indicative of functional neuronal damage. Sensory neurons derived in vitro from trigeminal ganglia (TG) were able t

Externí odkaz: https://doaj.org/article/1328f9c9f2b14d94b9c0a7a7058cf7fe