Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tiejian Nie"'
Autor:
Lu Huang, Li Xia, Tiejian Nie, Bozhou Cui, Jianjun Lu, Fangfang Lu, Feiyan Fan, Dongni Ren, Yuan Lu, Guodong Gao, Qian Yang
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 1, Pp 210-219 (2024)
Abstract Traumatic brain injury (TBI) is a major cause of death and disability in adults. The pathological process of TBI involves a multifactorial cascade in which kinases have been proven contribute to interactions between relevant factors and ampl
Externí odkaz:
https://doaj.org/article/0d154954740042c79cb32e11637c29a2
Autor:
Hongwei Ma, Yongheng Yang, Tiejian Nie, Rong Yan, Yue Si, Jing Wei, Mengyun Li, He Liu, Wei Ye, Hui Zhang, Linfeng Cheng, Liang Zhang, Xin Lv, Limin Luo, Zhikai Xu, Xijing Zhang, Yingfeng Lei, Fanglin Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract Hantaan virus (HTNV) is asymptomatically carried by rodents, yet causes lethal hemorrhagic fever with renal syndrome in humans, the underlying mechanisms of which remain to be elucidated. Here, we show that differential macrophage responses
Externí odkaz:
https://doaj.org/article/4b116cdb2fe640cd94f4d478ba1201d6
Autor:
Shulei He, Lu Huang, Ci Shao, Tiejian Nie, Li Xia, Bozhou Cui, Fangfang Lu, Lin Zhu, Bolin Chen, Qian Yang
Publikováno v:
Translational Neurodegeneration, Vol 10, Iss 1, Pp 1-12 (2021)
Abstract Background Blood-based test for predicting disease progression and early diagnosis of Parkinson’s disease (PD) is an unmet need in the clinic. The profiles of microRNAs (miRNAs) are regarded as potential diagnostic biomarkers for human dis
Externí odkaz:
https://doaj.org/article/093cecd3c52e4f4a8c7ce11e09cdba92
Publikováno v:
Neurobiology of Disease, Vol 122, Iss , Pp 41-48 (2019)
Protein homeostasis or proteostasis is critical for proper cellular function and survival. It relies on the balance between protein synthesis and degradation. Lysosomes play an important role in degrading and recycling intracellular components via au
Externí odkaz:
https://doaj.org/article/624a9ab0e6db4d62bf3742d4413a41ce
Autor:
Lu Huang, Zixu Mao, Pingyi Xu, Kai Tao, Qian Yang, Lin Zhu, Tiejian Nie, Sijun Hu, Ruixin Yang
Publikováno v:
Autophagy
article-version (VoR) Version of Record
article-version (VoR) Version of Record
As a highly dynamic organelle, mitochondria undergo constant fission and fusion to change their morphology and function, coping with various stress conditions. Loss of the balance between fission and fusion leads to impaired mitochondria function, wh
Autor:
Lin Zhu, Shulei He, Lu Huang, Dongni Ren, Tiejian Nie, Kai Tao, Li Xia, Fangfang Lu, Zixu Mao, Qian Yang
Publikováno v:
Aging cell. 21(6)
Accumulation of oxidative stress is highly intertwined with aging process and contributes to aging-related diseases, such as neurodegenerative diseases. Deciphering the molecular machinery that regulates oxidative stress is fundamental to further unc
Autor:
fanglin zhang, Hongwei Ma, Yongheng Yang, Tiejian Nie, Rong Yan, Yue Si, Jing Wei, Mengyun Li, He Liu, Wei Ye, Hui Zhang, Linfeng Cheng, Liang Zhang, Xin Lv, Limin Luo, Zhikai Xu, Xijing Zhang, Yingfeng Lei
Hantaan virus (HTNV) is principally maintained and transmitted by rodents in nature, the infection of which is non-pathogenic in the field or laboratory mouse, but can cause hemorrhagic fever with renal syndrome (HFRS) in human beings, a severe syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58486aa145e1890d2a619a2991f18645
https://doi.org/10.21203/rs.3.rs-1181604/v1
https://doi.org/10.21203/rs.3.rs-1181604/v1
Autor:
Shaosong Yang, Tiejian Nie, Hua She, Kai Tao, Fangfang Lu, Yiman Hu, Lu Huang, Lin Zhu, Dayun Feng, Dan He, Jing Qi, Thomas Kukar, Long Ma, Zixu Mao, Qian Yang
TFEB (transcription factor EB) regulates multiple genes involved in the process of macroautophagy/autophagy and plays a critical role in lifespan determination. However, the detailed mechanisms that regulate TFEB activity are not fully clear. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0402d6d443dc9e2b2936d13ca7b582fb
Publikováno v:
Advances in experimental medicine and biology. 1208
Autophagy is a general term for the process of the lysosomal degradation of intracellular components, a process occurring exclusively in eukaryotic cells. Based on the way that intracellular substrates are transported to lysosomes, autophagy in mamma
Autor:
Qian Yang, Ci Shao, Lin Zhu, Bolin Chen, Shulei He, Tiejian Nie, Li Xia, Fangfang Lu, Bozhou Cui, Lu Huang
Publikováno v:
Translational Neurodegeneration
Translational Neurodegeneration, Vol 10, Iss 1, Pp 1-12 (2021)
Translational Neurodegeneration, Vol 10, Iss 1, Pp 1-12 (2021)
Background Blood-based test for predicting disease progression and early diagnosis of Parkinson’s disease (PD) is an unmet need in the clinic. The profiles of microRNAs (miRNAs) are regarded as potential diagnostic biomarkers for human diseases, wh