Zobrazeno 1 - 10
of 2 247
pro vyhledávání: '"Tie2"'
Autor:
Margherita Carucci, Andrew Clamp, Cong Zhou, Chris Hurt, Rosalind Glasspool, Phillip J. Monaghan, Sally Thirkettle, Michael Wheatley, Madia Mahmood, Monica Narasimham, Tracy Cox, Hilary Morrison, Susan Campbell, Annmarie Nelson, Daniella Holland-Hart, Noreen Hopewell-Kelly, Abin Thomas, Catharine Porter, Magdalena Slusarczyk, Alys Irving, Caroline Dive, Richard Adams, Gordon C. Jayson
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Anti-angiogenic, VEGF inhibitors (VEGFi) increase progression-free survival (PFS) and, in some cases, overall survival in many solid tumours. However, their use has been compromised by a lack of informative biomarkers. We have sho
Externí odkaz:
https://doaj.org/article/2cb2b6eb4c584bf9a3d37059d285edbd
Autor:
Yu Chen, Long Zhang, Xueqing Shi, Jie Han, Jingyu Chen, Xinya Zhang, Danlin Xie, Zan Li, Xing Niu, Lijie Chen, Chaoyong Yang, Xiujie Sun, Taifeng Zhou, Peiqiang Su, Na Li, Matthew B. Greenblatt, Rongqin Ke, Jianming Huang, Zhe‐Sheng Chen, Ren Xu
Publikováno v:
Advanced Science, Vol 11, Iss 18, Pp n/a-n/a (2024)
Abstract Loss of refreshment in nucleus pulposus (NP) cellularity leads to intervertebral disc (IVD) degeneration. Nevertheless, the cellular sequence of NP cell differentiation remains unclear, although an increasing body of literature has identifie
Externí odkaz:
https://doaj.org/article/9c873aa8f75840069f9fad1ac300e670
Publikováno v:
Chinese Journal of Plastic and Reconstructive Surgery, Vol 5, Iss 3, Pp 126-129 (2023)
Cutaneomucosal venous malformations (VMCMs) can manifest as sporadic or familial forms, following an autosomal dominant inheritance pattern. This report highlights the case of a 5-year-old girl presenting with a substantial congenital VMCM attributed
Externí odkaz:
https://doaj.org/article/65bb6f74e98947ae96e45a89bc439e36
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Purpose: The interaction between inflammatory cells and integrin in the endothelium plays a key role during infiltration. Previous evidence has shown that synthetic C16 peptide selectively binds to integrins αvβ3 and α5β1 and exhibits a neuroprot
Externí odkaz:
https://doaj.org/article/da88b71a7da74b42a65ec1972f450f4c
Autor:
Carlos Rafael-Vidal, Sara Martínez-Ramos, Beatriz Malvar-Fernández, Irene Altabás-González, Coral Mouriño, Douglas J. Veale, Achilleas Floudas, Ursula Fearon, José María Pego Reigosa, Samuel García
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Endothelial cell (EC) dysfunction is a hallmark of Systemic Lupus Erythematosus (SLE) and Tie2 is a receptor essential for vascular stability. Inflammatory processes promote inhibition of Tie2 homeostatic activation, driving vascular dysfunction. In
Externí odkaz:
https://doaj.org/article/8581c997c1614d2199f85464775b57a8
Autor:
Yang Pan, Takeshi Iwata
Publikováno v:
Children, Vol 11, Iss 4, p 454 (2024)
Childhood glaucoma, a significant cause of global blindness, represents a heterogeneous group of disorders categorized into primary or secondary forms. Primary childhood glaucoma stands as the most prevalent subtype, comprising primary congenital gla
Externí odkaz:
https://doaj.org/article/e97166d1ff02476fbd6f7ef4a00786f8
Akademický článek
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Autor:
Kaloss, Alexandra M.
Strokes are a leading cause of death and disability in the United States, predominantly caused by ischemic events. Ischemic strokes occur when a clot or other obstruction lodges in a blood vessel of the brain, restricting the movement of blood. Subse
Externí odkaz:
http://hdl.handle.net/10919/116094
Autor:
Cristine Dieter, Natália Emerim Lemos, Nathalia Rodrigues de Faria Corrêa, Taís Silveira Assmann, Felipe Mateus Pellenz, Luís Henrique Canani, Letícia de Almeida Brondani, Andrea Carla Bauer, Daisy Crispim
Publikováno v:
Archives of Endocrinology and Metabolism, Vol 67, Iss 5 (2023)
ABSTRACT Objective: The objective of this study was to investigate the association between SNPs in the TIE2 and ANGPT-1 genes and diabetic retinopathy (DR). Subjects and methods: This study comprised 603 patients with type 2 diabetes mellitus (T2DM)
Externí odkaz:
https://doaj.org/article/04aff3dd867d4d688028b1966c5aa803
Publikováno v:
Open Life Sciences, Vol 19, Iss 1, Pp 771619-202 (2024)
Externí odkaz:
https://doaj.org/article/8847fdc0dc534145a24deef1c5e45a54