Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tierra Ouellette"'
Autor:
Shoshanna C. Kahne, Tierra Ouellette, Priya Saha, Huilin Li, Michael Foley, Toshihiro Imaeda, Kazuyoshi Aso, Ryoma Hara, K. Heran Darwin, Carl Nathan, Masanori Kawasaki, Akinori Toita, Wenhu Zhan, Francesca Moraca, Gang Lin, Jeremie Vendome, Takafumi Yukawa, John Ginn, Xiuju Jiang, Mayako Michino, Kenjiro Sato, Peter T. Meinke, Hao Zhang, Kristin Burns-Huang, Rei Okamoto, Tzu-Tshin Wong, Hao-Chi Hsu
Publikováno v:
Journal of Medicinal Chemistry. 64:6262-6272
Treatment of tuberculosis (TB) currently takes at least 6 months. Latent Mycobacterium tuberculosis (Mtb) is phenotypically tolerant to most anti-TB drugs. A key hypothesis is that drugs that kill nonreplicating (NR) Mtb may shorten treatment when us
Autor:
Hao, Zhang, Hao-Chi, Hsu, Shoshanna C, Kahne, Ryoma, Hara, Wenhu, Zhan, Xiuju, Jiang, Kristin, Burns-Huang, Tierra, Ouellette, Toshihiro, Imaeda, Rei, Okamoto, Masanori, Kawasaki, Mayako, Michino, Tzu-Tshin, Wong, Akinori, Toita, Takafumi, Yukawa, Francesca, Moraca, Jeremie, Vendome, Priya, Saha, Kenjiro, Sato, Kazuyoshi, Aso, John, Ginn, Peter T, Meinke, Michael, Foley, Carl F, Nathan, K Heran, Darwin, Huilin, Li, Gang, Lin
Publikováno v:
J Med Chem
Treatment of tuberculosis (TB) currently takes at least 6 months. Latent Mycobacterium tuberculosis (Mtb) are phenotypically tolerant to most anti-TB drugs. A key hypothesis is that drugs that kill non-replicating (NR) Mtb may shorten treatment when
Autor:
Trevor Morgan, Kazuyoshi Aso, Huilin Li, Wenhu Zhan, Gang Lin, Tierra Ouellette, Peter T. Meinke, Carl Nathan, Manoj K. Ramjee, Adrian G. Wright, Hao-Chi Hsu, Toshihiro Imaeda, Mayako Michino, Kenjiro Sato, Kristin Burns-Huang, Ryoma Hara, Michael Foley, Rei Okamoto
Publikováno v:
Journal of Medicinal Chemistry. 62:9246-9253
Proteasomes of pathogenic microbes have become attractive targets for anti-infectives. Coevolving with its human host, Mycobacterium tuberculosis (Mtb) has developed mechanisms to resist host-impos...
Autor:
John Ginn, Wenhu Zhan, Gang Lin, Roland A. Cooper, Philip J. Rosenthal, Rong Wang, Tzu-Tshin Wong, Patrick K Tumwebaze, Joseph Visone, Laura A. Kirkman, George Sukenick, Björn F.C. Kafsack, Judith I. Okoro, Pradeep K. Singh, Hao Zhang, Ryan M. Scales, Jacob C. Harris, Peter T. Meinke, Tierra Ouellette
Publikováno v:
Journal of Medicinal Chemistry. 62:6137-6145
The Plasmodium proteasome (Pf20S) emerged as a target for antimalarials. Pf20S inhibitors are active at multiple stages of the parasite life cycle and synergize with artemisinins, suggesting that Pf20S inhibitors have potential to be prophylactic, th
Autor:
Wenhu, Zhan, Hao-Chi, Hsu, Trevor, Morgan, Tierra, Ouellette, Kristin, Burns-Huang, Ryoma, Hara, Adrian G, Wright, Toshihiro, Imaeda, Rei, Okamoto, Kenjiro, Sato, Mayako, Michino, Manoj, Ramjee, Kazuyoshi, Aso, Peter T, Meinke, Michael, Foley, Carl F, Nathan, Huilin, Li, Gang, Lin
Publikováno v:
J Med Chem
Proteasomes of pathogenic microbes have become attractive targets for anti-infectives. Co-evolving with its human host, Mycobacterium tuberculosis (Mtb) has developed mechanisms to resist host-imposed nitrosative and oxidative stresses. Genetic delet