Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Tierney Phillips"'
Autor:
Aaron Scott, Samuel Levy, Wayne Volkmuth, Yuhong Ning, Ceyda Coruh, Tierney Phillips, Kyle Hazen, Gulfem D Guler, Giuliana P Mognol, Maryam Nabiyouni
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 1 (2024)
Background Treatment with immune checkpoint inhibitors (ICIs) targeting programmed death-1 (PD-1) can yield durable antitumor responses, yet not all patients respond to ICIs. Current approaches to select patients who may benefit from anti-PD-1 treatm
Externí odkaz:
https://doaj.org/article/b147ca642587424f9492b1842c0275dc
Autor:
Gulfem D. Guler, Yuhong Ning, Chin-Jen Ku, Tierney Phillips, Erin McCarthy, Christopher K. Ellison, Anna Bergamaschi, Francois Collin, Paul Lloyd, Aaron Scott, Michael Antoine, Wendy Wang, Kim Chau, Alan Ashworth, Stephen R. Quake, Samuel Levy
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Circulating DNA detected in plasma can be used for diagnostic purposes. Here, the authors show that the 5-hydroxymethyl cytosine biomarker from plasma-derived cell free DNA can be used to detect early stage pancreatic cancer.
Externí odkaz:
https://doaj.org/article/86b0df71f9ca405aadfc2eb0c524c11b
Autor:
Vikas Bansal, Johann Gassenhuber, Tierney Phillips, Glenn Oliveira, Rebecca Harbaugh, Nikki Villarasa, Eric J. Topol, Thomas Seufferlein, Bernhard O. Boehm
Publikováno v:
BMC Medicine, Vol 15, Iss 1, Pp 1-14 (2017)
Abstract Background Diagnosis of monogenic as well as atypical forms of diabetes mellitus has important clinical implications for their specific diagnosis, prognosis, and targeted treatment. Single gene mutations that affect beta-cell function repres
Externí odkaz:
https://doaj.org/article/2500f8b2d58f4b1eb5f06349f4cbfb0a
Autor:
Yusuke Nakauchi, Armon Azizi, Daniel Thomas, M. Ryan Corces, Andreas Reinisch, Rajiv Sharma, David Cruz Hernandez, Thomas Köhnke, Daiki Karigane, Amy Fan, Daniel Martinez-Krams, Melissa Stafford, Satinder Kaur, Ritika Dutta, Paul Phan, Asiri Ediriwickrema, Erin McCarthy, Yuhong Ning, Tierney Phillips, Christopher K. Ellison, Gulfem D. Guler, Anna Bergamaschi, Chin-Jen Ku, Samuel Levy, Ravindra Majeti
Publikováno v:
Blood Cancer Discov
The conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) is a key step in DNA demethylation that is mediated by ten–eleven translocation (TET) enzymes, which require ascorbate/vitamin C. Here, we report the 5hmC landscape of norma
Autor:
Ravindra Majeti, Samuel Levy, Chin-Jen Ku, Anna Bergamaschi, Gulfem D. Guler, Christopher K. Ellison, Tierney Phillips, Yuhong Ning, Erin McCarthy, Asiri Ediriwickrema, Paul Phan, Ritika Dutta, Satinder Kaur, Melissa Stafford, Daniel Martinez-Krams, Amy Fan, Daiki Karigane, Thomas Köhnke, David Cruz Hernandez, Rajiv Sharma, Andreas Reinisch, M. Ryan Corces, Daniel Thomas, Armon Azizi, Yusuke Nakauchi
The conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) is a key step in DNA demethylation that is mediated by ten–eleven translocation (TET) enzymes, which require ascorbate/vitamin C. Here, we report the 5hmC landscape of norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5233ff56ad24b65a86f3b3b079cfe224
https://doi.org/10.1158/2643-3230.c.6550862
https://doi.org/10.1158/2643-3230.c.6550862
Autor:
