Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tiffani K. Quan"'
Autor:
Marta Radman-Livaja, Tiffani K Quan, Lourdes Valenzuela, Jennifer A Armstrong, Tibor van Welsem, Taesoo Kim, Laura J Lee, Stephen Buratowski, Fred van Leeuwen, Oliver J Rando, Grant A Hartzog
Publikováno v:
PLoS Genetics, Vol 8, Iss 7, p e1002811 (2012)
Chd proteins are ATP-dependent chromatin remodeling enzymes implicated in biological functions from transcriptional elongation to control of pluripotency. Previous studies of the Chd1 subclass of these proteins have implicated them in diverse roles i
Externí odkaz:
https://doaj.org/article/4618d4ff39504e22860d8deb0e6a7b99
Autor:
Andrew S. Myers, R. Scott Lokey, Grant A. Hartzog, Nathaniel B. Zuckerman, Walter M. Bray, Tiffani K. Quan, Joseph P. Konopelski
Publikováno v:
ChemMedChem. 7:761-765
Follow my lead! NSC 670224, previously shown to be toxic to Saccharomyces cerevisiae at low micromolar concentrations, potentially acts via a mechanism of action related to that of tamoxifen (NSC 180973), breast cancer drug. The structure of NSC 6702
Autor:
Joseph L. Bartoe, Jun Xia, Lindsay Hinck, Kogo Takamiya, William L. McKenna, Tiffani K. Quan, Jenna A. Moore, Richard L. Huganir, Benjamin K. Stafford
Publikováno v:
The Journal of Neuroscience. 26:3192-3205
In vertebrates, the receptor families deleted in colorectal cancer (DCC) and UNC5 mediate responses to the bifunctional guidance cue netrin-1. DCC mediates attraction, whereas a complex of DCC and UNC5 mediates repulsion. Thus, a primary determinant
Autor:
Sol Katzman, Grant A. Hartzog, Tiffani K. Quan, Ray F. Berkeley, Walter M. Bray, Jacob J. Kosarchuk, Nader Pourmand, Dustin A. Wride, R. Scott Lokey, Carlos Dobkin, Sean C. Nisam
Publikováno v:
Molecular bioSystems, vol 10, iss 12
Investigating the mechanisms of action (MOAs) of bioactive compounds and the deconvolution of their cellular targets is an important and challenging undertaking. Drug resistance in model organisms such as S. cerevisiae has long been a means for disco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404a1ce2e52e41bf8072d87c7214391a
https://escholarship.org/uc/item/9k7905xd
https://escholarship.org/uc/item/9k7905xd
Autor:
Grant A. Hartzog, Tiffani K. Quan
Publikováno v:
Molecular Cell. 31:2-4
In this issue of Molecular Cell, Fleming et al. (2008) show that histone H2B ubiquitylation and FACT function interdependently to facilitate nucleosome reassembly during transcription elongation, thereby demonstrating that histone posttranslational m
Autor:
Tiffani K. Quan, Tibor van Welsem, Marta Radman-Livaja, Grant A. Hartzog, TaeSoo Kim, Oliver J. Rando, Lourdes Valenzuela, Jennifer A. Armstrong, Laura J. Lee, Fred van Leeuwen, Stephen Buratowski
Publikováno v:
PLoS Genetics
PLoS Genetics, Public Library of Science, 2012, 8 (7), pp.e1002811. ⟨10.1371/journal.pgen.1002811⟩
PLoS Genetics, Vol 8, Iss 7, p e1002811 (2012)
PLoS Genetics, Public Library of Science, 2012, 8 (7), pp.e1002811. ⟨10.1371/journal.pgen.1002811⟩
PLoS Genetics, Vol 8, Iss 7, p e1002811 (2012)
Chd proteins are ATP–dependent chromatin remodeling enzymes implicated in biological functions from transcriptional elongation to control of pluripotency. Previous studies of the Chd1 subclass of these proteins have implicated them in diverse roles
Autor:
Grant A. Hartzog, Tiffani K. Quan
Publikováno v:
Genetics. 184(2)
Spt4–Spt5, a general transcription elongation factor for RNA polymerase II, also has roles in chromatin regulation. However, the relationships between these functions are not clear. Previously, we isolated suppressors of a Saccharomyces cerevisiae
Publikováno v:
RNA (New York, N.Y.). 15(7)
The DExD/H-box Prp5 protein (Prp5p) is an essential, RNA-dependent ATPase required for pre-spliceosome formation during nuclear pre-mRNA splicing. In order to understand how this protein functions, we used in vitro, biochemical assays to examine its
Publikováno v:
The Journal of biological chemistry. 277(23)
Pre-mRNA binding to the yeast U2 small nuclear ribonucleoprotein (snRNP) during prespliceosome formation requires ATP hydrolysis, the highly conserved UACUAAC box of the branch point region of the pre-mRNA, and several factors. Here we analyzed the b