The role of microvesicles and extracellular nucleic acids in neurological manifestations of SARS-Cov-2 infection

Autor: Xu, Ran, Huo, Shufan, Kränkel, Nicolle, Früh, Anton, Fischer, Silvia, Tielking, Katharina, Vajkoczy, Peter

Objective: Neurological symptoms can present relevant co-morbidities in SARS-Cov-2 infection but potential underlying pathomechanistic patterns remain unclear. Interestingly, the presence of SARS-Cov-2 RNA and protein has been shown to in anatomicall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ad6681c87cf7c40af298bb603ded111

Präparation und Visualisierung des murinen Subarachnoidalraumes (SAR) für histologische und elektronenmikroskopische (EM) Analysen

Autor: Tielking, Katharina, Xu, Ran, Timm, Sara, Schrade, Petra, Schoknecht, Felix Thomas, Ochs, Matthias, Vajkoczy, Peter

Publikováno v: 72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie; 20210606-20210609; sine loco [digital]; DOCP168 /20210604/

Objective: Histological analyses and EM visualization of local effects after subarachnoid hemorrhage (SAH) require a preservation of the anatomical structure of the SAS. However, systematical approaches for conserving SAS in animal models of SAH are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060a1ab2e83ea3f54eb8b4175ac614b9

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Die proinflammatorische Rolle undräumliche Verteilung extrazellulärer RNA (eRNA) nach experimenteller Subarachnoidalblutung (eSAH)

Autor: Tielking, Katharina, Xu, Ran, Schneider, Ulf C., Vajkoczy, Peter

Publikováno v: 70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie; 20190512-20190515; Würzburg; DOCV218 /20190508/

Objective: The activation of neuroinflammatory signaling is thought to play a critical role in injury progression in SAH. Previous research hypothesizes that endogenous eRNA is released upon tissue injury and consecutively, activates immune cells. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631fbc007d2c2d4d853fd2a0159dd56c
http://nbn-resolving.de/urn:nbn:de:0183-19dgnc2355

RNase A Inhibits Formation of Neutrophil Extracellular Traps in Subarachnoid Hemorrhage.

Autor: Früh A; Department of Neurosurgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Tielking K; Department of Neurosurgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Schoknecht F; Department of Neurosurgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Liu S; Department of Neurosurgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Schneider UC; Department of Neurosurgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Fischer S; Department of Biochemistry, Giessen University, Giessen, Germany., Vajkoczy P; Department of Neurosurgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Xu R; Department of Neurosurgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

Publikováno v: Frontiers in physiology [Front Physiol] 2021 Sep 16; Vol. 12, pp. 724611. Date of Electronic Publication: 2021 Sep 16 (Print Publication: 2021).