Ravindra Majeti, Samuel Levy, Chin-Jen Ku, Anna Bergamaschi, Gulfem D. Guler, Christopher K. Ellison, Tierney Phillips, Yuhong Ning, Erin McCarthy, Asiri Ediriwickrema, Paul Phan, Ritika Dutta, Satinder Kaur, Melissa Stafford, Daniel Martinez-Krams, Amy Fan, Daiki Karigane, Thomas Köhnke, David Cruz Hernandez, Rajiv Sharma, Andreas Reinisch, M. Ryan Corces, Daniel Thomas, Armon Azizi, Yusuke Nakauchi
Supplementary Figure from The Cell Type–Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and TET2-Mutant Preleukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8621fa9c5111c4ded2a92efd692b23
https://doi.org/10.1158/2643-3230.22545134
https://doi.org/10.1158/2643-3230.22545134
Autor:
Ravindra Majeti, Samuel Levy, Chin-Jen Ku, Anna Bergamaschi, Gulfem D. Guler, Christopher K. Ellison, Tierney Phillips, Yuhong Ning, Erin McCarthy, Asiri Ediriwickrema, Paul Phan, Ritika Dutta, Satinder Kaur, Melissa Stafford, Daniel Martinez-Krams, Amy Fan, Daiki Karigane, Thomas Köhnke, David Cruz Hernandez, Rajiv Sharma, Andreas Reinisch, M. Ryan Corces, Daniel Thomas, Armon Azizi, Yusuke Nakauchi
Supplementary Table from The Cell Type–Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and TET2-Mutant Preleukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f36140c899911e2f8d8821485c62e4
https://doi.org/10.1158/2643-3230.22545131
https://doi.org/10.1158/2643-3230.22545131
Autor:
David Haan, Anna Bergamaschi, Verena Friedl, Gulfem D. Guler, Yuhong Ning, Roman Reggiardo, Michael Kesling, Micah Collins, Bill Gibb, Kyle Hazen, Steve Bates, Michael Antoine, Carolina Fraire, Vanessa Lopez, Roger Malta, Maryam Nabiyouni, Albert Nguyen, Tierney Phillips, Michael Riviere, Anna Leighton, Christopher Ellison, Erin McCarthy, Aaron Scott, Lauren Gigliotti, Eric Nilson, Judith Sheard, Melissa Peters, Kelly Bethel, Shimul Chowdhury, Wayne Volkmuth, Samuel Levy
Publikováno v:
Clinical Gastroenterology and Hepatology.
Autor:
Martin Sjöström, Shuang G. Zhao, Samuel Levy, Meng Zhang, Yuhong Ning, Raunak Shrestha, Arian Lundberg, Cameron Herberts, Adam Foye, Rahul Aggarwal, Junjie T. Hua, Haolong Li, Anna Bergamaschi, Corinne Maurice-Dror, Ashutosh Maheshwari, Sujun Chen, Sarah W.S. Ng, Wenbin Ye, Jessica Petricca, Michael Fraser, Lisa Chesner, Marc D. Perry, Thaidy Moreno-Rodriguez, William S. Chen, Joshi J. Alumkal, Jonathan Chou, Alicia K. Morgans, Tomasz M. Beer, George V. Thomas, Martin Gleave, Paul Lloyd, Tierney Phillips, Erin McCarthy, Michael C. Haffner, Amina Zoubeidi, Matti Annala, Robert E. Reiter, Matthew B. Rettig, Owen N. Witte, Lawrence Fong, Rohit Bose, Franklin W. Huang, Jianhua Luo, Anders Bjartell, Joshua M. Lang, Nupam P. Mahajan, Primo N. Lara, Christopher P. Evans, Phuoc T. Tran, Edwin M. Posadas, Chuan He, Xiao-Long Cui, Jiaoti Huang, Wilbert Zwart, Luke A. Gilbert, Christopher A. Maher, Paul C. Boutros, Kim N. Chi, Alan Ashworth, Eric J. Small, Housheng H. He, Alexander W. Wyatt, David A. Quigley, Felix Y. Feng
Analysis of DNA methylation is a valuable tool to understand disease progression and is increasingly being used to create diagnostic and prognostic clinical biomarkers. While conversion of cytosine to 5-methylcytosine (5mC) commonly results in transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76bad0a253d51237c4e9eaa88daea36b
https://trepo.tuni.fi/handle/10024/144065
https://trepo.tuni.fi/handle/10024/144065
Autor:
Gulfem Guler, Yuhong Ning, David Haan, Michael Kesling, Ceyda Coruh, Giuliana Mognol, Tierney Phillips, Kyle Hazen, Wayne Volkmuth, Samuel Levy
Publikováno v:
Regular and Young Investigator Award Abstracts.