Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Tien-Chen Liu"'
Autor:
Cheng-Yu Tsai, Ying-Chang Lu, Yen-Hui Chan, Navaneethan Radhakrishnan, Yuan-Yu Chang, Shu-Wha Lin, Tien-Chen Liu, Chuan-Jen Hsu, Pei-Lung Chen, Lee-Wei Yang, Chen-Chi Wu
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 5698-5711 (2023)
Variants in the gap junction beta-2 (GJB2) gene are the most common cause of hereditary hearing impairment. However, how GJB2 variants lead to local physicochemical and structural changes in the hexameric ion channels of connexin 26 (Cx26), resulting
Externí odkaz:
https://doaj.org/article/4cc6f64e81f44b9c8a1e0e677fb5c287
Autor:
Yen-Hui Chan, Cheng-Yu Tsai, Chang-Han Ho, Ying-Chang Lu, Pei-Hsuan Lin, Ta-Ching Chen, You-Tzung Chen, Cheng-Yen Huang, Tien-Chen Liu, Chuan-Jen Hsu, Chen-Chi Wu
Publikováno v:
Stem Cell Research, Vol 69, Iss , Pp 103068- (2023)
Pathogenic variants of the WFS1 gene can cause recessive-inherited Wolfram syndrome or dominant-inherited Wolfram-like syndrome with optic atrophy and hearing impairment. Using the Sendai virus delivery system, we generated induced pluripotent stem c
Externí odkaz:
https://doaj.org/article/49e3de1a76214919a0162b874dcd28f8
Autor:
Ta-Hsuan Lo, Pei-Hsuan Lin, Wei-Chung Hsu, Po-Nien Tsao, Tien-Chen Liu, Tzong-Hann Yang, Chuan-Jen Hsu, Li-Min Huang, Chun-Yi Lu, Chen-Chi Wu
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Congenital cytomegalovirus (cCMV) infection is the most prevalent cause of non-genetic sensorineural hearing loss (SNHL) in children. However, the prognostic determinants of SNHL remain unclear. Children with cCMV infection in a tertiary hos
Externí odkaz:
https://doaj.org/article/5c06e3610c0c4067a2722627c6a7be55
Autor:
Chin-Ju Hu, Ying-Chang Lu, Cheng-Yu Tsai, Yen-Hui Chan, Pei-Hsuan Lin, Yi-Shan Lee, I.-Shing Yu, Shu-Wha Lin, Tien-Chen Liu, Chuan-Jen Hsu, Ting-Hua Yang, Yen-Fu Cheng, Chen-Chi Wu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Recessive variants of the SLC26A4 gene are an important cause of hereditary hearing impairment. Several transgenic mice with different Slc26a4 variants have been generated. However, none have recapitulated the auditory phenotypes in humans.
Externí odkaz:
https://doaj.org/article/39c68a982910479db6b294bf68ba68ea
Autor:
Yen-Hui Chan, Chang-Han Ho, Cheng-Yu Tsai, Ying-Chang Lu, Pei-Hsuan Lin, Ta-Ching Chen, You-Tzung Chen, Cheng-Yen Huang, Tien-Chen Liu, Chuan-Jen Hsu, Chen-Chi Wu
Publikováno v:
Stem Cell Research, Vol 64, Iss , Pp 102903- (2022)
Pathogenic variants of OPA1 have been associated with autosomal dominant optic atrophy (DOA), leading to optic, auditory, and other sensorineural neuropathies and myopathies. Using the Sendai virus delivery system, we generated induced pluripotent st
Externí odkaz:
https://doaj.org/article/44d5b4e1264b482692fd96e5abebf0b1
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/793a8d43615a440785ce6faa2ba421dd
Autor:
Chee-Yee Lee, Pei-Hsuan Lin, Cheng-Yu Tsai, Yu-Ting Chiang, Hong-Ping Chiou, Ko-Yin Chiang, Pei-Lung Chen, Jacob Shu-Jui Hsu, Tien-Chen Liu, Hung-Pin Wu, Chen-Chi Wu, Chuan-Jen Hsu
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1846 (2022)
Cochlear implantation is the treatment of choice for children with profound sensorineural hearing impairment (SNHI), yet the outcomes of cochlear implants (CI) vary significantly across individuals. To investigate the CI outcomes in pediatric patient
Externí odkaz:
https://doaj.org/article/669edd66984443fa8bacb226fddbebbd
Autor:
Pei-Hsuan Lin, Hung-Pin Wu, Che-Ming Wu, Yu-Ting Chiang, Jacob Shujui Hsu, Cheng-Yu Tsai, Han Wang, Li-Hui Tseng, Pey-Yu Chen, Ting-Hua Yang, Chuan-Jen Hsu, Pei-Lung Chen, Chen-Chi Wu, Tien-Chen Liu
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1523 (2022)
With diverse etiologies and clinical features, the management of pediatric auditory neuropathy spectrum disorder (ANSD) is often challenging, and the outcomes of cochlear implants (CIs) are variable. This study aimed to investigate CI outcomes in ped
Externí odkaz:
https://doaj.org/article/845f30e030954bc1afb60ad40507d29c
Autor:
Tzong-Hann Yang, Hung-Meng Huang, Wei-Chung Hsu, Po-Nien Tsao, Tien-Chen Liu, Chuan-Jen Hsu, Li-Min Huang, Chuan-Song Wu, Shih-Ming Weng, Chun-Yi Lu, Chen-Chi Wu
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248801 (2021)
Congenital cytomegalovirus (cCMV) infection is the leading environmental cause of childhood hearing impairment. However, its significance remains largely undocumented in many regions of the world. The purpose of this study was to investigate the prev
Externí odkaz:
https://doaj.org/article/540dc289df9941688657ed7ab84467c7
Publikováno v:
Journal of the Formosan Medical Association, Vol 117, Iss 2, Pp 109-116 (2018)
The high frequency information of consonant messages is important for recognition of speech. Recently, the nonlinear frequency compression (NLFC) technique has been shown to improve the speech perception in patients with high frequency hearing loss.
Externí odkaz:
https://doaj.org/article/6f517fa235ca4be3b6cc3b86b5be4345