Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Tielin Yang"'
Publikováno v:
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-4 (2020)
Abstract Background Nakajo-Nishimura syndrome (NNS) is an autosomal recessive heredity disorder, one of a spectrum of autoinflammatory diseases named proteasome-associated autoinflammatory syndrome (PRAAS) caused by mutations of PSMB8 gene. NNS is ch
Externí odkaz:
https://doaj.org/article/6d9f0d2b14de47dc9a69bad696acce7d
Autor:
Li Liu, Yan Wen, Yujie Ning, Ping Li, Bolun Cheng, Shiqiang Cheng, Lu Zhang, Mei Ma, Xin Qi, Chujun Liang, Tielin Yang, Xiangding Chen, Lijun Tan, Hui Shen, Qing Tian, Hong-Wen Deng, Xiancang Ma, Feng Zhang, Feng Zhu
Publikováno v:
Clinical and Translational Medicine, Vol 9, Iss 1, Pp 1-9 (2020)
Abstract Backgrounds To explore the genetic correlation between schizophrenia (SCZ) and osteoporosis (OP). Design, setting, participants, measurements We conducted a trans-ethnic two-stage genetic correlation analysis of OP and SCZ, totally invoking
Externí odkaz:
https://doaj.org/article/18ca70de8fdb4565a09e08f68a1857cb
Autor:
Xiaoming Dong, Qin Zhang, Jinglan Hao, Qianwen Xie, Binbing Xu, Peng Zhang, Haicheng Lu, Qilai Huang, Tielin Yang, Gong-Hong Wei, Rong Na, Ping Gao
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Aberrant telomerase reverse transcriptase (TERT) expression is crucial for tumor survival and cancer cells escaping apoptosis. Multiple TERT-locus variants at 5p15 have been discovered in association with cancer risk, yet the underlying mechanisms an
Externí odkaz:
https://doaj.org/article/53103bcead54426d874775057ac00f58
Autor:
Ke Cao, Weiqiang Lv, Xueqiang Wang, Shanshan Dong, Xuyun Liu, Tielin Yang, Jie Xu, Mengqi Zeng, Xuan Zou, Daina Zhao, Qingqing Ma, Mu Lin, Jiangang Long, Weijin Zang, Feng Gao, Zhihui Feng, Jiankang Liu
Publikováno v:
Advanced Science, Vol 8, Iss 11, Pp n/a-n/a (2021)
Abstract Mitochondrial epigenetics is rising as intriguing notion for its potential involvement in aging and diseases, while the details remain largely unexplored. Here it is shown that among the 13 mitochondrial DNA (mtDNA) encoded genes, NADH‐deh
Externí odkaz:
https://doaj.org/article/e2bb003a08144c089c4fcc5614820b4d
Autor:
Zhijun Dai, Tian Tian, Meng Wang, Tielin Yang, Hongtao Li, Shuai Lin, Qian Hao, Peng Xu, Yujiao Deng, Linghui Zhou, Na Li, Yan Diao
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background Estrogen exposure is a widely known risk factor for BC. And the interaction of estrogen with estrogen receptor (ER) plays an important role in breast cancer development. This case–control study aims to assess the association of
Externí odkaz:
https://doaj.org/article/d3f0856d181949728e90ecd11952e978
Autor:
Tian Tian, Meng Wang, Yuyao Zhu, Wenge Zhu, Tielin Yang, Hongtao Li, Shuai Lin, Cong Dai, Yujiao Deng, Dingli Song, Na Li, Zhen Zhai, Zhi-Jun Dai
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 13, Iss , Pp 399-406 (2018)
Motor neuron and pancreas homeobox 1 (MNX1) is a key developmental gene. Previous studies found that it was upregulated in several tumors, but its role in breast cancer (BC) remains unclear. In order to have a better understanding of this gene in BC,
Externí odkaz:
https://doaj.org/article/32aa88b8c88c4324bb780d71868f16ca
Autor:
Shujun Han, Yibo Ren, Wangxiao He, Huadong Liu, Zhe Zhi, Xinliang Zhu, Tielin Yang, Yu Rong, Bohan Ma, Timothy J. Purwin, Zhenlin Ouyang, Caixia Li, Xun Wang, Xueqiang Wang, Huizi Yang, Yan Zheng, Andrew E. Aplin, Jiankang Liu, Yongping Shao
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
In BRAF mutant melanoma, inhibition of ERK1/2 induces FOXD3 and mediates RAF inhibitor resistance. Here, the authors show that ERK1/2 mediated phosphorylation regulates sumoylation of SOX10 which activates FOXD3, and depletion of SOX10 sensitises BRA
Externí odkaz:
https://doaj.org/article/829318fdf04b499a9e045b0d41cff81a
Autor:
Zhongwei Liu, Ying Lv, Yong Zhang, Fuqiang Liu, Ling Zhu, Shuo Pan, Chuan Qiu, Yan Guo, Tielin Yang, Junkui Wang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 12 (2017)
BackgroundThe matrine‐type alkaloids are bioactive components extracted from Sophora flavescens, which is used in treatment of diabetes mellitus in traditional Chinese medicine. Advanced glycation end products mediate diabetic vascular complication
Externí odkaz:
https://doaj.org/article/fa67c4002d174b7ba939dfe681bcac68
Autor:
Tingxizi Liang, Xiaoman Duan, Keli An, Qi Shen, Xigao Chen, Chen Wang, Penghui Zhang, Xiaoshu Pan, Yifan Lyv, Feng Xu, Jie Liu, Yu-Chao Zhang, Weihong Tan, Cheng Cui, Di Gao, Jun-Jie Zhu, Xiaoxiao Hu, Tielin Yang
Publikováno v:
Nature Chemistry. 12:381-390
Stimuli-responsive biomaterials that contain logic gates hold great potential for detecting and responding to pathological markers as part of clinical therapies. However, a major barrier is the lack of a generalized system that can be used to easily
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1598ae56208893038b2c3017a4a47909
https://doi.org/10.1038/s41557-020-0426-3
https://doi.org/10.1038/s41557-020-0426-3
Autor:
Shujun Han, Yibo Ren, Wangxiao He, Huadong Liu, Zhe Zhi, Xinliang Zhu, Tielin Yang, Yu Rong, Bohan Ma, Timothy J. Purwin, Zhenlin Ouyang, Caixia Li, Xun Wang, Xueqiang Wang, Huizi Yang, Yan Zheng, Andrew E. Aplin, Jiankang Liu, Yongping Shao
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
In the original version of this Article, financial support was not fully acknowledged. The PDF and HTML versions of the Article have now been corrected to include the following: The National Basic Research Program (2015CB553602 to J.L.), the National
Externí odkaz:
https://doaj.org/article/0397b8cba23e4b61a7cf62be699e24df