Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Tieluo Li"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a lifesaving maneuver for the management of lethal torso hemorrhage. However, its prolonged use leads to distal organ ischemia–reperfusion injury (IRI) and systemic infla
Externí odkaz:
https://doaj.org/article/bac43d1a39104a3ba5ddf060a3b3afb1
Autor:
Jiafeng Zhang, Charles F. Evans, Robert G. Conway, Zhongjun Jon Wu, Bartley P. Griffith, Tieluo Li, Jean Jeudy
Publikováno v:
Perfusion. 36:285-292
Introduction: Extracorporeal membrane oxygenation circuit performance can be compromised by oxygenator thrombosis. Stagnant blood flow in the oxygenator can increase the risk of thrombus formation. To minimize thrombogenic potential, computational fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c80675913aac24d7bdb232b0d3f591
https://doi.org/10.1177/0267659120944105
https://doi.org/10.1177/0267659120944105
Publikováno v:
ASAIO Journal. 66:524-531
In order to explore the role of a disintegrin and metalloproteinase (ADAM) proteolysis and direct mechanical damage in non-physiologic shear stress (NPSS)-caused platelet receptor shedding, the healthy donor blood treated with/without ADAM inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ce528994aa836fa88a0866570921f82
https://doi.org/10.1097/mat.0000000000001028
https://doi.org/10.1097/mat.0000000000001028
Autor:
Shigang Wang, Bartley P. Griffith, Tieluo Li, Jiafeng Zhang, Zengsheng Chen, Katherin Arias, Zhongjun J. Wu, Wenji Sun
Publikováno v:
Artif Organs
OBJECTIVE: The roles of the large membrane surface of the oxygenator and the high mechanical shear stress (HMSS) of the pump in the ECMO circuit were examined under a pediatric support setting. METHODS: A clinical centrifugal pump and a pediatric oxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87a26a420e2d42639afc009eed58b18f
https://doi.org/10.1111/aor.13646
https://doi.org/10.1111/aor.13646
Autor:
Jiafeng Zhang, Zachary B. K. Berk, Douglas Tran, Zhongjun J. Wu, Robert G. Conway, Tieluo Li, Bartley P. Griffith
Publikováno v:
Artif Organs
Extracorporeal membrane oxygenation (ECMO) has become a mainstay of therapy for patients suffering from severe respiratory failure. Ambulatory ECMO systems aim to provide long-term out-of-hospital respiratory support. As a patient’s activity level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e13dd77b8719908616b614cb47bad69
https://doi.org/10.1111/aor.13618
https://doi.org/10.1111/aor.13618
Publikováno v:
Artif Organs
The aim of this study was to examine the impact of the nonphysiological shear stress (NPSS) on platelet hemostatic function relevant to thrombosis and bleeding in mechanically assisted circulation. Fresh human blood was circulated for four hours in i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b9d3a00c2211c627e583bb2540058c
https://doi.org/10.1111/aor.13609
https://doi.org/10.1111/aor.13609
Autor:
Zachary N. Kon, Pablo G. Sanchez, Mandheer Wadhwa, Chetan Pasrija, M. Mulligan, Tieluo Li, James S. Gammie, Si M. Pham, Bartley P. Griffith, Diana L. Pratt
Publikováno v:
Annals of Surgery. 266:1091-1096
OBJECTIVE We aimed to create a reproducible lung injury model utilizing injection of mitochondrial damage-associated molecular products. Our goal was to characterize the pathophysiologic response to damage-associated molecular pattern mediated organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deacaa22f463d6d32761366320d24113
https://doi.org/10.1097/sla.0000000000002011
https://doi.org/10.1097/sla.0000000000002011
Autor:
Zengsheng Chen, Tieluo Li, Erik N. Sorensen, Nandan K. Mondal, Zhongjun J. Wu, Michael A. Sobieski, Si M. Pham, Steven C. Koenig, Hegang H. Chen, Mark S. Slaughter, Bartley P. Griffith
Publikováno v:
Molecular and Cellular Biochemistry. 433:125-137
Non-surgical bleeding (NSB) is the most common clinical complication in heart failure (HF) patients supported by continuous-flow left ventricular assist devices (CF-LVADs). In this study, oxidative stress and alteration of signal pathways leading to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c24fb3e665e507a9bf54de1aa67a512
https://doi.org/10.1007/s11010-017-3021-1
https://doi.org/10.1007/s11010-017-3021-1
The role of PI3K/Akt signaling pathway in non-physiological shear stress-induced platelet activation
Publikováno v:
Artif Organs
The PI3K/Akt signaling pathway has been implicated in playing an important role in platelet activation during hemostasis and thrombosis involving platelet-matrix interaction and platelet aggregation. Its role in non-physiological shear stress (NPSS)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b24ef60a8e19ee55ae41f3bbd1c5ffd
https://pubmed.ncbi.nlm.nih.gov/30972780
https://pubmed.ncbi.nlm.nih.gov/30972780
Autor:
Osama T. Siddiqui, Brody Wehman, Emily Aiello, Nicholas Pietris, Rachana Mishra, Sudhish Sharma, Mark F. Pittenger, Sarah B. Murthi, Grace Bigham, Sunjay Kaushal, Tieluo Li, Bartley P. Griffith
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 310:H1816-H1826
Limited therapies exist for patients with congenital heart disease (CHD) who develop right ventricular (RV) dysfunction. Bone marrow-derived mesenchymal stem cells (MSCs) have not been evaluated in a preclinical model of pressure overload, which simu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17705dc847f6a99468beb903c2f806f
https://doi.org/10.1152/ajpheart.00955.2015
https://doi.org/10.1152/ajpheart.00955.2015