Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tiffani Hui"'
Autor:
Jimin Yoon, Emmanuel E Nekongo, Jessica E Patrick, Tiffani Hui, Angela M Phillips, Anna I Ponomarenko, Samuel J Hendel, Rebecca M Sebastian, Yu Meng Zhang, Vincent L Butty, C Brandon Ogbunugafor, Yu-Shan Lin, Matthew D Shoulders
Publikováno v:
PLoS Biology, Vol 20, Iss 2, p e3001569 (2022)
The sequence space accessible to evolving proteins can be enhanced by cellular chaperones that assist biophysically defective clients in navigating complex folding landscapes. It is also possible, at least in theory, for proteostasis mechanisms that
Externí odkaz:
https://doaj.org/article/84a99207a4a64c3fae29a7c8fe2ebd4a
Publikováno v:
Journal of Chemical Theory and Computation.
Publikováno v:
Protein science : a publication of the Protein Society. 31(12)
Backbone-dependent rotamer libraries are commonly used to assign the side chain dihedral angles of amino acids when modeling protein structures. Most rotamer libraries are created by curating protein crystal structure data and using various methods t
Autor:
Natalie J, Norman, Si Tong, Bao, Lynne, Curts, Tiffani, Hui, Shao-Liang, Zheng, Tiffany, Shou, Ana, Zeghibe, Izzy, Burdick, Hannah, Fuehrer, Adrian, Huang
Publikováno v:
The Journal of organic chemistry. 87(15)
Inspired by crystal structures, we designed and achieved a catalyst-free Michael reaction for the preparation of an N1-alkyl pyrazole in a high yield (90%) with excellent regioselectivity (N1/N299.9:1). The scope of this protocol has been extended to