Výsledky vyhledávání - "Tiedtke, Arno"

Akademický článek

Secretion of functional human enzymes by Tetrahymena thermophila

Autor: Aldag Ingo, Laroy Wouter, Niebur Nadine, Bockau Ulrike, Herrmann Lutz, Weide Thomas, Contreras Roland, Tiedtke Arno, Hartmann Marcus WW

Publikováno v: BMC Biotechnology, Vol 6, Iss 1, p 19 (2006)

Abstract Background The non-pathogenic ciliate Tetrahymena thermophila is one of the best-characterized unicellular eucaryotes used in various research fields. Previous work has shown that this unicellular organism provides many biological features t

Externí odkaz: https://doaj.org/article/4f66663680c8406b8a1cc425a368e1a1

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Akademický článek

The bifunctional dihydrofolate reductase thymidylate synthase of Tetrahymena thermophila provides a tool for molecular and biotechnology applications

Autor: Tiedtke Arno, Bockau Ulrike, Herrmann Lutz, Hartmann Marcus WW, Weide Thomas

Publikováno v: BMC Biotechnology, Vol 6, Iss 1, p 21 (2006)

Abstract Background Dihydrofolate reductase (DHFR) and thymidylate synthase (TS) are crucial enzymes in DNA synthesis. In alveolata both enzymes are expressed as one bifunctional enzyme. Results Loss of this essential enzyme activities after successf

Externí odkaz: https://doaj.org/article/2b38043a8b60433d9281c4cc9fef1979

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Akademický článek

Biochemical and molecular characterisation of Tetrahymena thermophila extracellular cysteine proteases

Autor: Tiedtke Arno, Aldag Ingo, Erkelenz Michael, Herrmann Lutz, Hartmann Marcus WW

Publikováno v: BMC Microbiology, Vol 6, Iss 1, p 19 (2006)

Abstract Background Over the last decades molecular biologic techniques have been developed to alter the genome and proteome of Tetrahymena thermophila thereby providing the basis for recombinant protein expression including functional human enzymes.

Externí odkaz: https://doaj.org/article/d82f710a26724b7e86e26bdee5624d82

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