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pro vyhledávání: '"Tifelle, Reisinger"'
Autor:
Jonathan, Powell, Filipa, Mota, David, Steadman, Christelle, Soudy, Jeremy T, Miyauchi, Stuart, Crosby, Ashley, Jarvis, Tifelle, Reisinger, Natalie, Winfield, Graham, Evans, Aled, Finniear, Tamas, Yelland, Yi-Tai, Chou, A W Edith, Chan, Andrew, O'Leary, Lili, Cheng, Dan, Liu, Constantina, Fotinou, Carla, Milagre, John F, Martin, Haiyan, Jia, Paul, Frankel, Snezana, Djordjevic, Stella E, Tsirka, Ian C, Zachary, David L, Selwood
Publikováno v:
Journal of Medicinal Chemistry
We report the design, synthesis, and biological evaluation of some potent small-molecule neuropilin-1 (NRP1) antagonists. NRP1 is implicated in the immune response to tumors, particularly in Treg cell fragility, required for PD1 checkpoint blockade.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e56ed2e21a55c2767ecc12a8b43909b2
https://pubmed.ncbi.nlm.nih.gov/29648813
https://pubmed.ncbi.nlm.nih.gov/29648813
