Design, synthesis and evaluation the bioactivities of novel 1,3-dimethyl-6-amino-1H-indazole derivatives as anticancer agents.

Autor: Hoang VH; Faculty of Pharmacy, PHENIKAA University, Hanoi 12116, Viet Nam; PHENIKAA Institute for Advanced Study (PIAS), PHENIKAA University, Yen Nghia, Hadong, Hanoi 12116, Viet Nam., Trang NTK; Department of Pharmacology and Dental Therapeutics, College of Dentistry, Chosun University, Gwangju 61452, South Korea; Department of Pharmacy, Thai Binh University of Medicine and Pharmacy, Thai Binh City 06000, Viet Nam., Minh TC; Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi 100000, Viet Nam., Long LTB; Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi 100000, Viet Nam., Lan TH; Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi 100000, Viet Nam., Hue NT; Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi 100000, Viet Nam., Tien LQ; Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi 100000, Viet Nam., Nguyen TX; Department of Neurosurgery, Viet-Duc University Hospital, Hanoi 100000, Viet Nam., Nguyen YTK; College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea., Yoo H; Department of Pharmacology and Dental Therapeutics, College of Dentistry, Chosun University, Gwangju 61452, South Korea. Electronic address: hoon_yoo@chosun.ac.kr., Tran PT; Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi 100000, Viet Nam. Electronic address: thaotp@hup.edu.vn.

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2023 Jul 15; Vol. 90, pp. 117377. Date of Electronic Publication: 2023 Jun 14.