Zobrazeno 1 - 10
of 225
pro vyhledávání: '"Tiernan, T."'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Nicole D. Bartolo, Niall Mortimer, Mariah A. Manter, Nicholas Sanchez, Misha Riley, Tiernan T. O’Malley, Jacob M. Hooker
Publikováno v:
ACS Chemical Neuroscience. 13:3641-3660
Activation of microglial cells accompanies the progression of many neurodegenerative disorders, including Alzheimer's disease (AD). Development of molecular imaging tools specific to microglia can help elucidate the mechanism through which microglia
Autor:
Ming Jin, Brian O’Nuallain, Wei Hong, Justin Boyd, Valentina N. Lagomarsino, Tiernan T. O’Malley, Wen Liu, Charles R. Vanderburg, Matthew P. Frosch, Tracy Young-Pearse, Dennis J. Selkoe, Dominic M. Walsh
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The optimal Aβ species to target for the potential treatment of Alzheimer’s disease has not yet been established. Here, the authors describe an in vitro assay that uses extracts from brain tissue from patients with Alzheimer’s disease, and appli
Externí odkaz:
https://doaj.org/article/1b248bb1ced34f1e829628bfcb182dd4
Autor:
Ondrejcak, Tomas, Klyubin, Igor, Neng-Wei Hu, O'Malley, Tiernan T., Corbett, Grant T., Winters, Róisín, Perkinton, Michael S., Billinton, Andy, Prenderville, Jack A., Walsh, Dominic M., Rowan, Michael J.
Publikováno v:
Journal of Neuroscience; 8/9/2023, Vol. 43 Issue 32, p5870-5879, 10p
Autor:
Ming Lei, Huixin Xu, Zhangyuan Li, Zemin Wang, Tiernan T. O'Malley, Dainan Zhang, Dominic M. Walsh, Pingyi Xu, Dennis J. Selkoe, Shaomin Li
Publikováno v:
Neurobiology of Disease, Vol 85, Iss , Pp 111-121 (2016)
Epileptic activity may be more prevalent in early stage Alzheimer's disease (AD) than previously believed. Several studies report spontaneous seizures and interictal discharges in mouse models of AD undergoing age-related Aβ accumulation. The mechan
Externí odkaz:
https://doaj.org/article/f0335e4fcad6439e8aee2320f0547106
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Catherine K. Xu, Sean R. A. Devenish, Fang Qian, Samuel I. A. Cohen, Oskar Hansson, Thierry Bussiere, Georg Meisl, Sara Linse, Tiernan T. O'Malley, Katja Bernfur, Tuomas P. J. Knowles, Michele Vendruscolo, Eimantas Sileikis, Paul H. Weinreb, Tom Scheidt, Christopher M. Dobson, Martin Lundqvist
Publikováno v:
Nature Structural & Molecular Biology. 27:1125-1133
The amyloid cascade hypothesis, according to which the self-assembly of amyloid-β peptide (Aβ) is a causative process in Alzheimer’s disease, has driven many therapeutic efforts for the past 20 years. Failures of clinical trials investigating Aβ
Autor:
Monichan Phay, Alfred T Welzel, Angela D Williams, Helen P McWilliams-Koeppen, Veronika Blinder, Tiernan T O'Malley, Alan Solomon, Dominic M Walsh, Brian O'Nuallain
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137344 (2015)
Amyloid-reactive IgGs isolated from pooled blood of normal individuals (pAbs) have demonstrated clinical utility for amyloid diseases by in vivo targeting and clearing amyloidogenic proteins and peptides. We now report the following three novel findi
Externí odkaz:
https://doaj.org/article/d9c973e149054991ba50bef3823c4302
Autor:
Lucier, G. W., Nelson, K. G., Everson, R. B., Wong, T. K., Philpot, R. M., Tiernan, T., Taylor, M., Sunahara, G. I.
Publikováno v:
Environmental Health Perspectives, 1987 Dec 01. 76, 79-87.
Externí odkaz:
https://www.jstor.org/stable/3430468
Publikováno v:
Environmental Health Perspectives, 1980 Jun 01. 36, 47-62.
Externí odkaz:
https://www.jstor.org/stable/3429332