Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Tie‐Jun Sten Shi"'
Autor:
Oscar Aubi, Karina S. Prestegård, Kunwar Jung-KC, Tie-Jun Sten Shi, Ming Ying, Ann Kari Grindheim, Tanja Scherer, Arve Ulvik, Adrian McCann, Endy Spriet, Beat Thöny, Aurora Martinez
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Phenylketonuria (PKU) is caused by autosomal recessive variants in phenylalanine hydroxylase (PAH) and can lead to neurotoxicity. Here the authors describe a mouse model of PKU based on a mutation in phenylalanine hydroxylase (R261Q) which replicates
Externí odkaz:
https://doaj.org/article/020954ecba5d415e91bb8d1edb0ad49b
Publikováno v:
Journal of Pain Research. 13:419-429
Background G protein-gated inwardly rectifying potassium (GIRK) channels are involved in the regulation of neuronal excitability. Four GIRK subunits (GIRK1-4) are expressed in rat dorsal root ganglia (DRGs). Recently, we have characterized the expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c79ddae4926271031891128ecf7ff2a8
https://doi.org/10.2147/jpr.s233744
https://doi.org/10.2147/jpr.s233744
Autor:
Karina S. Prestegård, Tanja Scherer, Ming Ying, Nenad Blau, Beat Thöny, Aurora Martinez, Ana Jorge-Finnigan, Tie-Jun Sten Shi, Nastassja Himmelreich, Kunwar Jung-KC
Publikováno v:
Human Mutation. 40:483-494
DNAJC12, a type III member of the HSP40/DNAJ family, has been identified as the specific co-chaperone of phenylalanine hydroxylase (PAH) and the other aromatic amino acid hydroxylases. DNAJ proteins work together with molecular chaperones of the HSP7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::969f2baf81ad1f24ac2c2ac7bce59d93
https://doi.org/10.1002/humu.23712
https://doi.org/10.1002/humu.23712
Autor:
Ming Ying, Ann Kari Grindheim, Kunwar Jung-KC, Tie-Jun Sten Shi, Beat Thöny, Arve Ulvik, Endy Spriet, Tanja Scherer, Aurora Martinez, Oscar Aubi, Adrian McCann, Karina S. Prestegård
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Phenylketonuria (PKU) is caused by autosomal recessive variants in phenylalanine hydroxylase (PAH), leading to systemic accumulation of L-phenylalanine (L-Phe) that may reach neurotoxic levels. A homozygous Pah-R261Q mouse, with a highly prevalent mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::504aef90adc8d00cfb5e6de509d0f5db
https://doi.org/10.1038/s41467-021-22107-1
https://doi.org/10.1038/s41467-021-22107-1
Publikováno v:
Journal of Pain Research. 10:2079-2087
Background The proapoptotic molecule BAX, plays an important role in mitochondrial apoptotic pathway. Dorsal root ganglion (DRG) neurons depend on neurotrophic factors for survival at early developmental stages. Withdrawal of neurotrophic factors wil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67a8e0eadebd1199f7e26284e11894a2
https://doi.org/10.2147/jpr.s133087
https://doi.org/10.2147/jpr.s133087
Autor:
Mathias Uhlén, Xue-Hui Cai, Jan Mulder, Chuang Lyu, Tie-Jun Sten Shi, Tomas Hökfelt, Gong-Wei Lyu
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
FRMD6, a member of the group of FERM-domain proteins, is involved both in communication between cells, interactions with extracellular matrix, cellular apoptotic and regenerative mechanisms. FRMD6 was first discovered in the rodent sciatic nerve, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dcda28250fe63c4934ececa922471da
https://hdl.handle.net/11250/2736455
https://hdl.handle.net/11250/2736455
Autor:
Kunwar Jung‐KC, Nastassja Himmelreich, Karina S. Prestegård, Tie‐Jun Sten Shi, Tanja Scherer, Ming Ying, Ana Jorge‐Finnigan, Beat Thöny, Nenad Blau, Aurora Martinez
Publikováno v:
Human Mutation. 40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29ce7445dded4631ef0f0e2341366742
https://doi.org/10.1002/humu.23727
https://doi.org/10.1002/humu.23727
Autor:
Kang Zheng, Jie Su, Gong-Wei Lyu, Tie-Jun Sten Shi, Zhi-Qing David Xu, Tomas Hökfelt, Chuang Lyu, Xin-Peng Dun, Swapnali Barde, Sheng Xia
Publikováno v:
Neuropeptides. 79:102000
The neuropeptide galanin functions via three G-protein coupled receptors, Gal1-3-R. Both Gal1-R and 2-R are involved in pain signaling at the spinal level. Here a Gal2-R-EGFP transgenic (TG) mouse was generated and studied in pain tests and by charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e49ee8048c2a924b9339f879b3d461fc
https://doi.org/10.1016/j.npep.2019.102000
https://doi.org/10.1016/j.npep.2019.102000
Autor:
Tie-Jun Sten Shi, Deyao Zhao, Min Chen, Yushen Jin, Xiuli Yue, Yunhui Zhao, Zicai Liang, Xiaoxia Wang, Huiqing Cao, Xiaorui Han, Renfa Liu, Xiaolong Liang, Yanyan Li, Shuquan Zheng, Yidi Wu
Publikováno v:
RSC Advances. 6:113745-113753
A hybrid cationic bicellar nanodisc was prepared by a conventional Bangham method in combination with a sol–gel reaction and self-assembly process. The relatively small size and disc-like shape was very stable because the incorporation of the organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c1277ef11d0f3975f1cddca5ec4ca77
https://doi.org/10.1039/c6ra24268e
https://doi.org/10.1039/c6ra24268e
Autor:
Tie-Jun Sten Shi1,2,3 Tiejun.Shi@ki.se, Qiong Xiang1,2 xq_119@163.com, Ming-Dong Zhang1,4 mingdong.zhang@ki.se, Barde, Swapnali1 swapnali.barde@ki.se, Kai-Larsenl, Ylva1,4 ylva.kai-larsen@ki.se, Fried, Kaj1 kaj.fried@ki.se, Josephson, Anna1 anna.josephson@ki.se, Glück, Laura5 laura.glueck@mti.uni-jena.de, Deyev, Sergey M.6 deyev@mail.ibch.ru, Zvyagin, Andrei V.7 andrei.zvyagin@mq.edu.au, Schulz, Stefan5 stefan.schulz@med.uni-jena.de, Hökfelt, Tomas1 tomas.hokfelt@ki.se
Publikováno v:
Molecular Pain. 2014, Vol. 10 Issue 1, p3-38. 36p. 6 Color Photographs, 1 Black and White Photograph, 3 Graphs.