Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Tiekun Yan"'
Autor:
Zhanfei Wu, Hongfen Li, Youxia Liu, Fanghao Wang, Yue Xing, Wenying Li, Junya Jia, Tiekun Yan
Publikováno v:
Kidney & Blood Pressure Research, Vol 49, Iss 1, Pp 273-285 (2024)
Introduction: There are conflicting opinions regarding the use of immunosuppressant treatment in IgA nephropathy (IgAN) patients with an estimated glomerular filtration rate (eGFR) of less than 45 mL/min/1.73 m2 and persistent proteinuria with a dail
Externí odkaz:
https://doaj.org/article/eae6a48075aa42bfbed502fcd4531562
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract To explore the optimal cut-off values of Klotho for predicting all-cause and cardiovascular mortality among chronic kidney disease (CKD) patients. Klotho was measured in 40–79-year-old individuals in the NHANES 2007–2016. A total of 2418
Externí odkaz:
https://doaj.org/article/609f9263d8c44374a29bc597dc1029d3
Publikováno v:
BMC Nephrology, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background To explore the clinicopathologic features and outcomes of IgAN patients who presented with fibrinoid necrosis (FN) lesions or not and the effect of immunosuppressive (IS) treatment in IgAN patients with FN lesions as well. Methods
Externí odkaz:
https://doaj.org/article/8701913f519f495c9af4ee411d192259
Autor:
Yue Xing, Huyan Yu, Hongfen Li, Fanghao Wang, Zhanfei Wu, Wenying Li, Youxia Liu, Junya Jia, Tiekun Yan
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e28509- (2024)
Objective: We aimed to explore the relationship between the presence and intensity of glomerular IgG deposition and the occurrence of kidney progression events in IgA nephropathy (IgAN). Methods: This retrospective study encompassed a total of 1207 p
Externí odkaz:
https://doaj.org/article/748b1c83c9dd4601b5ebc5740a098829
Autor:
Ping Zhang, Yan Jiang, Chunping Xu, Linghui Zhou, Hongguang Zheng, Deqiong Xie, Minghao Guo, Xiangyang Huang, Guoyuan Lu, Hongli Jiang, Hongyu Qiu, Bicheng Liu, Shaomei Li, Qinkai Chen, Yu'ou Xia, Bengui Sun, Xiao Yang, Shiying Zhang, Shutong Du, Mindan Sun, Menghua Chen, Aimin Zhong, Xiaoling Wang, Zhanzheng Zhao, Hua Zhou, Guisen Li, Yueqin Ren, Qun Luo, Aicheng Yang, Ping Luo, Shuifu Tang, Chengyun Xu, Qin Wang, Xiaoxia Wang, Tiekun Yan, Wei He, Shuguang Qin, Weili Zhang, Lu Lv, Cheng Wang, Hong Liu, Jing Li, Qiong Wu, Chao Pan, Chuan Li, Liangliang He, Jianghua Chen
Publikováno v:
EClinicalMedicine, Vol 65, Iss , Pp 102273- (2023)
Summary: Background: Pegmolesatide, a synthetic peptide-based erythropoietin (EPO) receptor agonist, is being evaluated as an alternative to epoetin alfa for treating anemia of chronic kidney disease (CKD) in Chinese dialysis patients. There is a cri
Externí odkaz:
https://doaj.org/article/6691532a57474e01b73b507ab1143e8f
Publikováno v:
Hereditas, Vol 159, Iss 1, Pp 1-12 (2022)
Abstract Background Diabetic nephropathy (DN) is the major cause of end-stage renal disease worldwide. The mechanism of tubulointerstitial lesions in DN is not fully elucidated. This article aims to identify novel genes and clarify the molecular mech
Externí odkaz:
https://doaj.org/article/9f65804153c149a0b8f7e144fde72437
Publikováno v:
BMC Nephrology, Vol 23, Iss 1, Pp 1-7 (2022)
Abstract Objective To date, nephrotic syndrome (NS) has not been well characterized in patients with IgA nephropathy (IgAN). Whether decline in serum albumin is an ominous sign in IgAN patients with massive proteinuria remains unknown. In this study,
Externí odkaz:
https://doaj.org/article/49e399252419418a9eafc93b8a804de7
Publikováno v:
BMC Nephrology, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background The addition of sialic acid alters IgG from a pro-inflammatory state to an anti-inflammatory state. However, there is a lack of research on the changes of IgG sialylation in IgA nephropathy (IgAN). Methods This study included a to
Externí odkaz:
https://doaj.org/article/73a1e19cf0874664bc431e8cf0663562
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Diabetic kidney disease (DKD) is a major complication of diabetes mellitus, and the leading contributor of end-stage renal disease. Hence, insights into the molecular pathogenesis of DKD are urgently needed. The purpose of this article is to reveal t
Externí odkaz:
https://doaj.org/article/e4c0431d49814dd89cdceb2c0d8836b8
Publikováno v:
Therapeutic Advances in Chronic Disease, Vol 13 (2022)
Background: It is still uncertain if a dysregulated expression of activating Fc gamma receptors (FcγRs) is associated with the development of immunoglobulin A nephropathy (IgAN). Methods: RNA sequencing was used to determine the mRNA levels of type
Externí odkaz:
https://doaj.org/article/68184fed36304df8adfd8dd57e3ddd90